Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Receptor Tyrosine Kinase Gene"'
Autor:
Sumantra Chatterjee, Aravinda Chakravarti, Kameko M. Karasaki, Lauren E. Fries, Ashish Kapoor
Publikováno v:
Genome Research. 31:2199-2208
The major genetic risk factors for Hirschsprung disease (HSCR) are three common polymorphisms within cis-regulatory elements (CREs) of the receptor tyrosine kinase gene RET, which reduce its expression during enteric nervous system (ENS) development.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96ad644260c76a84ce3458c74b18a8d9
https://doi.org/10.1101/gr.275667.121
https://doi.org/10.1101/gr.275667.121
Autor:
Robert W. Ricciotti, Yajuan J. Liu, Christopher D.M. Fletcher, Yu Wu, Wenjing Wang, Eleanor Y. Chen, Jeffrey Yeh, Jose G. Mantilla
Publikováno v:
Modern Pathology. 34:1373-1383
Translocations involving FN1 have been described in a variety of neoplasms that share the presence of a cartilage matrix and may also contain a variable extent of calcification. Fusions of FN1 to FGFR1 or FGFR2 have been reported in nine soft tissue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebdcdb2c178048b82eedd4c87036ff7b
https://doi.org/10.1038/s41379-021-00786-x
https://doi.org/10.1038/s41379-021-00786-x
Publikováno v:
Journal of Managed Care & Specialty Pharmacy. 26:981-986
BACKGROUND: Larotrectinib and entrectinib are FDA-approved therapies for patients with non-small cell lung cancer (NSCLC) with neurotrophic receptor tyrosine kinase gene fusion (TRK fusion-positive...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1fe4b491e9bcc9ac4c234e263ce065f
https://doi.org/10.18553/jmcp.2020.20045
https://doi.org/10.18553/jmcp.2020.20045
Publikováno v:
JMA Journal
RET (REarranged during Transfection)is activated by DNA rearrangement of the 3′ fragment of the receptor tyrosine kinase gene, namely, RET proto-oncogene, with the 5′ fragment of various genes with putative dimerization domains, such as a coiled
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25c4ee38e543fd1e6134fee7e522642a
https://doi.org/10.31662/jmaj.2020-0021
https://doi.org/10.31662/jmaj.2020-0021
Autor:
Gaye Ulubay, Akin Ozturk, Ozge Aydin Guclu, Murat Kavas, Ülkü Yılmaz, Pinar Celik, Mehmet Karadag, Nilgün Yılmaz Demirci, Berna Komurcuoglu, Adil Zamani, Ufuk Yilmaz, Tuba Inal Cengiz, Irem Serifoglu, Pınar Akın Kabalak, Dursun Alizoroglu, Senay Yilmaz, Selma Metintaş, Suna Kavurgacı, Sedat Altin, Muzaffer Metintas, Gulsah Gunluoglu, Erdal In, Meftun Unsal, Tuğçe Şahin Özdemirel, Özgür Batum, Asude Aksoy, Yurdanur Erdogan, Berna Akıncı Özyürek, Derya Kızılgöz, Guntulu Ak
Publikováno v:
Journal of occupational and environmental medicine. 63(3)
Objective: The aim of this study is to investigate the effect of asbestos exposure on cancer-driver mutations. Methods: Between January 2014 and September 2018, epidermal growth factor receptor (EGFR), anaplastic lymphoma receptor tyrosine kinase (AL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bd5f10731aea1c9e24224574ebcc103
https://pubmed.ncbi.nlm.nih.gov/33399308
https://pubmed.ncbi.nlm.nih.gov/33399308
Autor:
Jose G. Mantilla, Christopher D.M. Fletcher, Robert W. Ricciotti, Yu Wu, Jeffrey Yeh, Eleanor Y. Chen, Yajuan J. Liu, Wenjing Wang
Translocations involving FN1 have been described in a variety of neoplasms, which share the presence of cartilage matrix and a variable extent of calcification. Fusions of FN1 to FGFR1 or FGFR2 have been reported in nine soft tissue chondromas, mostl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d85c67a4bb7ae55562303e16d0945be
https://doi.org/10.1101/2020.09.01.20186379
https://doi.org/10.1101/2020.09.01.20186379
Autor:
Yoon-Jee Chae, Jong Soon Kang, Kyeong-Ryoon Lee, Yoo-Kyung Song, Song-Hee Chae, Tae-Sung Koo, Jae Young Lee, Min Ju Kim
Publikováno v:
Journal of Analytical Science and Technology, Vol 11, Iss 1, Pp 1-9 (2020)
Larotrectinib is an orally administered drug and the first and only selective pan-tropomyosin receptor kinase (TRK) inhibitor in clinical development to treat cancer patients harboring a neurotrophic receptor tyrosine kinase gene fusion. In this stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::931e63afc5955f5235b810840dd80cad
https://doi.org/10.1186/s40543-020-00219-5
https://doi.org/10.1186/s40543-020-00219-5
Publikováno v:
Frontiers in Pediatrics
Frontiers in Pediatrics, Vol 8 (2020)
Frontiers in Pediatrics, Vol 8 (2020)
This was a Chinese neonatal congenital myasthenic syndromes case caused by muscle skeletal receptor tyrosine kinase gene mutations, which have not been recorded in the Human Gene Mutation Database. The newborn girl had refractory respiratory failure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00056247a3971a0545d96ff62384c0f2
http://europepmc.org/articles/PMC7176811
http://europepmc.org/articles/PMC7176811
Intrinsic and Extrinsic Regulation of PD-L2 Expression in Oncogene-Driven Non–Small Cell Lung Cancer
Autor:
Jiro Fujita, Yoichi Nakanishi, Naoki Kubo, Isamu Okamoto, Koichi Azuma, Daisuke Shibahara, Kentaro Tanaka, Keiichi Ota, Eiji Iwama, Taishi Harada
Publikováno v:
Journal of Thoracic Oncology. 13:926-937
Introduction The interaction of programmed cell death ligand 2 (PD-L2) with programmed cell death 1 is implicated in tumor immune escape. The regulation of PD-L2 expression in tumor cells has remained unclear, however. We here examined intrinsic and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::067d1def4e11f84ad724c671c1a0a27d
https://doi.org/10.1016/j.jtho.2018.03.012
https://doi.org/10.1016/j.jtho.2018.03.012
Autor:
Paolo Gallipoli, Brian J. P. Huntly
Publikováno v:
Clinical Cancer Research. 25:460-462
The presence of internal tandem duplications (ITD) in the FLT3 receptor tyrosine kinase gene have long been known to confer a poor prognosis in patients with acute myeloid leukemia. Now, specific structural features of the ITDs are also suggested to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d2b316dd309be655ba67ea75f42ac94
https://doi.org/10.1158/1078-0432.ccr-18-3146
https://doi.org/10.1158/1078-0432.ccr-18-3146