Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Rebekka, Unland"'
Autor:
Stefan Burdach, Günther H.S. Richter, Elke Butt, Andrea Cossarizza, Agnes Görlach, Olivia Prazeres da Costa, Albert Sickmann, Urs Lewandrowski, Katharina Lohrig, Colette Zobywalski, Carsten Müller-Tidow, Rebekka Unland, Frauke Neff, Patricia da Silva-Buttkus, Uwe Thiel, Kristina Hauer, Stephanie Plehm, Irene Esposito, Isabel Diebold, Thomas G.P. Grunewald
PDF file - 621K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ac515f338a8df0f2b23504d350f89d9
https://doi.org/10.1158/1541-7786.22517596.v1
https://doi.org/10.1158/1541-7786.22517596.v1
Autor:
Stefan Burdach, Günther H.S. Richter, Elke Butt, Andrea Cossarizza, Agnes Görlach, Olivia Prazeres da Costa, Albert Sickmann, Urs Lewandrowski, Katharina Lohrig, Colette Zobywalski, Carsten Müller-Tidow, Rebekka Unland, Frauke Neff, Patricia da Silva-Buttkus, Uwe Thiel, Kristina Hauer, Stephanie Plehm, Irene Esposito, Isabel Diebold, Thomas G.P. Grunewald
Ewing tumors comprise the second most common type of bone-associated cancer in children and are characterized by oncogenic EWS/FLI1 fusion proteins and early metastasis. Compelling evidence suggests that elevated levels of intracellular oxidative str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01fb4ff581cd74645a62434114fb1608
https://doi.org/10.1158/1541-7786.c.6541777
https://doi.org/10.1158/1541-7786.c.6541777
Autor:
Christiane Schaefer, Amelie Tillmanns, Rebekka Unland, Carsten Müller-Tidow, Birgit Lechtape, K L Schäfer, Heribert Jürgens, Uta Dirksen, Eberhard Korsching, Jenny Potratz, Carolin Schleithoff, Philipp Berning
Publikováno v:
Molecular Oncology. 10:677-692
Receptor tyrosine kinases (RTKs) have provided molecular targets for the development of novel, prognosis‐improving agents in many cancers; however, resistances to these therapies occur. On the cellular level, one resistance mechanism is attributed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd5709bda568e81d6f65cdb7a868df10
https://doi.org/10.1016/j.molonc.2015.12.009
https://doi.org/10.1016/j.molonc.2015.12.009
Autor:
Cora Reiss, Stefan Burdach, Frauke Neff, Olivia Prazeres da Costa, Elke Butt, Uta Dirksen, Thorsten Buch, Semjon Willier, Rebekka Unland, Dirk Janik, Gunther Richter, Thomas G. P. Grunewald
Publikováno v:
Biology of the Cell. 105:535-547
Ewing's sarcoma (ES) is the second most common bone-associated malignancy in children and is driven by the fusion oncogene EWS/FLI1 and characterised by rapid growth and early metastasis. Here, we explored the role of the Zyxin-related protein thyroi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f78cda1882a46ea69c11eb207aa449e
https://doi.org/10.1111/boc.201300041
https://doi.org/10.1111/boc.201300041
Autor:
Patricia da Silva-Buttkus, Kristina Hauer, Urs Lewandrowski, Thomas G. P. Grunewald, Stephanie Plehm, Stefan Burdach, Isabel Diebold, Andrea Cossarizza, Gunther Richter, Carsten Müller-Tidow, Olivia Prazeres da Costa, Elke Butt, Uwe Thiel, Irene Esposito, Colette Zobywalski, Albert Sickmann, Rebekka Unland, Agnes Görlach, Frauke Neff, Katharina Lohrig
Publikováno v:
Molecular Cancer Research; Vol 10
Molecular Cancer Research
Mol. Cancer Res. 10, 52-65 (2012)
Molecular Cancer Research
Mol. Cancer Res. 10, 52-65 (2012)
