Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Rebekka, Wehner"'
Autor:
Johanna Kirchner, Ioana Plesca, Rebecca Rothe, Antonia Resag, Steffen Löck, Iva Benešová, Luise Rupp, Annett Linge, Rebekka Wehner, Mechthild Krause, Marc Schmitz
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Head and neck squamous cell carcinoma (HNSCC) is one of the most common tumor entities worldwide, with human papillomavirus (HPV) infection contributing to cancer development. Conventional therapies achieve only limited efficiency, especially in recu
Externí odkaz:
https://doaj.org/article/2da60e4d39b345af92e2abb592f98e57
Autor:
Liliia Ibneeva, Sumeet Pal Singh, Anupam Sinha, Sema Elif Eski, Rebekka Wehner, Luise Rupp, Iryna Kovtun, Juan Alberto Pérez-Valencia, Alexander Gerbaulet, Susanne Reinhardt, Manja Wobus, Malte von Bonin, Jaime Sancho, Frances Lund, Andreas Dahl, Marc Schmitz, Martin Bornhäuser, Triantafyllos Chavakis, Ben Wielockx, Tatyana Grinenko
Publikováno v:
PLoS Biology, Vol 22, Iss 2, p e3002517 (2024)
A subpopulation of deeply quiescent, so-called dormant hematopoietic stem cells (dHSCs) resides at the top of the hematopoietic hierarchy and serves as a reserve pool for HSCs. The state of dormancy protects the HSC pool from exhaustion throughout li
Externí odkaz:
https://doaj.org/article/6e6a2cac4f004ac1b93ef75582908b4f
Autor:
Luise Rupp, Antonia Resag, Vlatko Potkrajcic, Verena Warm, Rebekka Wehner, Korinna Jöhrens, Hans Bösmüller, Franziska Eckert, Marc Schmitz
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Soft tissue sarcomas (STS) form a heterogeneous group of tumors sharing a mesenchymal origin. Despite good local control of the disease, the occurrence of distant metastases often limits survival of STS patients with localized, high-risk tumors of th
Externí odkaz:
https://doaj.org/article/3c5c3e09dada472eb245b3ff508ceec3
Autor:
Torben Mentrup, Anna Yamina Stumpff-Niggemann, Nadja Leinung, Christine Schlosser, Katja Schubert, Rebekka Wehner, Antje Tunger, Valentin Schatz, Patrick Neubert, Ann-Christine Gradtke, Janina Wolf, Stefan Rose-John, Paul Saftig, Alexander Dalpke, Jonathan Jantsch, Marc Schmitz, Regina Fluhrer, Ilse D. Jacobsen, Bernd Schröder
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Dectin-1 is a critical component of the innate sensing repertoire which is involved in pattern based recognition of fungal pathogens. Here the authors show that intramembrane proteolysis is involved in the regulation of the antifungal host response b
Externí odkaz:
https://doaj.org/article/f2acefb3574e4b9da6fd801ea20dcfc5
Autor:
Claudia Arndt, Antje Tunger, Rebekka Wehner, Rebecca Rothe, Eleni Kourtellari, Stephanie Luttosch, Katharina Hannemann, Stefanie Koristka, Liliana R. Loureiro, Anja Feldmann, Torsten Tonn, Theresa Link, Jan Dominik Kuhlmann, Pauline Wimberger, Michael Philipp Bachmann, Marc Schmitz
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
The cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitor palbociclib is an emerging cancer therapeutic that just recently gained Food and Drug Administration approval for treatment of estrogen receptor (ER)-positive, human epidermal growth factor recep
Externí odkaz:
https://doaj.org/article/d050e2b4207a49ff823ba99d4383286d
Autor:
