Zobrazeno 1 - 10
of 27 649
pro vyhledávání: '"Receptor binding"'
Autor:
Hajarossadat Ghaderi, Alireza Shoari, Shima Salehi, Ayda Hassanzadeh Eskafi, Mahdi Habibi-Anbouhi, Reza Ahangari Cohan, Reza Moazzami, Mahdi Behdani
Publikováno v:
Research in Pharmaceutical Sciences, Vol 19, Iss 5, Pp 500-508 (2024)
Background and purpose: SARS-CoV-2 causes a severe respiratory disease known as COVID-19 and is responsible for a global viral pandemic. The SARS-CoV-2 receptor binding domain (RBD) is located on the spike protein, which identifies and binds to the a
Externí odkaz:
https://doaj.org/article/543d2629e3c24bbd84fcc59782f1f084
Autor:
Elena Gurrieri, Giulia Carradori, Michela Roccuzzo, Michael Pancher, Daniele Peroni, Romina Belli, Caterina Trevisan, Michela Notarangelo, Wen-Qiu Huang, Agata S. A. Carreira, Alessandro Quattrone, Guido Jenster, Timo L. M. Ten Hagen, Vito Giuseppe D’Agostino
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-19 (2024)
Abstract Background Extracellular vesicles (EVs) are cell-secreted particles conceived as natural vehicles for intercellular communication. The capacity to entrap heterogeneous molecular cargoes and target specific cell populations through EV functio
Externí odkaz:
https://doaj.org/article/f77acac84bd9414abd92b0f3f19993d5
Autor:
T. A. Ivashchenko, Ya. O. Romanenko, A. S. Kartseva, M. V. Silkina, M. A. Mar’in, A. E. Khlyntseva, N. A. Zeninskaya, I. G. Shemyakin, V. V. Firstova
Publikováno v:
Проблемы особо опасных инфекций, Vol 0, Iss 3, Pp 111-117 (2024)
The aim of the work was to evaluate the ability of monoclonal antibodies to inhibit the interaction of the receptor binding domain (RBD) in S protein of SARS-CoV-2 virus variants, Wuhan-Hu-1 and BQ 1.1, with the angiotensin-converting receptor 2 (ACE
Externí odkaz:
https://doaj.org/article/47abd4b9f6f641cf80ab4fc14a4f8dcd
Publikováno v:
Journal of Cheminformatics, Vol 16, Iss 1, Pp 1-19 (2024)
Abstract Nuclear receptors (NRs) play a crucial role as biological targets in drug discovery. However, determining which compounds can act as endocrine disruptors and modulate the function of NRs with a reduced amount of candidate drugs is a challeng
Externí odkaz:
https://doaj.org/article/c22421c89d3a4596ba148a105dceb718
Autor:
Haotian Yang, Meiqi Sun, He Qiu, Huiling Xu, Zhuofan Deng, Han Gu, Nan Wang, Liuyang Du, Fushan Shi, Jiyong Zhou, Fang He
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Background Porcine reproductive and respiratory syndrome virus (PRRSV) is a prevalent swine pathogen, which has caused adverse impact on the global swine industry for almost 30 years. However, due to the immune suppression caused by the viru
Externí odkaz:
https://doaj.org/article/4df6b05944594b4b8ffb6ece2c835e99
Autor:
Deepika Rathore, Preeti Chauhan, Anvesh Bonagiri, Lekha Gandhi, Deepti Maisnam, Ramesh Kumar, Anupama T. Row, M.M. Kesavulu, Musturi Venkataramana
Publikováno v:
Heliyon, Vol 10, Iss 21, Pp e39941- (2024)
Severe acute respiratory coronavirus-2 (SARS-CoV-2) emerged in 2019 as a new virus and caused worldwide outbreaks, quickly turning into a pandemic disease called coronavirus disease-19 (COVID-19). All the existing methodologies were used for developi
Externí odkaz:
https://doaj.org/article/e71d27430e554dda8019804c78bf4233
Autor:
René Zeiss, Carlos Schönfeldt-Lecuona, Bernhard J. Connemann, Susanne Hafner, Maximilian Gahr
Publikováno v:
Frontiers in Psychiatry, Vol 15 (2024)
IntroductionAntipsychotic psychopharmacotherapy is associated with the risk of drug-induced liver injury (DILI). However, understanding specific risk factors remains challenging due to limited data. This study investigates the relationship between re
Externí odkaz:
https://doaj.org/article/47f2012549e1460f822d887a0d0428d0
Autor:
Long V. Pham, Alexander P. Underwood, Alekxander Binderup, Ulrik Fahnøe, Carlota Fernandez-Antunez, Blanca Lopez-Mendez, Line Abildgaard Ryberg, Andrea Galli, Christina Sølund, Nina Weis, Santseharay Ramirez, Jens Bukh
Publikováno v:
Emerging Microbes and Infections (2024)
The evolution of SARS-CoV-2 has led to the emergence of numerous variants of concern (VOCs), marked by changes in the viral spike glycoprotein, the primary target for neutralising antibody (nAb) responses. Emerging VOCs, particularly omicron sub-line
Externí odkaz:
https://doaj.org/article/a92a700b014849119526b7299e799525
Autor:
Chao Wang, Shiwei Wang, Shisong Jing, Yuan Zeng, Lili Yang, Yongqi Mu, Zixuan Ding, Yuqin Song, Yanmei Sun, Gang Zhang, Dawei Wei, Ming Li, Yingfei Ma, Haijian Zhou, Linhuan Wu, Jie Feng
Publikováno v:
Advanced Science, Vol 11, Iss 33, Pp n/a-n/a (2024)
Abstract Klebsiella pneumoniae, a major clinical pathogen known for causing severe infections, is attracting heightened attention due to its escalating antibiotic resistance. Phages are emerging as a promising alternative to antibiotics; however, the
Externí odkaz:
https://doaj.org/article/f7d272e4ccca439498b1227d3dd99130
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Nanobodies, single-domain antibodies derived from variable domain of camelid or shark heavy-chain antibodies, have unique properties with small size, strong binding affinity, easy construction in versatile formats, high neutralizing activity
Externí odkaz:
https://doaj.org/article/c3c3ed73ac5947cf9132d496789c4125