Ewing tumors comprise the second most common type of bone-associated cancer in children and are characterized by oncogenic EWS/FLI1 fusion proteins and early metastasis. Compelling evidence suggests that elevated levels of intracellular oxidative str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c58c447fc88b70afba118bab33544b02
https://doi.org/10.1158/1541-7786.mcr-11-0524
https://doi.org/10.1158/1541-7786.mcr-11-0524
Autor:
Stefan Burdach, Carsten Müller-Tidow, Rebekka Unland, Martin S. Staege, Arndt Borkhardt, Uta Dirksen, Gunther Richter, Stephanie Plehm
Publikováno v:
Cell Cycle. 8:1991-1996
Chromatin modifications are increasingly recognized as a key mechanism in cancer. The histone methyltransferase Enhancer of Zeste, Drosophila, Homolog 2 (EZH2), the enzymatic subunit of the polycomb PRC2 complex methylates histone H3K27, thereby, med
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a27e5b58137f88047d32a0aa2f511cfa
https://doi.org/10.4161/cc.8.13.8929
https://doi.org/10.4161/cc.8.13.8929
Autor:
Simone Fulda, Rebekka Unland, Eva Wardelmann, Marc Hotfilder, Jenny Potratz, Michael C. Frühwald, Ulrike Heinicke, Uta Dirksen, Dagmar Clemens
Publikováno v:
Anti-cancer drugs. 26(8)
Ewing sarcomas (ES) are highly malignant tumors arising in bone and soft tissues. Given the poor outcome of affected patients with primary disseminated disease or at relapse, there is a clear need for new targeted therapies. The HDAC inhibitor (HDACi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92167fc77fe6912941e5c54db6cae52e
https://pubmed.ncbi.nlm.nih.gov/26053276
https://pubmed.ncbi.nlm.nih.gov/26053276
Autor:
Uta Dirksen, Christiane Borchardt, Michael C. Frühwald, Dagmar Clemens, Marcel Kool, Rebekka Unland
Publikováno v:
Anti-cancer drugs. 26(3)
Rhabdoid tumors (RTs) are highly aggressive pediatric malignancies with a rather poor prognosis. New therapeutic approaches and optimization of already established treatment protocols are urgently needed. The histone methyltransferase enhancer of zes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a17fefc9114a2340e69f77dc34c698c1
https://pubmed.ncbi.nlm.nih.gov/25415657
https://pubmed.ncbi.nlm.nih.gov/25415657
Autor:
Thomas G P, Grunewald, Semjon, Willier, Dirk, Janik, Rebekka, Unland, Cora, Reiss, Olivia, Prazeres da Costa, Thorsten, Buch, Uta, Dirksen, Günther H S, Richter, Frauke, Neff, Stefan, Burdach, Elke, Butt
Publikováno v:
Biology of the cell. 105(11)
Ewing's sarcoma (ES) is the second most common bone-associated malignancy in children and is driven by the fusion oncogene EWS/FLI1 and characterised by rapid growth and early metastasis. Here, we explored the role of the Zyxin-related protein thyroi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::71a7d615eef79bcc51d445c141392bd6
https://pubmed.ncbi.nlm.nih.gov/24033704
https://pubmed.ncbi.nlm.nih.gov/24033704
Autor:
Birigit Lechtape, Martin Hasselblatt, Jörg Mühlisch, Steven C. Clifford, Michael C. Frühwald, Sabrina Schlosser, Joachim Gerss, Jonas H. Kreth, Gunther Richter, Rebekka Unland, Kornelius Kerl, Tanja Plagemann, Nicole Farwick
Publikováno v:
Journal of neuro-oncology. 116(2)
Epigenetic alterations are common events in cancer. Using a genome wide methylation screen (Restriction Landmark Genomic Scanning-RLGS) we identified the gene for the dopamine receptor D4 (DRD4) as tumor-specific methylated. As DRD4 is involved in ea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b89941e8fcd59bfdeff90fcdc75cbfc0
https://pubmed.ncbi.nlm.nih.gov/24264533
https://pubmed.ncbi.nlm.nih.gov/24264533