Výsledky vyhledávání - "Receptor, Epidermal Growth Factor/genetics"

Presence of an oligodendroglioma-like component in newly diagnosed glioblastoma identifies a pathogenetically heterogeneous subgroup and lacks prognostic value: central pathology review of the EORTC_26981/NCIC_CE.3 trial

Autor: Mathilde C.M. Kouwenhoven, Karima Mokhtari, René-Olivier Mirimanoff, Marie-France Hamou, Christian Hartmann, Danielle Martinet, Pieter Wesseling, Roger Stupp, A. von Deimling, M. J. van den Bent, Michael Weller, N Besuchet Schmutz, Wanyu L. Lambiv, Robert-Charles Janzer, Thierry Gorlia, Annie-Claire Diserens, Monika E. Hegi, Pierre Bady, Warren P. Mason

Publikováno v: Acta Neuropathologica, 123(6), 841-852. Springer Verlag
Acta Neuropathologica, 123, 841-52
Acta Neuropathologica, 123(6), 841-852. Springer-Verlag
Hegi, M E, Janzer, R C, Lambiv, W L, Gorlia, T, Kouwenhoven, M C, Hartmann, C, von Deimling, A, Martinet, D, Besuchet Schmutz, N, Diserens, A C, Hamou, M F, Bady, P, Weller, M, van den Bent, M J, Mason, W P, Mirimanoff, R O, Stupp, R, Mokhtari, K & Wesseling, P 2012, ' Presence of an oligodendroglioma-like component in newly diagnosed glioblastoma identifies a pathogenetically heterogeneous subgroup and lacks prognostic value: central pathology review of the EORTC_26981/NCIC_CE.3 trial ', Acta Neuropathologica, vol. 123, no. 6, pp. 841-852 . https://doi.org/10.1007/s00401-011-0938-4
Acta Neuropathologica, 123, 6, pp. 841-52
Acta neuropathologica
Acta Neuropathologica, vol. 123, no. 6, pp. 841-852

Item does not contain fulltext Glioblastoma (GBM) is a morphologically heterogeneous tumor type with a median survival of only 15 months in clinical trial populations. However, survival varies greatly among patients. As part of a central pathology re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1a5a1d3c56b8ef520162e875697e9dd
https://hdl.handle.net/2066/109138

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Evaluation of the prognostic and predictive value of HER family mRNA expression in high-risk early breast cancer: A Hellenic Cooperative Oncology Group (HeCOG) study

Autor: T. Economopoulos, Helena Linardou, George C. Zografos, E. Briasoulis, George Fountzilas, Eleni Timotheadou, E. Razis, Meletios A. Dimopoulos, Ralph M. Wirtz, Angelos Koutras, H. P. Kalofonos, Helen Gogas, Gerassimos Aravantinos, D.G. Pectasides, Konstantine T. Kalogeras, Pavlos Papakostas, C. Christodoulou, Urania Dafni

Publikováno v: British Journal of Cancer

The aim of the study was to evaluate the prognostic ability of the transcriptional profiling of the HER family genes in early breast cancer, as well as to investigate the predictive value of HER2 mRNA expression for adjuvant treatment with paclitaxel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c175b4bda0afd522815f7cbeda39129
https://doi.org/10.1038/sj.bjc.6604769

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Epidermal growth factor receptor overexpression is common and not correlated to gene copy number in ependymoma

Autor: Manfred Westphal, Markus Glatzel, Carsten Friedrich, Christian Bernreuther, Ronald Simon, André O. von Bueren, Diego Sepulveda-Falla, Larissa Kolevatova, Leander van den Boom, Tobias Grob

Publikováno v: Child's Nervous System, Vol. 32, No 2 (2016) pp. 281-90

The aim of this study was to investigate the epidermal growth factor receptor (EGFR) status in ependymoma specimens, as there is a need for new prognostic and druggable targets in this disease. Ependymomas (WHO grade II, n = 40; WHO grade III, n = 15

