Toward Understanding How Staphylococcal Protein A Inhibits IgG-Mediated Phagocytosis

Autor: Cruz, Ana Rita, Bentlage, Arthur E H, Blonk, Robin, de Haas, Carla J C, Aerts, Piet C, Scheepmaker, Lisette M, Bouwmeester, Inge G, Lux, Anja, van Strijp, Jos A G, Nimmerjahn, Falk, van Kessel, Kok P M, Vidarsson, Gestur, Rooijakkers, Suzan H M, Afd Biomol.Mass Spect. and Proteomics, Biomolecular Mass Spectrometry and Proteomics

Publikováno v: Journal of Immunology, 209(6), 1146. American Association of Immunologists
Journal of Immunology, 209(6), 1146-1155. American Association of Immunologists

IgG molecules are crucial for the human immune response against bacterial infections. IgGs can trigger phagocytosis by innate immune cells, like neutrophils. To do so, IgGs should bind to the bacterial surface via their variable Fab regions and inter

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4787bbc5ea6d493a41b557e83d6ee51f
https://dspace.library.uu.nl/handle/1874/426909

Monocyte subpopulation profiling indicates CDK6-derived cell differentiation and identifies subpopulation-specific miRNA expression sets in acute and stable coronary artery disease

Autor: Witten, Anika, Martens, Leonie, Schäfer, Ann-Christin, Troidl, Christian, Pankuweit, Sabine, Vlacil, Ann-Kathrin, Oberoi, Raghav, Schieffer, Bernhard, Grote, Karsten, Stoll, Monika, Markus, Birgit

Publikováno v: Scientific Reports, 12(1):5589. Nature Publishing Group

Coronary artery disease (CAD) is a long-lasting inflammatory disease characterized by monocyte migration into the vessel wall leading to clinical events like myocardial infarction (MI). However, the role of monocyte subsets, especially their miRNA-dr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::7eb7eff442d3ec6fa22a63645b60f465
https://cris.maastrichtuniversity.nl/en/publications/3982a2b9-3697-4629-9d1a-9562fac5d8d4

Outcomes of controlled human malaria infection after BCG vaccination

Autor: Christine Stabell Benn, Farid Keramati, Robert W. Sauerwein, Marga van de Vegte-Bolmer, Quirijn de Mast, Rianne Stoter, Marije C. Behet, Geert-Jan van Gemert, Rob J.W. Arts, Wouter Graumans, Peter Aaby, Reinout van Crevel, Karina Teelen, Simone J.C.F.M. Moorlag, Annie S. P. Yang, Jona Walk, Cornelus C. Hermsen, L. Charlotte J. de Bree, André J. A. M. van der Ven, Mihai G. Netea

Publikováno v: Nature Communications, 10
Nature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
Walk, J, de Bree, L C J, Graumans, W, Stoter, R, van Gemert, G J, van de Vegte-Bolmer, M, Teelen, K, Hermsen, C C, Arts, R J W, Behet, M C, Keramati, F, Moorlag, S J C F M, Yang, A S P, van Crevel, R, Aaby, P, de Mast, Q, van der Ven, A J A M, Stabell Benn, C, Netea, M G & Sauerwein, R W 2019, ' Outcomes of controlled human malaria infection after BCG vaccination ', Nature Communications, vol. 10, 874 . https://doi.org/10.1038/s41467-019-08659-3
Nature Communications

Recent evidence suggests that certain vaccines, including Bacillus-Calmette Guérin (BCG), can induce changes in the innate immune system with non-specific memory characteristics, termed ‘trained immunity’. Here we present the results of a random

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df028d745c66717cd0089fe85eabd210
https://hdl.handle.net/2066/202100

Neutrophils Kill Antibody-Opsonized Cancer Cells by Trogoptosis

Autor: Jutte van der Werff ten Bosch, Taco W. Kuijpers, Takashi Matozaki, Michel van Houdt, Dieke J van Rees, Paul Kubes, René A. W. van Lier, Catharina W Menke-van der Houven van Oordt, Jeanette H. W. Leusen, Paul Verkuijlen, Katka Franke, Xi Wen Zhao, Liane Babes, Jaap Jan Boelens, Karin Schornagel, Eiji Suzuki, Sergio Rutella, Karl Seeger, Hanke L. Matlung, Hans Janssen, Cor Lieftink, Roderick L. Beijersbergen, Dirk Roos, Louise W. Treffers, Ingrid Kühnle, Timo K. van den Berg, Daria Pagliara, Robin van Bruggen, Pasi Halonen

Publikováno v: Cell Reports, 23(13), 3946. Cell Press
Cell Reports, Vol 23, Iss 13, Pp 3946-3959.e6 (2018)
Cell reports, 23(13), 3946-3959.e6. Cell Press
Cell Reports, 23(13), 3946-3959.e6. Cell Press
Matlung, H L, Babes, L, Zhao, X W, van Houdt, M, Treffers, L W, van Rees, D J, Franke, K, Schornagel, K, Verkuijlen, P, Janssen, H, Halonen, P, Lieftink, C, Beijersbergen, R L, Leusen, J H W, Boelens, J J, Kuhnle, I, van der Werff Ten Bosch, J, Seeger, K, Rutella, S, Pagliara, D, Matozaki, T, Suzuki, E, Menke-van der Houven van Oordt, C W, van Bruggen, R, Roos, D, van Lier, R A W, Kuijpers, T W, Kubes, P & van den Berg, T K 2018, ' Neutrophils Kill Antibody-Opsonized Cancer Cells by Trogoptosis ', Cell Reports, vol. 23, no. 13, pp. 3946-3959.e6 . https://doi.org/10.1016/j.celrep.2018.05.082

Summary: Destruction of cancer cells by therapeutic antibodies occurs, at least in part, through antibody-dependent cellular cytotoxicity (ADCC), and this can be mediated by various Fc-receptor-expressing immune cells, including neutrophils. However,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ea52655291535ae8ca11d53102ba828
https://doi.org/10.1016/j.celrep.2018.05.082

Critical role of galectin-3 in phagocytosis by macrophages

Autor: Hideki Sano, Daniel K. Hsu, John R. Apgar, Lan Yu, Bhavya B. Sharma, Ichiro Kuwabara, Shozo Izui, Fu-Tong Liu

Publikováno v: Journal of Clinical Investigation, Vol. 112, No 3 (2003) pp. 389-397

Galectin-3 is a member of a large family of animal lectins. This protein is expressed abundantly by macrophages, but its function in this cell type is not well understood. We have studied the effect of galectin-3 gene targeting on phagocytosis, a maj

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c90f2896db003aeea120122481b4b1b
https://europepmc.org/articles/PMC166291/