Single B cell transcriptomics identifies multiple isotypes of broadly neutralizing antibodies against flaviviruses.

Autor: Lubow J; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America., Levoir LM; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America., Ralph DK; Computational Biology Program, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America., Belmont L; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America.; Molecular and Cellular Biology Graduate Program, University of Washington, Seattle, Washington, United States of America., Contreras M; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America., Cartwright-Acar CH; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America., Kikawa C; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America.; Department of Genome Sciences, University of Washington, Seattle, Washington, United States of America.; Medical Scientist Training Program, University of Washington, Seattle, Washington, United States of America., Kannan S; Integral Molecular, Inc., Philadelphia, Pennsylvania, United States of America., Davidson E; Integral Molecular, Inc., Philadelphia, Pennsylvania, United States of America., Duran V; Division of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, California, United States of America.; Chan Zuckerberg Biohub, San Francisco, California, United States of America., Rebellon-Sanchez DE; Clinical Research Center, Fundación Valle del Lili, Cali, Colombia., Sanz AM; Clinical Research Center, Fundación Valle del Lili, Cali, Colombia., Rosso F; Clinical Research Center, Fundación Valle del Lili, Cali, Colombia.; Department of Internal Medicine, Division of Infectious Diseases, Fundación Valle del Lili, Cali, Colombia., Doranz BJ; Integral Molecular, Inc., Philadelphia, Pennsylvania, United States of America., Einav S; Division of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, California, United States of America.; Chan Zuckerberg Biohub, San Francisco, California, United States of America.; Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, California, United States of America., Matsen Iv FA; Computational Biology Program, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America.; Department of Genome Sciences, University of Washington, Seattle, Washington, United States of America.; Department of Statistics, University of Washington, Seattle, Washington, United States of America.; Howard Hughes Medical Institute, Seattle, Washington, United States of America., Goo L; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, United States of America.

Publikováno v: PLoS pathogens [PLoS Pathog] 2023 Oct 09; Vol. 19 (10), pp. e1011722. Date of Electronic Publication: 2023 Oct 09 (Print Publication: 2023).