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95e736afa605a01f39bd79d97ee80b35
https://pubmed.ncbi.nlm.nih.gov/26686534

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Akademický článek

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Epidermal Growth Factor Family and Renal Cell Carcinoma: Expression and Prognostic Impact

Autor: Stefan Riess, Ioannis D. Bassukas, Jobst Dammrich, G. Hofmockel

Publikováno v: European Urology. 31:478-484

OBJECTIVE: Expression and prognostic impact of some exponents of the epidermal growth factor (EGF) family in renal cell carcinoma (RCC) were examined. MATERIALS AND METHODS: EGF, transforming growth factor-alpha (TGF-alpha), EGF receptor (EGF-R), and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b390dff248856eb5cc56c736d7d0a1e3
https://doi.org/10.1159/000474510

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[The role of KRAS gene mutation testing in colorectal cancer--a predictive biomarker of response to EGFR inhibitors therapy]

Autor: Ivana Rako, Jasminka Jakić-Razumović, Domagoj Caban, Jadranka Sertić, Darko Katalinić, Hilda Golem, Stjepko Pleština

Publikováno v: Liječnički vjesnik
Volume 133
Issue 11-12

Aktivacija onkogena KRAS značajna je u kolorektalnoj karcinogenezi, a prisutnost KRAS-mutacije može se dokazati u više od 30% uzoraka kolorektalnog karcinoma (CRC). Među novijim lijekovima za liječenje metastatskog CRC-a jesu i pripravci koji sa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::0e25fe4d49406b05bc2fd85604993fc2
https://pubmed.ncbi.nlm.nih.gov/22329297

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Lack of EGFR-activating mutations in European patients with triple-negative breast cancer could emphasise geographic and ethnic variations in breast cancer mutation profiles

Autor: Frédéric Bibeau, Frédéric Fina, William Jacot, Gilles Romieu, Pierre-Jean Lamy, Romain Senal, Simon Thezenas, Evelyne Lopez-Crapez

Publikováno v: Breast Cancer Research : BCR
Breast Cancer Research, vol. 13, no. 6, pp. R133

INTRODUCTION: Triple-negative breast cancers (TNBCs) are characterised by lack of expression of hormone receptors and epidermal growth factor receptor 2 (HER-2). As they frequently express epidermal growth factor receptors (EGFRs), anti-EGFR therapie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1376dfda418ab987363d7989b12961f9
https://doi.org/10.1186/bcr3079

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Association of eGFR-Related Loci Identified by GWAS with Incident CKD and ESRD

Publikováno v: PLoS genetics, vol 7, iss 9
PLoS Genetics
Plos Genetics, vol. 7, no. 9, pp. e1002292
Scopus-Elsevier
PLoS Genetics, Vol 7, Iss 9, p e1002292 (2011)
PLoS Genetics (print), 7(9). Public Library of Science

Family studies suggest a genetic component to the etiology of chronic kidney disease (CKD) and end stage renal disease (ESRD). Previously, we identified 16 loci for eGFR in genome-wide association studies, but the associations of these single nucleot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaea58ee7ed26840388e1e31699ea29c
https://escholarship.org/uc/item/2gp960sb

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Thérapies ciblées du cancer pulmonaire: tests moléculaires à partir d'échantillons cytologiques

Autor: Pusztaszeri, Marc, Pache, J-C, Mach, Nicolas, Gasche-Soccal, Paola Marina Alessandra, Mckee, Thomas Alexander

Publikováno v: Revue médicale suisse, Vol. 7, No 303 (2011) pp. 1486-90

Important advances in lung cancer treatment have been made over the last decade. Several drugs designed to target molecular pathways involved in cancer-cell growth and survival have been shown to be effective in a selected fraction (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1400::f47bdf1b616622eff5d429d7cc497a40
https://archive-ouverte.unige.ch/unige:25540

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