Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Rebekah S. Gilbert"'
Autor:
Yoshiko Fukuyama, Daisuke Tokuhara, Shinichi Sekine, Kazuyoshi Aso, Kosuke Kataoka, Julia Davydova, Masato Yamamoto, Rebekah S Gilbert, Yuka Tokuhara, Keiko Fujihashi, Jun Kunisawa, Yoshikazu Yuki, Hiroshi Kiyono, Jerry R McGhee, Kohtaro Fujihashi
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60453 (2013)
We assessed the role of CCR5(+)/CCR6(+)/CD11b(+)/CD11c(+) dendritic cells (DCs) for induction of ovalbumin (OVA)-specific antibody (Ab) responses following mucosal immunization. Mice given nasal OVA plus an adenovirus expressing Flt3 ligand (Ad-FL) s
Externí odkaz:
https://doaj.org/article/e67de8f7dd71445d98a0c9996ed96c13
Autor:
Kosuke Kataoka, Keiko Fujihashi, Yutaka Terao, Rebekah S Gilbert, Shinichi Sekine, Ryoki Kobayashi, Yoshiko Fukuyama, Shigetada Kawabata, Kohtaro Fujihashi
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e25396 (2011)
Native cholera toxin (nCT) as a nasal adjuvant was shown to elicit increased levels of T-independent S-IgA antibody (Ab) responses through IL-5- IL-5 receptor interactions between CD4+ T cells and IgA+ B-1 B cells in murine submandibular glands (SMGs
Externí odkaz:
https://doaj.org/article/81971d897f2d44bf95fb5da06c944d96
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27501 (2011)
Our previous studies have shown that Peyer's patches (PPs) play a key role in the induction of oral tolerance. Therefore, we hypothesized that PPs are an important site for Transforming Growth Factor (TGF)-β signaling and sought to prove that this t
Externí odkaz:
https://doaj.org/article/86c2bc3b4a2a4dcbaed74b583c259ff7
Autor:
Yoshiko Fukuyama, Grace H. Moon, Julia Davydova, Kosuke Kataoka, Jonathan D. Markham, Yuka Tokuhara, Daisuke Tokuhara, K Fujihashi, Masato Yamamoto, Kohtaro Fujihashi, Rebekah S. Gilbert, Allyson R. Irwin, Shinichi Sekine
Publikováno v:
Biochemical and Biophysical Research Communications. 418:6-11
Our previous studies showed that an adenovirus (Ad) serotype 5 vector expressing Flt3 ligand (Ad-FL) as nasal adjuvant activates CD11c(+) dendritic cells (DCs) for the enhancement of antigen (Ag)-specific IgA antibody (Ab) responses. In this study, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::569c46f2ca1c4332748c6a5ad2bea508
https://doi.org/10.1016/j.bbrc.2011.12.046
https://doi.org/10.1016/j.bbrc.2011.12.046
Autor:
Shinichi Sekine, Yoshiko Fukuyama, K Fujihashi, Daisuke Tokuhara, Tatsuya Fukuiwa, Kohtaro Fujihashi, Normaiza Zamri, Hideki Asanuma, Masato Tashiro, Tetsutaro Sata, Rebekah S. Gilbert
Publikováno v:
Vaccine. 30:803-812
Since a combination of flt3 ligand plasmid (pFL) and CpG-oligodeoxynucleotides (ODN)(3) as a dendritic cell (DC)-targeting double mucosal adjuvant elicited ovalbumin-specific secretory IgA (S-IgA) antibody (Ab) responses, we examined whether this dou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f89c8a901473ea32bd4cb5fdcb615806
https://doi.org/10.1016/j.vaccine.2011.10.093
https://doi.org/10.1016/j.vaccine.2011.10.093
Autor:
Masaki Goto, Masafumi Yamamoto, Makoto Fukui, Yutaka Terao, Kohtaro Fujihashi, Tselmeg Baatarjav, Kosuke Kataoka, Shigetada Kawabata, Rebekah S. Gilbert, Hiro-O Ito
Publikováno v:
Vaccine. 29:5747-5757
Phosphorylcholine (PC) is an immunodominant epitope in some pathogens including Streptococcus pneumoniae and it is well-known that PC-specific antibodies (Abs) play a key role in the induction of protective immunity against pneumococcal infection. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35882f1d9404f86dfb0eee4c914ffa04
https://doi.org/10.1016/j.vaccine.2011.05.097
https://doi.org/10.1016/j.vaccine.2011.05.097
Autor:
Janice D. King, Yoshiko Fukuyama, David E. Briles, Ryoki Kobayashi, Susan K. Hollingshead, Kosuke Kataoka, Rebekah S. Gilbert, Kohtaro Fujihashi
Publikováno v:
The Journal of Immunology. 186:2454-2461
Our previous study showed that a combination of a plasmid-expressing Flt3 ligand (pFL) and CpG oligodeoxynucleotides (CpG ODN) as a combined nasal adjuvant elicited mucosal immune responses in aged (2-y-old) mice. In this study, we investigated wheth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54308f6e5b39db63014b1b4010302c4d
https://doi.org/10.4049/jimmunol.1002837
https://doi.org/10.4049/jimmunol.1002837
Autor:
Jerry R. McGhee, Rebekah S. Gilbert, Prosper N. Boyaka, Yuichi Kurono, Tatsuya Fukuiwa, Kosuke Kataoka, Hideaki Suzuki, Kohtaro Fujihashi, Shinichi Sekine, Ryoki Kobayashi, Arthur M. Krieg
Publikováno v:
Vaccine. 26:4849-4859
We explore cellular and molecular mechanisms of nasal adjuvant of a combination of a plasmid encoding the Flt3 ligand cDNA (pFL) and CpG oligodeoxynucleotides (CpG ODN). The double DNA adjuvant given with OVA maintained prolonged OVA-specific secreto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6487b3a17ca7299ce36840799d12051a
https://doi.org/10.1016/j.vaccine.2008.06.091
https://doi.org/10.1016/j.vaccine.2008.06.091
Autor:
Fujkuyama Y, Rebekah S. Gilbert, Kohtaro Fujihashi, Daisuke Tokuhara, Kosuke Kataoka, Hiroshi Kiyono, Yoshikazu Yuki, McGhee
Publikováno v:
Expert review of vaccines. 11(3)
To develop protective immune responses against mucosal pathogens, the delivery route and adjuvants for vaccination are important. The host, however, strives to maintain mucosal homeostasis by responding to mucosal antigens with tolerance, instead of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0c7ef4bf96bddefe4c42d761761b182
https://pubmed.ncbi.nlm.nih.gov/22380827
https://pubmed.ncbi.nlm.nih.gov/22380827
Autor:
Ryoki Kobayashi, M. Wada, John D. Ruby, Kohtaro Fujihashi, Tetsuro Kono, Masafumi Yamamoto, Yoshiko Fukuyama, Rebekah S. Gilbert, B.A. Bolerjack, Kosuke Kataoka
Precise immunological aspects of inflamed gingival mucosa remain to be elucidated in the murine experimental periodontitis model; therefore, we have characterized the mucosal immune cells in the inflamed gingiva of mice with alveolar bone reduction.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::683530bcacfa356303dc5121073c6cb1
https://europepmc.org/articles/PMC3144111/
https://europepmc.org/articles/PMC3144111/
