The constitutive activity of the virally encoded chemokine receptor US28 accelerates glioblastoma growth

Autor: Tian Shu Fan, Timo W.M. De Groof, Diane Van Hoorick, Henry F. Vischer, Maarten P. Bebelman, Laura Smits-de Vries, Afsar Rahbar, Marco Siderius, Jeffrey R. van Senten, Tonny Lagerweij, Raimond Heukers, Jody van Offenbeek, Raymond H. de Wit, Thomas Wurdinger, Rob Leurs, Cecilia Söderberg-Nauclér, Joao Vieira, Martine J. Smit, Sabrina M. de Munnik

Publikováno v: Oncogene
Oncogene, 37(30), 4110-4121. Nature Publishing Group
Heukers, R, Fan, T S, de Wit, R H, van Senten, J R, de Groof, T W M, Bebelman, M P, Lagerweij, T, Vieira, J, de Munnik, S M, Smits-de Vries, L, van Offenbeek, J, Rahbar, A, van Hoorick, D, Söderberg-Naucler, C, Würdinger, T, Leurs, R, Siderius, M, Vischer, H F & Smit, M J 2018, ' The constitutive activity of the virally encoded chemokine receptor US28 accelerates glioblastoma growth ', Oncogene, vol. 37, no. 30, pp. 4110-4121 . https://doi.org/10.1038/s41388-018-0255-7
Oncogene, 2018(30), 1-12. Nature Publishing Group
Heukers, R, Fan, T S, de Wit, R H, van Senten, J R, de Groof, T W M, Bebelman, M P, Lagerweij, T, Vieira, J, de Munnik, S M, Smits-de Vries, L, van Offenbeek, J, Rahbar, A, van Hoorick, D, Söderberg-Naucler, C, Würdinger, T, Leurs, R, Siderius, M, Vischer, H F & Smit, M J 2018, ' The constitutive activity of the virally encoded chemokine receptor US28 accelerates glioblastoma growth ', Oncogene, vol. 2018, no. 30, pp. 1-12 . https://doi.org/10.1038/s41388-018-0255-7

Glioblastoma (GBM) is the most aggressive and an incurable type of brain cancer. Human cytomegalovirus (HCMV) DNA and encoded proteins, including the chemokine receptor US28, have been detected in GBM tumors. US28 displays constitutive activity and i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0d2b143f496bc5734d97f476890189d
http://europepmc.org/articles/PMC6062493

An effector-reduced anti-ß-amyloid (Aß) antibody with unique aß binding properties promotes neuroprotection and glial engulfment of Aß

Autor: Yvan Varisco, Kasia Piorkowska, Maria Pihlgren, Oskar Adolfsson, Mark Z. Chen, Alvin Gogineni, Nicolas Toni, Carole Ho, Andreas Muhs, Andrea Pfeifer, Katia Antoniello, Michel Friesenhahn, Robby M. Weimer, Sophie Lohmann, Robert Paul, Valerie Gafner, Anna Lucia Buccarello, Janice A. Maloney, Deborah L. Mortensen, Ryan J. Watts, Jasvinder Atwal

Publikováno v: The Journal of neuroscience : the official journal of the Society for Neuroscience
Journal of Neuroscience, vol. 32, no. 28, pp. 9677-9689

Passive immunization against β-amyloid (Aβ) has become an increasingly desirable strategy as a therapeutic treatment for Alzheimer's disease (AD). However, traditional passive immunization approaches carry the risk of Fcγ receptor-mediated overact

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2cbe1eb7083c2049180d072e90c4036

Effects of weight loss and exercise on chemerin serum concentrations and adipose tissue expression in human obesity

Autor: Chakaroun, Rima

Chemerin is a chemoattractant adipokine that regulates adipogenesis and may induce insulin resistance. Chemerin serum concentrations are elevated in obese, insulin-resistant, and inflammatory states in vivo. Here we investigate the role of omental (O

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4178::25ddec0853133514d9bc733c2c296590
https://ul.qucosa.de/id/qucosa:13074

Chemerin expression marks early psoriatic skin lesions and correlates with plasmacytoid dendritic cell recruitment

Autor: Roberta Daniele, Ornella De Pità, Claudia Scarponi, Paola Fortugno, Safiyè Gonzalvo-Feo, Stefania Madonna, Marc Parmentier, Sabatino Pallotta, Jean-Denis Franssen, Silvano Sozzani, Giampiero Girolomoni, Cristina Albanesi, Daniela Bosisio

Publikováno v: The Journal of experimental medicine, 206 (1
Journal of Experimental Medicine; Vol 206
The Journal of Experimental Medicine

Psoriasis is a type I interferon-driven T cell-mediated disease characterized by the recruitment of plasmacytoid dendritic cells (pDC) into the skin. The molecules involved in pDC accumulation in psoriasis lesions are unknown. Chemerin is the only in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::385b592e1216bca1362e6ad027821b85
http://hdl.handle.net/11379/28462

Effects of CCR5-delta32 and CCR2-64I alleles on disease progression of perinatally HIV-1-infected children: an international meta-analysis

Autor: Ioannidis, J. P., Contopoulos-Ioannidis, D. G., Rosenberg, P. S., Goedert, J. J., De Rossi, A., Espanol, T., Frenkel, L., Mayaux, M. J., Newell, M. L., Pahwa, S. G., Rousseau, C., Scarlatti, G., Sei, S., Sen, L., O'Brien, T. R.

OBJECTIVE: Among perinatally infected children, the effects of certain alleles of the CCR5 and CCR2 genes on the rate of disease progression remain unclear. We addressed the effects of CCR5-delta32 and CCR2-64I in an international meta-analysis. METH

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_____10561::37596c8694cc20351182e274ee7f1570
http://olympias.lib.uoi.gr/jspui/handle/123456789/22116