Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Receptors, Nicotinic / metabolism"'
Autor:
David Wilson, Julien Giribaldi, Norelle L. Daly, Yves Haufe, Edward R. J. Evans, Sébastien Dutertre, Annette Nicke, Christine Enjalbal
Publikováno v:
Marine Drugs
Volume 19
Issue 3
Marine drugs
Marine drugs, MDPI, 2021, 19 (3), pp.141. ⟨10.3390/md19030141⟩
Marine drugs, 2021, 19 (3), pp.141. ⟨10.3390/md19030141⟩
Marine Drugs, Vol 19, Iss 141, p 141 (2021)
Volume 19
Issue 3
Marine drugs
Marine drugs, MDPI, 2021, 19 (3), pp.141. ⟨10.3390/md19030141⟩
Marine drugs, 2021, 19 (3), pp.141. ⟨10.3390/md19030141⟩
Marine Drugs, Vol 19, Iss 141, p 141 (2021)
International audience; Cone snails are venomous marine predators that rely on fast-acting venom to subdue their prey and defend against aggressors. The conotoxins produced in the venom gland are small disulfide-rich peptides with high affinity and s
Autor:
Maximilian Kleinert, Josefine Reber, Tim Gruber, Emmani B.M. Nascimento, Timo D. Müller, Stephan Sachs, Patrick Schrauwen, Martin Jastroch, Susanna M. Hofmann, Brian Finan, Vasilis Ntziachristos, Christoffer Clemmensen, Matthias H. Tschöp, Gerald Grandl, Annette Feuchtinger, Michael A. Cowley, Carmelo Quarta, Stephanie E. Simonds, Sigrid Jall, Angelos Karlas, Susanne Keipert, Daniela Loher, Eva Sanchez-Quant, Katrin Fischer
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Clemmensen, C, Jall, S, Kleinert, M, Quarta, C, Gruber, T, Reber, J, Sachs, S, Fischer, K, Feuchtinger, A, Karlas, A, Simonds, S E, Grandl, G, Loher, D, Sanchez-Quant, E, Keipert, S, Jastroch, M, Hofmann, S M, Nascimento, E B M, Schrauwen, P, Ntziachristos, V, Cowley, M A, Finan, B, Müller, T D & Tschöp, M H 2018, ' Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes ', Nature Communications, vol. 9, 4304 . https://doi.org/10.1038/s41467-018-06769-y
Nature Communications, 9:4304. Nature Publishing Group
Nat. Commun. 9:4304 (2018)
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Clemmensen, C, Jall, S, Kleinert, M, Quarta, C, Gruber, T, Reber, J, Sachs, S, Fischer, K, Feuchtinger, A, Karlas, A, Simonds, S E, Grandl, G, Loher, D, Sanchez-Quant, E, Keipert, S, Jastroch, M, Hofmann, S M, Nascimento, E B M, Schrauwen, P, Ntziachristos, V, Cowley, M A, Finan, B, Müller, T D & Tschöp, M H 2018, ' Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes ', Nature Communications, vol. 9, 4304 . https://doi.org/10.1038/s41467-018-06769-y
Nature Communications, 9:4304. Nature Publishing Group
Nat. Commun. 9:4304 (2018)
Pharmacological stimulation of brown adipose tissue (BAT) thermogenesis to increase energy expenditure is progressively being pursued as a viable anti-obesity strategy. Here, we report that pharmacological activation of the cold receptor transient re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::101ff71e3282c5fe6bf40d3b607f7b73
https://mediatum.ub.tum.de/doc/1510435/document.pdf
https://mediatum.ub.tum.de/doc/1510435/document.pdf
Autor:
Claire Leroy, Renaud Maroy, Fabienne Picard, Sepideh Sadaghiani, Delphine S. Courvoisier, Michel Bottlaender
Publikováno v:
NeuroImage, Vol. 79 (2013) pp. 42-51
The nicotinic system plays an important role in ordinary cognition, particularly in attention. The main nicotinic receptor in the human brain is the heteromeric α4β2 neuronal nicotinic acetylcholine receptor (nAChR), which is distributed throughout
Publikováno v:
Journal of Neurochemistry, Vol. 110, No 2 (2009) pp. 570-80
Hippocampus mossy fibre terminals activate CA3 pyramidal neurons via two distinct mechanisms, both quantal and glutamatergic: (i) rapid excitatory transmission in response to afferent action potentials and (ii) delayed and prolonged release following
