Výsledky vyhledávání - "Receptors, Fibroblast Growth Factor/metabolism"

Autocrine FGF1 signaling promotes glucose uptake in adipocytes

Autor: Vera J. M. Nies, Dicky Struik, Sihao Liu, Weilin Liu, Janine K. Kruit, Michael Downes, Tim van Zutphen, Henkjan J. Verkade, Ronald M. Evans, Johan W. Jonker

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 119(40):e2122382119. NATL ACAD SCIENCES

Fibroblast growth factor 1 (FGF1) is an autocrine growth factor released from adipose tissue during over-nutrition or fasting to feeding transition. While local actions underlie the majority of FGF1’s anti-diabetic functions, the molecular mechanis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e743138547b0be6aab799b2becc0b11c
https://doi.org/10.1073/pnas.2122382119

Zobrazit plný text záznamu

Role of Klotho in Hyperglycemia: Its Levels and Effects on Fibroblast Growth Factor Receptors, Glycolysis, and Glomerular Filtration

Autor: Dorota Rogacka, Tomasz Kulesza, Patrycja Rachubik, Irena Audzeyenka, Agnieszka Piwkowska, Stefan Angielski, Marlena Typiak, Moin A. Saleem

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 7867, p 7867 (2021)
Typiak, M, Kulesza, T, Rachubik, P, Rogacka, D, Audzeyenka, I, Angielski, S, Saleem, M A & Piwkowska, A 2021, ' Role of Klotho in Hyperglycemia : Its Levels and Effects on Fibroblast Growth Factor Receptors, Glycolysis, and Glomerular Filtration ', International Journal of Molecular Sciences, vol. 22, no. 15, 7867 . https://doi.org/10.3390/ijms22157867
Volume 22
Issue 15

Hyperglycemic conditions (HG), at early stages of diabetic nephropathy (DN), cause a decrease in podocyte numbers and an aberration of their function as key cells for glomerular plasma filtration. Klotho protein was shown to overcome some negative ef

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecdb78a19e8f03e20f1e8f18c6e6e335
http://europepmc.org/articles/PMC8345972

Zobrazit plný text záznamu

Plný text ve formátu HTML

Fibroblast Growth Factor (FGF) 23 Regulates the Plasma Levels of Parathyroid Hormone In Vivo Through the FGF Receptor in Normocalcemia, But Not in Hypocalcemia

Autor: Klaus Olgaard, Maria L. Mace, Eva Gravesen, Ewa Lewin, Anders Nordholm

Publikováno v: Mace, M L, Gravesen, E, Nordholm, A, Ølgaard, K & Lewin, E 2018, ' Fibroblast Growth Factor (FGF) 23 Regulates the Plasma Levels of Parathyroid Hormone In Vivo Through the FGF Receptor in Normocalcemia, But Not in Hypocalcemia ', Calcified Tissue International, vol. 102, no. 1, pp. 85-92 . https://doi.org/10.1007/s00223-017-0333-9
Calcified Tissue International

The calcium and phosphate homeostasis is regulated by a complex interplay between parathyroid hormone (PTH), fibroblast growth factor 23 (FGF23), and calcitriol. Experimental studies have demonstrated an inhibitory effect of FG23 on PTH production an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75d5728e72a5521551aeb214e71abd36
https://doi.org/10.1007/s00223-017-0333-9

Zobrazit plný text záznamu

Structures of β-Klotho reveal a ‘zip code’-like mechanism for endocrine FGF signaling

Autor: Sangwon Lee, Jungyuen Choi, Jyotidarsini Mohanty, Leiliane P. Sousa, Francisco Tome, Els Pardon, Jan Steyaert, Mark A. Lemmon, Irit Lax, Joseph Schlessinger

Canonical fibroblast growth factors (FGFs) activate FGF receptors (FGFRs) through paracrine or autocrine mechanisms in a process that requires cooperation with heparan sulfate proteoglycans, which function as co-receptors for FGFR activation. By cont

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d1ffc8578a59fc589e666f513015207
https://europepmc.org/articles/PMC6594174/

Zobrazit plný text záznamu

Fibroblast surface-associated FGF-2 promotes contact-dependent colorectal cancer cell migration and invasion through FGFR-SRC signaling and integrin αvβ5-mediated adhesion

Autor: Pascale Anderle, Patricia Werfelli, Sarah Knuchel, Curzio Rüegg, Eva Diamantis

Publikováno v: Oncotarget, vol. 6, no. 16, pp. 14300-14317
Oncotarget

Carcinoma-associated fibroblasts were reported to promote colorectal cancer (CRC) invasion by secreting motility factors and extracellular matrix processing enzymes. Less is known whether fibroblasts may induce CRC cancer cell motility by contact- de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4928391e9aca15e991489acebd86ef05
https://serval.unil.ch/resource/serval:BIB_AD236634E8C0.P001/REF.pdf

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání