RNA-seq transcriptomic profiling of TGF-β2-exposed human trabecular meshwork explants: Advancing insights beyond conventional cell culture models

Autor: Buffault, J., Reboussin, É., Blond, F., Guillonneau, X., Bastelica, P., Kessal, K., Akkurt Arslan, M., Melik-Parsadaniantz, S., Réaux-le Goazigo, A., Labbé, A., Brignole-Baudouin, F., Baudouin, C.

Publikováno v: In Experimental Cell Research 1 October 2024 442(2)

Evaluation of Rho kinase inhibitor effects on neuroprotection and neuroinflammation in an ex-vivo retinal explant model.

Autor: Reboussin É; INSERM UMR 968, CNRS UMR 7210, Institut de la Vision, IHU FOReSIGHT, Sorbonne Université UM80, 75012, Paris, France., Bastelica P; INSERM UMR 968, CNRS UMR 7210, Institut de la Vision, IHU FOReSIGHT, Sorbonne Université UM80, 75012, Paris, France.; INSERM-DHOS CIC 1423, IHU FOReSIGHT, Quinze-Vingts National Ophthalmology Hospital, 75012, Paris, France.; Faculty of Pharmacy of Paris, University Paris Cité, 75006, Paris, France., Benmessabih I; INSERM UMR 968, CNRS UMR 7210, Institut de la Vision, IHU FOReSIGHT, Sorbonne Université UM80, 75012, Paris, France., Cordovilla A; INSERM UMR 968, CNRS UMR 7210, Institut de la Vision, IHU FOReSIGHT, Sorbonne Université UM80, 75012, Paris, France., Delarasse C; INSERM UMR 968, CNRS UMR 7210, Institut de la Vision, IHU FOReSIGHT, Sorbonne Université UM80, 75012, Paris, France., Réaux-Le Goazigo A; INSERM UMR 968, CNRS UMR 7210, Institut de la Vision, IHU FOReSIGHT, Sorbonne Université UM80, 75012, Paris, France., Brignole-Baudouin F; INSERM UMR 968, CNRS UMR 7210, Institut de la Vision, IHU FOReSIGHT, Sorbonne Université UM80, 75012, Paris, France.; Laboratoire, Quinze-Vingts National Ophthalmology Hospital, 75012, Paris, France.; INSERM-DHOS CIC 1423, IHU FOReSIGHT, Quinze-Vingts National Ophthalmology Hospital, 75012, Paris, France.; Faculty of Pharmacy of Paris, University Paris Cité, 75006, Paris, France., Olmière C; Laboratoires THEA, Clermont-Ferrand, France., Baudouin C; INSERM UMR 968, CNRS UMR 7210, Institut de la Vision, IHU FOReSIGHT, Sorbonne Université UM80, 75012, Paris, France.; INSERM-DHOS CIC 1423, IHU FOReSIGHT, Quinze-Vingts National Ophthalmology Hospital, 75012, Paris, France.; Department of Ophthalmology III, Quinze-Vingts National Ophthalmology Hospital, IHU FOReSIGHT, 75012, Paris, France.; Department of Ophthalmology, Ambroise Paré Hospital, AP-HP, UVSQ, Paris Saclay University, 91190, Gif-sur-Yvette, France., Buffault J; INSERM UMR 968, CNRS UMR 7210, Institut de la Vision, IHU FOReSIGHT, Sorbonne Université UM80, 75012, Paris, France.; INSERM-DHOS CIC 1423, IHU FOReSIGHT, Quinze-Vingts National Ophthalmology Hospital, 75012, Paris, France.; Department of Ophthalmology III, Quinze-Vingts National Ophthalmology Hospital, IHU FOReSIGHT, 75012, Paris, France.; Department of Ophthalmology, Ambroise Paré Hospital, AP-HP, UVSQ, Paris Saclay University, 91190, Gif-sur-Yvette, France., Mélik Parsadaniantz S; INSERM UMR 968, CNRS UMR 7210, Institut de la Vision, IHU FOReSIGHT, Sorbonne Université UM80, 75012, Paris, France. stephane.melik-parsadaniantz@inserm.fr.

Publikováno v: Acta neuropathologica communications [Acta Neuropathol Commun] 2024 Sep 14; Vol. 12 (1), pp. 150. Date of Electronic Publication: 2024 Sep 14.

The Dual Effect of Rho-Kinase Inhibition on Trabecular Meshwork Cells Cytoskeleton and Extracellular Matrix in an In Vitro Model of Glaucoma.

Autor: Buffault J; Department of Ophthalmology III, Quinze-Vingts National Ophthalmology Hospital, IHU Foresight, 75012 Paris, France.; Institut de la Vision, Sorbonne Université, INSERM, CNRS, IHU Foresight, 75012 Paris, France.; Department of Ophthalmology, Ambroise Paré Hospital, APHP, Université de Paris Saclay, 92100 Boulogne-Billancourt, France., Brignole-Baudouin F; Institut de la Vision, Sorbonne Université, INSERM, CNRS, IHU Foresight, 75012 Paris, France.; Department of Biology, CHNO des Quinze-Vingts, IHU Foresight, 75012 Paris, France., Reboussin É; Institut de la Vision, Sorbonne Université, INSERM, CNRS, IHU Foresight, 75012 Paris, France., Kessal K; Institut de la Vision, Sorbonne Université, INSERM, CNRS, IHU Foresight, 75012 Paris, France., Labbé A; Department of Ophthalmology III, Quinze-Vingts National Ophthalmology Hospital, IHU Foresight, 75012 Paris, France.; Institut de la Vision, Sorbonne Université, INSERM, CNRS, IHU Foresight, 75012 Paris, France.; Department of Ophthalmology, Ambroise Paré Hospital, APHP, Université de Paris Saclay, 92100 Boulogne-Billancourt, France., Mélik Parsadaniantz S; Institut de la Vision, Sorbonne Université, INSERM, CNRS, IHU Foresight, 75012 Paris, France., Baudouin C; Department of Ophthalmology III, Quinze-Vingts National Ophthalmology Hospital, IHU Foresight, 75012 Paris, France.; Institut de la Vision, Sorbonne Université, INSERM, CNRS, IHU Foresight, 75012 Paris, France.; Department of Ophthalmology, Ambroise Paré Hospital, APHP, Université de Paris Saclay, 92100 Boulogne-Billancourt, France.

Publikováno v: Journal of clinical medicine [J Clin Med] 2022 Feb 15; Vol. 11 (4). Date of Electronic Publication: 2022 Feb 15.

Longmu Anshen prescription alleviates anxiety behavior in CRS mice by regulating polarization of microglia in medial prefrontal cortex.

Autor: PENG Xiaoming^1,2, DING Xiaohua^2,3, ZHANG Zhenwen¹, ZHAO Jianjun², TANG Ke¹

Publikováno v: Chinese Journal of Immunology. Nov2024, Vol. 40 Issue 11, p2316-2321. 6p.

AAV-NDI1 Therapy Provides Significant Benefit to Murine and Cellular Models of Glaucoma.

Autor: Millington-Ward, Sophia¹ (AUTHOR) palfia@tcd.ie, Palfi, Arpad¹ (AUTHOR) shortac@tcd.ie, Shortall, Ciara¹ (AUTHOR) lafinneg@tcd.ie, Finnegan, Laura K.¹ (AUTHOR) bargrofe@tcd.ie, Bargroff, Ethan¹ (AUTHOR) ipost@tcd.ie, Post, Iris J. M.¹ (AUTHOR) pfkenna@tcd.ie, Maguire, John² (AUTHOR) john.maguire@olchc.ie, Irnaten, Mustapha³ (AUTHOR) mustapha.irnaten2@ucd.ie, O′Brien, Colm³ (AUTHOR) cobrien@mater.ie, Kenna, Paul F.^1,2 (AUTHOR) gjfarrar@tcd.ie, Chadderton, Naomi¹ (AUTHOR), Farrar, G. Jane¹ (AUTHOR)

Publikováno v: International Journal of Molecular Sciences. Aug2024, Vol. 25 Issue 16, p8876. 17p.