Zobrazeno 1 - 10
of 2 598
pro vyhledávání: '"Receptor interaction"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract To select the core target (RAB13) in sepsis patients’ peripheral blood and investigate its molecular functions and possible mechanisms. The peripheral blood of sepsis patients (n = 21) and healthy individuals (n = 9) within 24 h after admi
Externí odkaz:
https://doaj.org/article/3e63861e581044e699c2668e31bd3a80
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-12 (2024)
Abstract Background Metabolite-associated cell communications play critical roles in maintaining human biological function. However, most existing tools and resources focus only on ligand-receptor interaction pairs where both partners are proteinaceo
Externí odkaz:
https://doaj.org/article/238994059a9c404e8d39cfee072cfa0d
Publikováno v:
Journal of Traditional and Complementary Medicine, Vol 14, Iss 2, Pp 135-147 (2024)
Background and Aim: Xuefu Zhuyu decoction (XZD), a traditional Chinese medicinal formula, was firstly recorded in the Qing dynasty of ancient China and previously demonstrated to ameliorate hepatic steatosis. In the present study, the effects of XZD
Externí odkaz:
https://doaj.org/article/9f942400ae054ced8e10c1babffe6402
Autor:
Qingyong Chen, Dongqing Wang, Zhipeng Chen, Liqiang Lin, Qiang Shao, Han Zhang, Peng Li, Huaiqing Lv
Publikováno v:
Heliyon, Vol 10, Iss 18, Pp e37738- (2024)
Objective: To analyze and validate differential genes in the cytokine-cytokine receptor interaction CCRI pathway in laryngeal squamous cell carcinoma (LSCC) using bioinformatics and Mendelian randomization (MR) to find potential biomarkers for LSCC.
Externí odkaz:
https://doaj.org/article/e7344ad96446436e86b34283852b0a65
Autor:
Fateme Yazdani, Negar Mottaghi-Dastjerdi, Behzad Shahbazi, Khadijeh Ahmadi, Abozar Ghorbani, Mohammad Soltany-Rezaee-Rad, Hamed Montazeri, Farzane Khoshdel, Pietro Hiram Guzzi
Publikováno v:
Heliyon, Vol 10, Iss 18, Pp e37451- (2024)
Introduction: Esophageal Cancer (EC) ranks among the most common malignancies worldwide. Most EC patients acquire drug resistance to chemotherapy either intrinsically or acquired after T-DM1 treatment, which shows that increasing or decreasing the ex
Externí odkaz:
https://doaj.org/article/d215ae60545a489d91b29722cabbf741
Autor:
Yancheng Lai, Xiaole Lu, Yankai Liao, Pei Ouyang, Hai Wang, Xian Zhang, Guanglong Huang, Songtao Qi, Yaomin Li
Publikováno v:
Genes and Diseases, Vol 11, Iss 2, Pp 874-889 (2024)
Glioblastoma (GBM) is the most common intrinsic and aggressive primary brain tumor in adults, with a median survival of approximately 15 months. GBM heterogeneity is considered responsible for the treatment resistance and unfavorable prognosis. Prone
Externí odkaz:
https://doaj.org/article/6c4a8cd8dd684b6c96fc58b3b5060b77
Publikováno v:
Royal Society Open Science, Vol 11, Iss 6 (2024)
Aposematic animals rely on diverse secondary metabolites for defence. Various hypotheses, such as competition, life history and multifunctionality, have been posited to explain defence variability and diversity. We investigate the compound selectivit
Externí odkaz:
https://doaj.org/article/f8238c8014df448999b5e0c3198734b2
Autor:
Zhen Huang, Enjie Xu, Xiaolong Ma, Yongjie Wang, Jiazhuang Zhu, Kunpeng Zhu, Jianping Hu, Chunlin Zhang
Publikováno v:
Translational Oncology, Vol 44, Iss , Pp 101937- (2024)
Background: Soft tissue sarcoma, a malignant tumor arising from mesenchymal tissues with poor prognosis. 5′-Nucleotidase Domain Containing 2 (NT5DC2) is a novel oncogene, and the precise involvement of NT5DC2 in soft tissue sarcoma were still undef
Externí odkaz:
https://doaj.org/article/9b73ff0519354b33baa61807b02301cc
Autor:
Atefeh Lafzi, Costanza Borrelli, Simona Baghai Sain, Karsten Bach, Jonas A Kretz, Kristina Handler, Daniel Regan-Komito, Xenia Ficht, Andreas Frei, Andreas Moor
Publikováno v:
Molecular Systems Biology, Vol 20, Iss 2, Pp 98-119 (2024)
Abstract Sequencing-based spatial transcriptomics (ST) methods allow unbiased capturing of RNA molecules at barcoded spots, charting the distribution and localization of cell types and transcripts across a tissue. While the coarse resolution of these
Externí odkaz:
https://doaj.org/article/1622b8f5debc4d0a97fb157237705827
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
IntroductionLeishmaniasis comprises a complex group of diseases caused by protozoan parasites from the Leishmania genus, presenting a significant threat to human health. Infection starts by the release into the skin of metacyclic promastigote (MP) fo
Externí odkaz:
https://doaj.org/article/78acb6cea7c8431aa3719f91dcfa4eb7