Výsledky vyhledávání - "Receptor Tyrosine Kinase Gene"

Akademický článek

Case report: targeted therapy of malignant pleural mesothelioma with anaplastic lymphoma kinase receptor tyrosine kinase gene fusion mutation by crizotinib

Autor: Yufeng Wu, Yuhua Zhao, Limeng Yu, Ruilin Wang, Wen Feng, Yingxi Wu, Lili Wang, Haiyang Chen, Zhen He, Qiming Wang

Publikováno v: Journal of International Medical Research, Vol 52 (2024)

Malignant mesothelioma is a rare highly invasive tumour originating from the mesothelial cells of the pleura, peritoneum and pericardium. Malignant pleural mesothelioma (MPM) is the most common type in all malignant mesothelioma. The onset of MPM is

Externí odkaz: https://doaj.org/article/3589690e8ff448adbdf7108d76d39a0e

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Akademický článek

DNA hypomethylator phenotype reprograms glutamatergic network in receptor tyrosine kinase gene-mutated glioblastoma

Autor: Mio Harachi, Kenta Masui, Erika Shimizu, Kumiko Murakami, Hiromi Onizuka, Yoshihiro Muragaki, Takakazu Kawamata, Hisako Nakayama, Mariko Miyata, Takashi Komori, Webster K. Cavenee, Paul S. Mischel, Atsushi Kurata, Noriyuki Shibata

Publikováno v: Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-17 (2024)

Abstract DNA methylation is crucial for chromatin structure and gene expression and its aberrancies, including the global “hypomethylator phenotype”, are associated with cancer. Here we show that an underlying mechanism for this phenotype in the

Externí odkaz: https://doaj.org/article/59ba976a12834ee782df85c5cc6333ba

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