Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Receptors, IgG/genetics"'
Autor:
Bianca Balbino, Julien Stackowicz, Kari C. Nadeau, Pauline Herviou, Ophélie Godon, Sébastien Brûlé, Delphine Sterlin, Andrew J. Murphy, Vera Voronina, Bruno Iannascoli, Odile Richard-Le Goff, Gaël A. Millot, Macdonald Lynn, Laurent L. Reber, Harris Faith, Pierre Bruhns
Publikováno v:
Journal of Clinical Investigation
Journal of Clinical Investigation, 2019, ⟨10.1172/JCI129697⟩
Journal of Clinical Investigation, American Society for Clinical Investigation, 2019, ⟨10.1172/JCI129697⟩
J Clin Invest
Journal of Clinical Investigation, 2019, ⟨10.1172/JCI129697⟩
Journal of Clinical Investigation, American Society for Clinical Investigation, 2019, ⟨10.1172/JCI129697⟩
J Clin Invest
International audience; Omalizumab is an anti-IgE monoclonal antibody (mAb) approved for the treatment of severe asthma and chronic spontaneous urticaria. Use of Omalizumab is associated with reported side effects, ranging from local skin inflammatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4c06554f4a34ad7e3a43c7c44772130
https://doi.org/10.1172/jci129697
https://doi.org/10.1172/jci129697
Autor:
Jens M. Kelm, S. Messner, T. M. de Kok, Jian Jiang, M.H.M. van Herwijnen, Danyel Jennen, J.C.S. Kleinjans
Publikováno v:
Toxicology Letters, 312, 34-44. Elsevier Ireland Ltd
Inflammation is one of the factors that may increase the sensitivity of hepatic cells to acetaminophen (APAP) induced toxicity. To investigate the mechanisms, we exposed 3-dimensional (3D) Human Liver Microtissues, a co-culture of primary human hepat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36b284f6f67c1475aa6ddc29b7c7a153
https://doi.org/10.1016/j.toxlet.2019.05.004
https://doi.org/10.1016/j.toxlet.2019.05.004
Autor:
Gelmetti, Adriana Peixoto
O Lúpus Eritematoso Sistêmico (LES) é uma doença auto-imune caracterizada pela deposição de imunocomplexos nos tecidos. O clareamento de imunocomplexos está comprometido no LES, contribuindo para a patogênese da nefrite lúpica. Os receptores
Autor:
Bengt Fadeel, Inger Vedin, Jan Palmblad, Hans Hägglund, Daniel Tesfa, Sofia Ajeganova, Anna Linda Zignego
Publikováno v:
Arthritis Research & Therapy
Background: The causes and mechanisms of late-onset neutropenia (LON) following rituximab treatment in patients with rheumatic diseases are not known. In this study, we aimed to investigate the role of established Fc gamma receptor gene (FCGR) polymo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6762eb575a8774308e62232e1ec5479
https://doi.org/10.1186/s13075-017-1241-0
https://doi.org/10.1186/s13075-017-1241-0
Autor:
Santiago J, Carmona, Sarah A, Teichmann, Lauren, Ferreira, Iain C, Macaulay, Michael J T, Stubbington, Ana, Cvejic, David, Gfeller
Publikováno v:
Genome research, vol. 27, no. 3, pp. 451-461
Genome Research
Genome Research
The immune system of vertebrate species consists of many different cell types that have distinct functional roles and are subject to different evolutionary pressures. Here, we first analyzed conservation of genes specific for all major immune cell ty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f7618ea54ba136bb4a2d5f76bebf0ba8
https://serval.unil.ch/resource/serval:BIB_9293ADF6E6AC.P001/REF.pdf
https://serval.unil.ch/resource/serval:BIB_9293ADF6E6AC.P001/REF.pdf
Autor:
Philipp Starkl, Riccardo Sibilano, Laurent L. Reber, Hajime Karasuyama, Bianca Balbino, Stephen J. Galli, Pierre Bruhns, Thomas Marichal, Mindy Tsai, Nicolas Gaudenzio
Publikováno v:
Journal of Allergy and Clinical Immunology
Journal of Allergy and Clinical Immunology, Elsevier, 2017, 139 (2), pp.584-596.e10. ⟨10.1016/j.jaci.2016.05.047⟩
Journal of Allergy and Clinical Immunology, 2017, 139 (2), pp.584-596.e10. ⟨10.1016/j.jaci.2016.05.047⟩
Journal of Allergy and Clinical Immunology, Elsevier, 2017, 139 (2), pp.584-596.e10. ⟨10.1016/j.jaci.2016.05.047⟩
Journal of Allergy and Clinical Immunology, 2017, 139 (2), pp.584-596.e10. ⟨10.1016/j.jaci.2016.05.047⟩
Background Conflicting results have been obtained regarding the roles of Fc receptors and effector cells in models of active systemic anaphylaxis (ASA). In part, this might reflect the choice of adjuvant used during sensitization because various adju
