Zobrazeno 1 - 10
of 1 771
pro vyhledávání: '"Receptor repertoire"'
Publikováno v:
ImmunoTargets and Therapy, Vol Volume 13, Pp 661-671 (2024)
Xian He,1,2 Xueping Wen,3 Peng Ming He,3 Dan Liang,2 Lihong Yang,2 Yuping Ran,1 Zhixin Zhang3 1Department of Dermatovenereology, West China Hospital, Sichuan University, Chengdu, People’s Republic of China; 2Department of Allergy, Chengdu First Peo
Externí odkaz:
https://doaj.org/article/8dcfaec0c8fc43ba8b62db0686bb8163
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Background Esophageal squamous cell carcinoma (ESCC) is a malignant neoplasm with detrimental implications for human health. The landscape of ESCC therapy has been revolutionized by the introduction of immunotherapy, specifically involving i
Externí odkaz:
https://doaj.org/article/cbff68607cde4c7eb4022dd69fc6cb51
Autor:
Yohei Funakoshi, Kimikazu Yakushijin, Goh Ohji, Takaji Matsutani, Kazuhiko Doi, Hironori Sakai, Tomoki Sasaki, Takahiro Kusakabe, Sakuya Matsumoto, Yasuyuki Saito, Shinichiro Kawamoto, Katsuya Yamamoto, Taiji Koyama, Yoshiaki Nagatani, Keiji Kurata, Shiro Kimbara, Yoshinori Imamura, Naomi Kiyota, Mitsuhiro Ito, Hironobu Minami
Publikováno v:
eJHaem, Vol 5, Iss 4, Pp 661-668 (2024)
Abstract Monovalent Omicron XBB.1.5 mRNA vaccines were newly developed and approved by the FDA in Autumn 2023 for preventing COVID‐19. However, clinical efficacy for these vaccines is currently lacking. We previously established the quantification
Externí odkaz:
https://doaj.org/article/4e80912d8731416b882b2610fa7fdb8e
Autor:
Muwen Nie, Zhao Sun, Ningning Li, Liangrui Zhou, Shuchun Wang, Mingming Yuan, Rongrong Chen, Lin Zhao, Ji Li, Chunmei Bai
Publikováno v:
Thoracic Cancer, Vol 15, Iss 19, Pp 1502-1512 (2024)
Abstract Background Malignant mesothelioma (MM) is an exceedingly rare tumor with poor prognosis due to the limited availability of effective treatment. Immunotherapy has emerged as a novel treatment approach for MM, but less than 40% of the patients
Externí odkaz:
https://doaj.org/article/a00e107ea4c34cb6b6184bb6f19b75c4
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The adaptive immune system generates a diverse array of B-cell receptors through the processes of V(D)J recombination and somatic hypermutation. B-cell receptors that bind to an antigen will undergo clonal expansion, creating a Darwinian evolutionary
Externí odkaz:
https://doaj.org/article/ce8d1bf9630242b0b0db4949dda4065b
Autor:
Vikram S. Pothuri, Graham D. Hogg, Leah Conant, Nicholas Borcherding, C. Alston James, Jacqueline Mudd, Greg Williams, Yongwoo David Seo, William G. Hawkins, Venu G. Pillarisetty, David G. DeNardo, Ryan C. Fields
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
Pancreatic ductal adenocarcinoma (PDAC) is a lethal malignancy that is refractory to immune checkpoint inhibitor therapy. However, intratumoral T-cell infiltration correlates with improved overall survival (OS). Herein, we characterized the diversity
Externí odkaz:
https://doaj.org/article/020545a544174e6986a7dd89b240e669
Autor:
Raneesh Ramarapu, Judit M. Wulcan, Haiyang Chang, Peter F. Moore, William Vernau, Stefan M. Keller
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionThe domestic cat (Felis catus) is a valued companion animal and a model for virally induced cancers and immunodeficiencies. However, species-specific limitations such as a scarcity of immune cell markers constrain our ability to resolve i
Externí odkaz:
https://doaj.org/article/f0b91dfbbe624e66a4b88a1a10bd40f1
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
PurposeColorectal cancer (CRC) is a leading cause of cancer-related mortality worldwide, with lymph node (LN) metastasis playing a pivotal role in disease progression. This study aimed to explore the T-cell receptor (TCR) repertoire among CRC patient
Externí odkaz:
https://doaj.org/article/7eff9d2f3eed444b9741f1f9c09daefb
Autor:
Sergey Sennikov, Marina Volynets, Saleh Alrhmoun, Roman Perik-Zavodskii, Olga Perik-Zavodskaia, Marina Fisher, Julia Lopatnikova, Julia Shevchenko, Kirill Nazarov, Julia Philippova, Alaa Alsalloum, Vasily Kurilin, Alexander Silkov
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionAdoptive cell therapy using TCR-engineered T-cells is one of the most effective strategies against tumor cells. The TCR T-cell approach has been well tested against a variety of blood neoplasms but is yet to be deeply tested against solid
Externí odkaz:
https://doaj.org/article/433d45dbd46f482299d490a3b9a17848
Autor:
Goh Ohji, Yohei Funakoshi, Kimikazu Yakushijin, Takaji Matsutani, Tomoki Sasaki, Takahiro Kusakabe, Sakuya Matsumoto, Taiji Koyama, Yoshiaki Nagatani, Keiji Kurata, Shiro Kimbara, Naomi Kiyota, Hironobu Minami
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
A monovalent Omicron XBB.1.5 mRNA RBD analogue vaccine, MAFB-7256a (DS-5670d), was newly developed and approved in Japan in the Spring of 2024 for the prevention of COVID-19. However, clinical efficacy data for this vaccine are currently lacking. We
Externí odkaz:
https://doaj.org/article/59a011b3f9d04db7af323572148f920d