Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Rebekka Pohl"'
Autor:
Elisabeth M. Haberl, Rebekka Pohl, Lisa Rein-Fischboeck, Marcus Höring, Sabrina Krautbauer, Gerhard Liebisch, Christa Buechler
Publikováno v:
Lipids in Health and Disease, Vol 20, Iss 1, Pp 1-14 (2021)
Abstract Background Dysregulated lipid metabolism is critically involved in the development of hepatocellular carcinoma (HCC). The respective metabolic pathways affected in HCC can be identified using suitable experimental models. Mice injected with
Externí odkaz:
https://doaj.org/article/a2daa2f4b735488e839bf7f0e2e6a0ca
Autor:
Elisabeth M. Haberl, Rebekka Pohl, Lisa Rein-Fischboeck, Marcus Höring, Sabrina Krautbauer, Gerhard Liebisch, Christa Buechler
Publikováno v:
Lipids in Health and Disease, Vol 19, Iss 1, Pp 1-13 (2020)
Abstract Background Emerging data support a role for lipids in non-alcoholic steatohepatitis (NASH) and hepatocellular carcinoma (HCC) in humans. With experimental models such data can be challenged or validated. Mice fed a low-methionine, choline-de
Externí odkaz:
https://doaj.org/article/01e35dc814194b9c9975abe304d63673
Autor:
Lisa Rein-Fischboeck, Elisabeth M. Haberl, Rebekka Pohl, Susanne Feder, Gerhard Liebisch, Sabrina Krautbauer, Christa Buechler
Publikováno v:
Lipids in Health and Disease, Vol 18, Iss 1, Pp 1-12 (2019)
Abstract Background Non-alcoholic steatohepatitis (NASH) is a common disease and feeding mice a methionine-choline-deficient (MCD) diet is a frequently used model to study its pathophysiology. Genetic and environmental factors influence NASH developm
Externí odkaz:
https://doaj.org/article/733a0ae484b2428db8e19413d40e3c7f
Autor:
Rebekka Pohl, Susanne Feder, Elisabeth M. Haberl, Lisa Rein-Fischboeck, Thomas S. Weiss, Marlen Spirk, Astrid Bruckmann, Nichole McMullen, Christopher J. Sinal, Christa Buechler
Publikováno v:
Biomedicines, Vol 10, Iss 1, p 132 (2022)
Non-alcoholic steatohepatitis (NASH) is marked by macrophage infiltration and inflammation. Chemerin is a chemoattractant protein and is abundant in hepatocytes. The aim of this study was to gain insight into the role of hepatocyte-produced prochemer
Externí odkaz:
https://doaj.org/article/539de5e026b348d78767ce25dfe19292
Autor:
Elisabeth M. Haberl, Susanne Feder, Rebekka Pohl, Lisa Rein-Fischboeck, Kerstin Dürholz, Laura Eichelberger, Josef Wanninger, Thomas S. Weiss, Christa Buechler
Publikováno v:
Cancers, Vol 12, Iss 10, p 2967 (2020)
Chemerin is protective in experimental models of hepatocellular carcinoma (HCC). Noteworthy, chemerin mRNA and protein were reduced in HCC tissues of Asian patients with mostly hepatitis B disease etiology. The current study nevertheless showed that
Externí odkaz:
https://doaj.org/article/a967ebd98c294f518d881d9420bde212
Autor:
Elisabeth M. Haberl, Rebekka Pohl, Lisa Rein-Fischboeck, Susanne Feder, Christopher J. Sinal, Astrid Bruckmann, Marcus Hoering, Sabrina Krautbauer, Gerhard Liebisch, Christa Buechler
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 1, p 252 (2019)
The tumor inhibitory potential of the highly active chemerin-156 isoform was described in orthotopic models of hepatocellular carcinoma (HCC). The majority of HCC arises in the fibrotic liver, which was not reproduced in these studies. Here, a potent
Externí odkaz:
https://doaj.org/article/5231eb410c3d4558bf2f870c79c88398
Autor:
Josef Wanninger, Gerhard Liebisch, Kristina Eisinger, Markus Neumeier, Charalampos Aslanidis, Lisa Voggenreiter, Rebekka Pohl, Thomas S. Weiss, Sabrina Krautbauer, Christa Buechler
Publikováno v:
Metabolites, Vol 4, Iss 2, Pp 394-407 (2014)
Adiponectin (APN) exerts multiple beneficial effects in obesity and protects from liver injury. Different APN isoforms circulate in serum, and here, the effect of low molecular weight (LMW) and higher molecular weight (HMW) APN on primary human hepat
Externí odkaz:
https://doaj.org/article/6b6f88d9e88a4b8dba9dac021a30af3a
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 3, p 476 (2017)
Inflammation is a complex response of the body to exogenous and endogenous insults. Chronic and systemic diseases are attributed to uncontrolled inflammation. Molecules involved in the initiation of inflammation are very well studied while pathways r
Externí odkaz:
https://doaj.org/article/489af9ef9d2c42eea9c4c796ca3f9033
Autor:
Maximilian Neumann, Elisabeth M. Meier, Lisa Rein-Fischboeck, Sabrina Krautbauer, Kristina Eisinger, Charalampos Aslanidis, Rebekka Pohl, Thomas S. Weiss, Christa Buechler
Publikováno v:
International Journal of Molecular Sciences, Vol 17, Iss 8, p 1335 (2016)
The chemokine-like receptor 1 (CMKLR1) ligands resolvin E1 and chemerin are known to modulate inflammatory response. The progression of non-alcoholic fatty liver disease (NAFLD) to non-alcoholic steatohepatitis (NASH) is associated with inflammation.
Externí odkaz:
https://doaj.org/article/2877002d8d0b46cf90e175147216d4cf
Autor:
Lisa Rein-Fischboeck, Rebekka Pohl, Elisabeth M. Haberl, Wolfgang Mages, Philipp Girke, Gerhard Liebisch, Sabrina Krautbauer, Christa Buechler
Publikováno v:
Gene. 859:147209