Autor:
Christian Fuhrer, Jean-Charles Hoda, R. Ogier, Andreas Wiesner, Mario Raggenbass, Geraldine Allaman, Eric Charpantier, Dominik Feuerbach, Daniel Bertrand, Kyung-Hye Huh
Publikováno v:
Journal of Neuroscience, Vol. 25, No 43 (2005) pp. 9836-9849
Nicotine, a component of tobacco, is highly addictive but possesses beneficial properties such as cognitive improvements and memory maintenance. Involved in these processes is the neuronal nicotinic acetylcholine receptor (nAChR) α7, whose activatio
Autor:
Alessandra Quercioli, Fabrizio Montecucco, François Mach, Franco Dallegri, Giorgio Luciano Viviani
Publikováno v:
Expert Review of Cardiovascular Therapy
Expert Review of Cardiovascular Therapy, Vol. 8, No 10 (2010) pp. 1457-1467
Expert Review of Cardiovascular Therapy; Vol 8
Expert Review of Cardiovascular Therapy, Vol. 8, No 10 (2010) pp. 1457-1467
Expert Review of Cardiovascular Therapy; Vol 8
Nicotinic acid (at a daily dose of grams) has been shown to induce potent anti-atherosclerotic effects in human and animal models. Evidence from clinical studies performed in the 1950s has shown that nicotinic acid treatment remarkably improves the p
Autor:
Shaw, Julie L.V., Oliver, Elizabeth, Lee, Kai-Fai, Entrican, Gary, Jabbour, Henry N., Critchley, Hilary O.D., Horne, Andrew W.
Tubal ectopic pregnancy (EP) is the most common cause of maternal mortality in the first trimester of pregnancy; however, its etiology is uncertain. In EP, embryo retention within the Fallopian tube (FT) is thought to be due to impaired smooth muscle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::8b0e254b9247124adb79039535f410f6
http://hdl.handle.net/10722/139905
http://hdl.handle.net/10722/139905
Publikováno v:
Cell Calcium, Vol. 45, No 2 (2009) pp. 198-207
Neuronal nicotinic acetylcholine receptors (nAChRs) are Ca(2+)-permeable ligand-gated channels widely expressed in the central and peripheral nervous system. One of the most Ca(2+) selective isoform is the homopentameric alpha7-nAChR implicated in sc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b76fcb71191c5538b328253a75cdd2ea
https://archive-ouverte.unige.ch/unige:19835
https://archive-ouverte.unige.ch/unige:19835
Autor:
Daniel Bertrand, Anouk Marguerat, David J. Anderson, Eliane Tribollet, Bruce Surber, Murali Gopalakrishnan, Carol S. Surowy, Jia Du, William H. Bunnelle
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics, Vol. 324, No 1 (2008) pp. 179-187
Receptor binding was characterized for [(3)H](1S,4S)-2,2-dimethyl-5-(6-phenylpyridazin-3-yl)-5-aza-2-azoniabicycl o[2.2.1]heptane ([(3)H]A-585539), a selective high-affinity alpha7 nicotinic acetylcholine receptor (nAChR) agonist with rapid kinetics,
Autor:
Sonia Bertrand, David W. Piotrowski, Vincent E. Groppi, Theron M. Wall, Mario Raggenbass, Raymond S. Hurst, Karen L. Rutherford-Root, Nicole R. Higdon, Mihály Hajós, R. Ogier, William E. Hoffmann, Mitchell B. Berkenpas, Daniel Bertrand, Stephen P. Arneric, Geraldine Allaman, Judy A. Lawson
Publikováno v:
Journal of Neuroscience, Vol. 25, No 17 (2005) pp. 4396-4405
Several lines of evidence suggest a link between the alpha7 neuronal nicotinic acetylcholine receptor (nAChR) and brain disorders including schizophrenia, Alzheimer's disease, and traumatic brain injury. The present work describes a novel molecule, 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffa11afca755e5e116ae17757f441993
https://europepmc.org/articles/PMC6725110/
https://europepmc.org/articles/PMC6725110/