Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Receptors, Interferon/genetics"'
Autor:
Richard B. Warren, Jenny Hankinson, Patrick M. Gaffney, Magnus Rattray, Oliver Gough, Stephen Eyre, Gisela Orozco, Kate Duffus, Annie Yarwood, Chenfu Shi, Yao Fu, James Ding, Amanda McGovern, Paul Martin, Helen Ray-Jones, Vasanthipriyadarshini Gaddi
Publikováno v:
Shi, C, Ray-Jones, H, Ding, J, Duffus, K, Fu, Y, Gaddi, V P, Gough, O, Hankinson, J, Martin, P, McGovern, A, Yarwood, A, Gaffney, P, Eyre, S, Rattray, M, Warren, R B & Orozco, G 2021, ' Chromatin Looping Links Target Genes with Genetic Risk Loci for Dermatological Traits ', The Journal of Investigative Dermatology, vol. 141, no. 8, pp. 1975-1984 . https://doi.org/10.1016/j.jid.2021.01.015
Chromatin looping between regulatory elements and gene promoters presents a potential mechanism whereby disease risk variants affect their target genes. In this study, we use H3K27ac HiChIP, a method for assaying the active chromatin interactome in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d10994e884e95df7c74f8f969732cb8
https://research.manchester.ac.uk/en/publications/91e6427b-0c9e-4dfa-8686-9d2cb38a339a
https://research.manchester.ac.uk/en/publications/91e6427b-0c9e-4dfa-8686-9d2cb38a339a
Autor:
Daniel Schnepf, Nils Lycke, Valentina Bernasconi, Hans Henrik Gad, Jan Becker, Yakup Tanriver, Karolina Ebert, Rune Hartmann, Liang Ye, Peter Staeheli
Publikováno v:
Ye, L, Schnepf, D, Becker, J, Ebert, K, Tanriver, Y, Bernasconi, V, Gad, H H, Hartmann, R, Lycke, N & Staeheli, P 2019, ' Interferon-λ enhances adaptive mucosal immunity by boosting release of thymic stromal lymphopoietin ', Nature Immunology, vol. 20, no. 5, pp. 593-601 . https://doi.org/10.1038/s41590-019-0345-x
Interferon-λ (IFN-λ) acts on mucosal epithelial cells and thereby confers direct antiviral protection. In contrast, the role of IFN-λ in adaptive immunity is far less clear. Here, we report that mice deficient in IFN-λ signaling exhibited impaire
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62ff9cbee59331ae55971b8a53ef7e1a
https://pure.au.dk/portal/da/publications/interferon-enhances-adaptive-mucosal-immunity-by-boosting-release-of-thymic-stromal-lymphopoietin(103ab490-cd68-4f02-8921-47100722608f).html
https://pure.au.dk/portal/da/publications/interferon-enhances-adaptive-mucosal-immunity-by-boosting-release-of-thymic-stromal-lymphopoietin(103ab490-cd68-4f02-8921-47100722608f).html
Autor:
Pavel Taimr, André G. Uitterlinden, Cornelia M. van Duijn, Aaron Isaacs, Bruno H. Stricker, Willem P. Brouwer, Elisabeth P.C. Plompen, Harry L.A. Janssen, Jeoffrey N.L. Schouten, Frank W.G. Leebeek, Bettina E. Hansen, Sarwa Darwish Murad, Daan W. Loth, Albert Hofman
Publikováno v:
Gut, 64(4), 692-694. BMJ Publishing Group
Gut, 64(4), 692-4. BMJ Publishing Group
Gut, 64(4), 692-4. BMJ Publishing Group
Dear Editor, Increasing evidence suggests that genetic factors play a role in the multifactorial aetiology of liver fibrosis. In their recent paper, Zhao et al 1 support this by describing the role of the Jnk1 gene in liver fibrogenesis. Previously,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b557f27f143b8d04c99a367582094194
https://doi.org/10.1136/gutjnl-2014-308398
https://doi.org/10.1136/gutjnl-2014-308398
Autor:
Martina Svensson, Kate Lykke Lambertsen, Shohreh Issazadeh-Navikas, Yawei Liu, Bettina Hjelm Clausen, Reza Khorooshi, Totte Stankovich, Tomas Deierborg, Ana R. Inácio, Krzysztof Kucharz, Yiyi Yang
Publikováno v:
Journal of Neuroinflammation
Journal of Neuroinflammation, BioMed Central, 2015, 12 (1), pp.211. ⟨10.1186/s12974-015-0427-0⟩
Inacio, A R, Liu, Y, Clausen, B H, Svensson, M, Kucharz, K, Yang, Y, Stankovich, T, Khorooshi, R M H, Lambertsen, K L, Issazadeh-Navikas, S & Deierborg, T 2015, ' Endogenous IFN-β signaling exerts anti-inflammatory actions in experimentally induced focal cerebral ischemia ', Journal of Neuroinflammation, vol. 12, 211 . https://doi.org/10.1186/s12974-015-0427-0
Journal of Neuroinflammation, BioMed Central, 2015, 12 (1), pp.211. ⟨10.1186/s12974-015-0427-0⟩
Inacio, A R, Liu, Y, Clausen, B H, Svensson, M, Kucharz, K, Yang, Y, Stankovich, T, Khorooshi, R M H, Lambertsen, K L, Issazadeh-Navikas, S & Deierborg, T 2015, ' Endogenous IFN-β signaling exerts anti-inflammatory actions in experimentally induced focal cerebral ischemia ', Journal of Neuroinflammation, vol. 12, 211 . https://doi.org/10.1186/s12974-015-0427-0
Background Interferon (IFN)-β exerts anti-inflammatory effects, coupled to remarkable neurological improvements in multiple sclerosis, a neuroinflammatory condition of the central nervous system. Analogously, it has been hypothesized that IFN-β, by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::163e46687cdd8b6f4037e9aca6917ea3
https://doi.org/10.1186/s12974-015-0427-0
https://doi.org/10.1186/s12974-015-0427-0
Autor:
Arsenijevic D, Garcia I, Vesin C, Vesin D, Arsenijevic Y, Seydoux J, Girardier L, Ryffel B, Abdul DULLOO, Richard D
Publikováno v:
Europe PubMed Central
European Cytokine Network, Vol. 11, No 4 (2000) pp. 662-668
European Cytokine Network, Vol. 11, No 4 (2000) pp. 662-668
Lipopolysaccharide (LPS)-induced effects on energy balance are characterized by alterations in energy expenditure (hypermetabolism) and food intake (anorexia). To study the role of tumour necrosis factor alpha (TNF-alpha) on some of these metabolic r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::093d0c85eacd6982238c7de3a8533a44
http://europepmc.org/abstract/med/11125311
http://europepmc.org/abstract/med/11125311