Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Rebekka Bauer"'
Autor:
Rebekka Bauer, Sofie Patrizia Meyer, Rebecca Raue, Megan A. Palmer, Vanesa Maria Guerrero Ruiz, Giulia Cardamone, Silvia Rösser, Milou Heffels, Fabian Roesmann, Alexander Wilhelm, Dieter Lütjohann, Kathi Zarnack, Dominik Christian Fuhrmann, Marek Widera, Tobias Schmid, Bernhard Brüne
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Hypoxia contributes to numerous pathophysiological conditions including inflammation-associated diseases. We characterized the impact of hypoxia on the immunometabolic cross-talk between cholesterol and interferon (IFN) responses. Specifically, hypox
Externí odkaz:
https://doaj.org/article/0529142dc6c74d528346fa922d05bbcf
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
The importance of biologically active lipid mediators, such as prostanoids, leukotrienes, and specialized pro-resolving mediators, in the regulation of inflammation is well established. While the relevance of cholesterol in the context of atheroscler
Externí odkaz:
https://doaj.org/article/0c39f9799ec84d92b1da50906e1d4c3f
Autor:
Peter Rappl, Silvia Rösser, Patrick Maul, Rebekka Bauer, Arnaud Huard, Yannick Schreiber, Dominique Thomas, Gerd Geisslinger, Per-Johan Jakobsson, Andreas Weigert, Bernhard Brüne, Tobias Schmid
Publikováno v:
Cell Death and Disease, Vol 12, Iss 2, Pp 1-10 (2021)
Abstract Despite the progress to understand inflammatory reactions, mechanisms causing their resolution remain poorly understood. Prostanoids, especially prostaglandin E2 (PGE2), are well-characterized mediators of inflammation. PGE2 is produced in a
Externí odkaz:
https://doaj.org/article/82e45cbb0c5e4c0696246dff61defdd3
Autor:
Rebecca Raue, Ann-Christin Frank, Dominik C. Fuhrmann, Patricia de la Cruz-Ojeda, Silvia Rösser, Rebekka Bauer, Giulia Cardamone, Andreas Weigert, Shahzad Nawaz Syed, Tobias Schmid, Bernhard Brüne
Publikováno v:
Biology, Vol 11, Iss 3, p 349 (2022)
Macrophages constitute a major part of the tumor-infiltrating immune cells. Within the tumor microenvironment, they acquire an alternatively activated, tumor-supporting phenotype. Factors released by tumor cells are crucial for the recruitment of tum
Externí odkaz:
https://doaj.org/article/726f9ca323114c959940d409c4cf44ea
Autor:
Brüne, Rebekka Bauer, Sofie Patrizia Meyer, Karolina Anna Kloss, Vanesa Maria Guerrero Ruiz, Samira Reuscher, You Zhou, Dominik Christian Fuhrmann, Kathi Zarnack, Tobias Schmid, Bernhard
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 10; Pages: 5824
Previous studies towards reduced oxygen availability have mostly focused on changes in total mRNA expression, neglecting underlying transcriptional and post-transcriptional events. Therefore, we generated a comprehensive overview of hypoxia-induced c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::63dfe5fc71ab01b2a35134410a5a5513
Autor:
Rebekka, Bauer, Sofie Patrizia, Meyer, Karolina Anna, Kloss, Vanesa Maria, Guerrero Ruiz, Samira, Reuscher, You, Zhou, Dominik Christian, Fuhrmann, Kathi, Zarnack, Tobias, Schmid, Bernhard, Brüne
Publikováno v:
International journal of molecular sciences. 23(10)
Previous studies towards reduced oxygen availability have mostly focused on changes in total mRNA expression, neglecting underlying transcriptional and post-transcriptional events. Therefore, we generated a comprehensive overview of hypoxia-induced c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e76f563da28a81d39c3deabb0a8fbcfb
https://pubmed.ncbi.nlm.nih.gov/35628634
https://pubmed.ncbi.nlm.nih.gov/35628634
Autor:
Ingo Ebersberger, Annika F Fink, Arpit Jain, Dominik C. Fuhrmann, Rebekka Bauer, Catherine Olesch, Tobias Schmid, Rosa M Susen, Bernhard Brüne, Nathalie Dehne
Publikováno v:
Molecular Carcinogenesis. 58:2127-2138
In solid tumors, tumor-associated macrophages (TAMs) commonly accumulate within hypoxic areas. Adaptations to such environments evoke transcriptional changes by the hypoxia-inducible factors (HIFs). While HIF-1α is ubiquitously expressed, HIF-2α ap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81cee8cf6f361f541a4c6d815017a00f
https://doi.org/10.1002/mc.23103
https://doi.org/10.1002/mc.23103
Autor:
Rebekka Bauer, Ersin Gül, Beat Christen, V Miguelangel Cuenca, Shinichi Sunagawa, Leanid Laganenka, Franziska Besser, Julia A. Vorholt, Laura Heeb, Steffen Porwollik, Philipp J. Keller, Bidong D. Nguyen, Joel Rüthi, Susanne Meile, Johannes Hartl, Lea Fuchs, Michael McClelland, Pau Pérez Escriva, Wolf-Dietrich Hardt, Matthias Christen, Uwe Sauer, Céline Margot, Céline Fetz, Markus Furter
Publikováno v:
Cell host & microbe, vol 27, iss 6
Cell Host & Microbe, 27 (6)
Cell Host & Microbe, 27 (6)
Summary Initial enteropathogen growth in the microbiota-colonized gut is poorly understood. Salmonella Typhimurium is metabolically adaptable and can harvest energy by anaerobic respiration using microbiota-derived hydrogen (H2) as an electron donor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe4b9f45ac7dbebb44c5cb3f229ef37e
https://escholarship.org/uc/item/7890x0bt
https://escholarship.org/uc/item/7890x0bt
Autor:
Bernhard Brüne, Anja Urbschat, Andreas Weigert, Klaus Zwicker, Christina Mertens, Rebekka Bauer, Arnaud Huard, Julia K. Meier, Matthias Schnetz, Frederik Roos, Sofia Winslow, Michaela Jung, Claudia Rehwald, Patrick C. Baer
Publikováno v:
Rehwald, C, Schnetz, M, Urbschat, A, Mertens, C, Meier, J K, Bauer, R, Baer, P, Winslow, S, Roos, F C, Zwicker, K, Huard, A, Weigert, A, Brüne, B & Jung, M 2020, ' The iron load of lipocalin-2 (LCN-2) defines its pro-tumour function in clear-cell renal cell carcinoma ', British Journal of Cancer, vol. 122, no. 3, pp. 421-433 . https://doi.org/10.1038/s41416-019-0655-7
British Journal of Cancer
British Journal of Cancer
Background We aimed at clarifying the role of lipocalin-2 (LCN-2) in clear-cell renal cell carcinoma (ccRCC). Since LCN-2 was recently identified as a novel iron transporter, we explored its iron load as a decisive factor in conferring its biological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d501a31f2d05f2974674562b6b2fa251
https://publica.fraunhofer.de/handle/publica/262870
https://publica.fraunhofer.de/handle/publica/262870
Publikováno v:
Pharmacological Research. 120:146-156
Iron is an essential element for virtually all organisms. It facilitates cell proliferation and growth but also contributes to major hallmarks of cancer such as tumor initiation, growth, and metastasis. Often, iron handling of tumor cells is disturbe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68d96bb315e71c7972430ecdc9773cbc
https://doi.org/10.1016/j.phrs.2017.03.018
https://doi.org/10.1016/j.phrs.2017.03.018