Thomas Krüger, Rebekka Wehner, Maik Herbig, Martin Kräter, Michael Kramer, Jan Moritz Middeke, Friedrich Stölzel, Catrin List, Katharina Egger-Heidrich, Raphael Teipel, Uta Oelschlägel, Martin Wermke, Helena Jambor, Manja Wobus, Johannes Schetelig, Korinna Jöhrens, Torsten Tonn, Julien Subburayalu, Marc Schmitz, Martin Bornhauser, Malte von Bonin
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Functional impairment of the bone marrow (BM) niche has been suggested as a major reason for prolonged cytopenia and secondary graft failure after allogeneic hematopoietic cell transplantation (alloHCT). Because mesenchymal stromal cells (MSCs) serve
Externí odkaz:
https://doaj.org/article/992e9a44ebef4b9ba25024701532295d
Autor:
Hans-Georg Rammensee, Karl-Heinz Wiesmüller, P. Anoop Chandran, Henning Zelba, Elisa Rusch, Cécile Gouttefangeas, Daniel J. Kowalewski, Moreno Di Marco, Sebastian P. Haen, Juliane S. Walz, Yamel Cardona Gloria, Johanna Bödder, Jill-Marie Schertel, Antje Tunger, Luise Müller, Maximilian Kießler, Rebekka Wehner, Marc Schmitz, Meike Jakobi, Nicole Schneiderhan-Marra, Reinhild Klein, Karoline Laske, Kerstin Artzner, Linus Backert, Heiko Schuster, Johannes Schwenck, Alexander N. R. Weber, Bernd J. Pichler, Manfred Kneilling, Christian la Fougère, Stephan Forchhammer, Gisela Metzler, Jürgen Bauer, Benjamin Weide, Wilfried Schippert, Stefan Stevanović, Markus W. Löffler
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-18 (2019)
Abstract Background We previously showed that the bacterial lipopeptide Pam3Cys-Ser-Ser, meanwhile established as a toll-like receptor (TLR) 1/2 ligand, acts as a strong adjuvant for the induction of virus specific CD8+ T cells in mice, when covalent
Externí odkaz:
https://doaj.org/article/cc3a16412b7c49e5953df66f2cd4dccd
Autor:
Ulrich Sommer, Jürgen Weitz, Daniela Aust, Maximilian Kießler, Ioana Plesca, Rebekka Wehner, Friederike Wilczkowski, Luise Müller, Antje Tunger, Xixi Lai, Anke Rentsch, Adrian M Seifert, Lena Seifert, Michael Bachmann, Martin Bornhäuser, Gustavo Baretton, Marc Schmitz
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 3 (2021)
Background Plasmacytoid dendritic cells (pDCs) play a key role in the induction and maintenance of antitumor immunity. Conversely, they can act as tolerogenic DCs by inhibiting tumor-directed immune responses. Therefore, pDCs may profoundly influence
Externí odkaz:
https://doaj.org/article/47849b5e9eeb4ac59685008f84a1679c
Autor:
Luise Müller, Antje Tunger, Manja Wobus, Malte von Bonin, Russell Towers, Martin Bornhäuser, Francesco Dazzi, Rebekka Wehner, Marc Schmitz
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Mesenchymal stromal cells (MSCs) are characterized by an extraordinary capacity to modulate the phenotype and functional properties of various immune cells that play an essential role in the pathogenesis of inflammatory disorders. Thus, MSCs efficien
Externí odkaz:
https://doaj.org/article/1e1d2d3802e6401c9a6a73cd97374963
Autor:
Ioana Plesca, Iva Benešová, Carolin Beer, Ulrich Sommer, Luise Müller, Rebekka Wehner, Max Heiduk, Daniela Aust, Gustavo Baretton, Michael P Bachmann, Anja Feldmann, Jürgen Weitz, Lena Seifert, Adrian M Seifert, Marc Schmitz
Publikováno v:
Cancers, Vol 14, Iss 5, p 1216 (2022)
Dendritic cells (DCs) play a key role in the orchestration of antitumor immunity. Activated DCs efficiently enhance antitumor effects mediated by natural killer cells and T lymphocytes. Conversely, tolerogenic DCs essentially contribute to an immunos
Externí odkaz:
https://doaj.org/article/e5a4820d9bd747be86ac1dd95b79bdde