Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Rebekka Karlowitz"'
Autor:
Lisa Kowald, Jens Roedig, Rebekka Karlowitz, Kristina Wagner, Sonja Smith, Thomas Juretschke, Petra Beli, Stefan Müller, Sjoerd J. L. van Wijk
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract Ubiquitin-specific peptidase 22 (USP22) is a deubiquitinating enzyme (DUB) that underlies tumorigenicity, proliferation, cell death and differentiation through deubiquitination of histone and non-histone targets. Ubiquitination determines st
Externí odkaz:
https://doaj.org/article/0fc6c043461f4dadbb7ba5930e2dcbc7
Autor:
Rebekka Karlowitz, Megan L. Stanifer, Jens Roedig, Geoffroy Andrieux, Denisa Bojkova, Marco Bechtel, Sonja Smith, Lisa Kowald, Ralf Schubert, Melanie Boerries, Jindrich Cinatl, Steeve Boulant, Sjoerd J. L. van Wijk
Publikováno v:
Cell Death and Disease, Vol 13, Iss 8, Pp 1-14 (2022)
Abstract Pattern recognition receptors (PRRs) and interferons (IFNs) serve as essential antiviral defense against SARS-CoV-2, the causative agent of the COVID-19 pandemic. Type III IFNs (IFN-λ) exhibit cell-type specific and long-lasting functions i
Externí odkaz:
https://doaj.org/article/e0cff6daeb78475a8d5002c6e431347e
Publikováno v:
Cell Death and Disease, Vol 12, Iss 9, Pp 1-11 (2021)
Abstract Pancreatic cancer (PC) still remains a major cause of cancer-related death worldwide and alternative treatments are urgently required. A common problem of PC is the development of resistance against apoptosis that limits therapeutic success.
Externí odkaz:
https://doaj.org/article/46184b2232014f7b9c11fe4d86ca3713
Surviving death: emerging concepts of RIPK3 and MLKL ubiquitination in the regulation of necroptosis
Autor:
Sjoerd J L van Wijk, Rebekka Karlowitz
Publikováno v:
The FEBS journalReferences.
Lytic forms of programmed cell death, like necroptosis, are characterised by cell rupture and the release of cellular contents, often provoking inflammatory responses. In the recent years, necroptosis has been shown to play important roles in human d
Publikováno v:
Viszeralmedizin 2021 Gemeinsame Jahrestagung Deutsche Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS), Sektion Endoskopie der DGVS, Deutsche Gesellschaft für Allgemein und Viszeralchirurgie (DGAV).
Autor:
Petra Beli, Lisa Kowald, Jens Roedig, Rebekka Karlowitz, Behnaz Ahangarian Abhari, Sjoerd J L van Wijk, Heiko Roedig, Simone Fulda, Thomas Juretschke
Publikováno v:
EMBO Reports
Dynamic control of ubiquitination by deubiquitinating enzymes is essential for almost all biological processes. Ubiquitin‐specific peptidase 22 (USP22) is part of the SAGA complex and catalyzes the removal of mono‐ubiquitination from histones H2A