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9aa3bc6fe0560e9470ac64a04dde18b
https://hal-pasteur.archives-ouvertes.fr/pasteur-02510918
https://hal-pasteur.archives-ouvertes.fr/pasteur-02510918
Autor:
Paul W. H. I. Parren, Inger S. Nijhof, Tuna Mutis, Yannis Morel, Henk M. Lokhorst, Pascale Andre, Berris van Kessel, Niels W.C.J. van de Donk, Jeroen J. Lammerts van Bueren
Publikováno v:
Haematologica, 100(2), 263-268. Ferrata Storti Foundation
Nijhof, I S, Lammerts van Bueren, J J, van Kessel, B, Andre, P, Morel, Y, Lokhorst, H M, van de Donk, N W, Parren, P W & Mutis, T 2015, ' Daratumumab-mediated lysis of primary multiple myeloma cells is enhanced in combination with the human anti-KIR antibody IPH2102 and lenalidomide ', Haematologica, vol. 100, no. 2, pp. 263-268 . https://doi.org/10.3324/haematol.2014.117531
Nijhof, I S, van Bueren, J J L, van Kessel, B, Andre, P, Morel, Y, Lokhorst, H M, van de Donk, N W C J, Parren, P W H I & Mutis, T 2015, ' Daratumumab-mediated lysis of primary multiple myeloma cells is enhanced in combination with the human anti-KIR antibody IPH2102 and lenalidomide ', Haematologica, vol. 100, no. 2, pp. 263-268 . https://doi.org/10.3324/haematol.2014.117531
Nijhof, I S, Lammerts van Bueren, J J, van Kessel, B, Andre, P, Morel, Y, Lokhorst, H M, van de Donk, N W, Parren, P W & Mutis, T 2015, ' Daratumumab-mediated lysis of primary multiple myeloma cells is enhanced in combination with the human anti-KIR antibody IPH2102 and lenalidomide ', Haematologica, vol. 100, no. 2, pp. 263-268 . https://doi.org/10.3324/haematol.2014.117531
Nijhof, I S, van Bueren, J J L, van Kessel, B, Andre, P, Morel, Y, Lokhorst, H M, van de Donk, N W C J, Parren, P W H I & Mutis, T 2015, ' Daratumumab-mediated lysis of primary multiple myeloma cells is enhanced in combination with the human anti-KIR antibody IPH2102 and lenalidomide ', Haematologica, vol. 100, no. 2, pp. 263-268 . https://doi.org/10.3324/haematol.2014.117531
Despite recent treatment improvements, multiple myeloma remains an incurable disease. Since antibody-dependent cell-mediated cytotoxicity is an important effector mechanism of daratumumab, we explored the possibility of improving daratumumab-mediated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caef03c61a2f59fe0389a1b8d611779c
https://research.vumc.nl/en/publications/c13eee17-fa2a-4fa7-8efe-a25eee378540
https://research.vumc.nl/en/publications/c13eee17-fa2a-4fa7-8efe-a25eee378540
Autor:
David Clayton, Iva Gunnarsson, Kenneth G. C. Smith, Nguyen Hoan Phu, Sarah J. Dunstan, Paul A. Lyons, Yu-Lung Lau, Heather A. Niederer, Norbert Peshu, Tim F. Rayner, Wanling Yang, Lisa C. Willcocks, Britta C. Urban, J. Anthony G. Scott, Caroline O. S. Savage, Elisabet Svenungsson, Tran Tinh Hien, Leonid Padyukov, Thomas N. Williams, Richard A. Watts
Publikováno v:
Human Molecular Genetics
The response of a leukocyte to immune complexes (ICs) is modulated by receptors for the Fc region of IgG (FcγRs), and alterations in their affinity or function have been associated with risk of autoimmune diseases, including systemic lupus erythemat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c4f5e2b130c85931a72f3d631aed1a7
http://ora.ox.ac.uk/objects/uuid:3800ecdc-9117-4b06-91b2-0b44a54dc116
http://ora.ox.ac.uk/objects/uuid:3800ecdc-9117-4b06-91b2-0b44a54dc116
Autor:
Adriana Peixoto Gelmetti
Publikováno v:
Biblioteca Digital de Teses e Dissertações da USPUniversidade de São PauloUSP.
O Lúpus Eritematoso Sistêmico (LES) é uma doença auto-imune caracterizada pela deposição de imunocomplexos nos tecidos. O clareamento de imunocomplexos está comprometido no LES, contribuindo para a patogênese da nefrite lúpica. Os receptores
Our knowledge about the role of human Fc receptors for IgG (FcgammaR) has increased considerably within the last several years. These receptors vary in their affinity for IgG, their preferences for IgG subclasses, the cell type-specific expression pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_____10561::c2c321581c3a4e1a2c76c3967a70ff4f
http://olympias.lib.uoi.gr/jspui/handle/123456789/23120
http://olympias.lib.uoi.gr/jspui/handle/123456789/23120