Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Rebekah M. Samsonraj"'
Autor:
Vitali V. Maldonado, Neel H. Patel, Emma E. Smith, C. Lowry Barnes, Michael P. Gustafson, Raj R. Rao, Rebekah M. Samsonraj
Publikováno v:
Journal of Biological Engineering, Vol 17, Iss 1, Pp 1-22 (2023)
Abstract Mesenchymal stem/stromal cells (MSCs) have been carefully examined to have tremendous potential in regenerative medicine. With their immunomodulatory and regenerative properties, MSCs have numerous applications within the clinical sector. MS
Externí odkaz:
https://doaj.org/article/91522a5e8e264204a0e3c535f236b046
Publikováno v:
Animals, Vol 14, Iss 9, p 1292 (2024)
Background: Mesenchymal stem cells (MSCs) are increasingly trialed in cellular therapy applications in humans. They can also be applied to treat a range of diseases in animals, particularly in cattle to combat inflammatory conditions and aging-associ
Externí odkaz:
https://doaj.org/article/a65668a35c32430087fc12db7757a8b7
Publikováno v:
Bone Reports, Vol 18, Iss , Pp 101674- (2023)
Mesenchymal stem cells (MSCs) derived from bone marrow can support skeletal tissue repair and regeneration owing to their self-renewing capacity, differentiation ability, and trophic functions. Bone marrow-derived MSCs undergo dramatic changes with a
Externí odkaz:
https://doaj.org/article/bfa07f337a8f4d4f9710694ad51d6cd9
Autor:
Ling Ling, Xiafei Ren, Xue Cao, Afizah Binte Mohd Hassan, Sophia Mah, Padmapriya Sathiyanathan, Raymond A.A. Smith, Clarissa L.L. Tan, Michelle Eio, Rebekah M. Samsonraj, Andre J. van Wijnen, Michael Raghunath, Victor Nurcombe, James H. Hui, Simon M. Cool
Publikováno v:
Stem Cell Reports, Vol 14, Iss 1, Pp 105-121 (2020)
Summary: Human mesenchymal stem cell (hMSC) therapy offers significant potential for osteochondral regeneration. Such applications require their ex vivo expansion in media frequently supplemented with fibroblast growth factor 2 (FGF2). Particular hep
Externí odkaz:
https://doaj.org/article/20588c373c4b42dcb4070cc8ac8229d2
Autor:
Endre Soreide, Janet M. Denbeigh, Eric A. Lewallen, Roman Thaler, Rebekah M. Samsonraj, Dakota L. Jones, Wei Xu, Dirk Larson, Lars Nordsletten, Sanjeev Kakar, Andre J. van Wijnen
Publikováno v:
BMC Musculoskeletal Disorders, Vol 20, Iss 1, Pp 1-12 (2019)
Abstract Background Injuries in the musculoskeletal system, such as tendon and ligament ruptures, are challenging to manage and often require surgical reconstructions with limited long-term success. Thus, characterizations of these tissues are urgent
Externí odkaz:
https://doaj.org/article/a39294de42e541028c5f54254f1b5623
Autor:
Clarissa L.L. Tan, Rebekah M. Samsonraj, Ling Ling, Victor Nurcombe, Padmapriya Sathiyanathan, Alexander Lezhava, Simon M. Cool, Lawrence W. Stanton
Publikováno v:
Stem Cells. 38:1124-1136
Although the application of human mesenchymal stem cells (hMSCs) to repair damaged or diseased tissues has proven relatively effective, both the donor-to-donor variability in ex vivo expansion rates and the maintenance of stemness remain a bottleneck
Autor:
Wei Xu, Rebekah M. Samsonraj, Eric A. Lewallen, Janet M. Denbeigh, Endre Soreide, Dakota L. Jones, Lars Nordsletten, Sanjeev Kakar, Roman Thaler, Andre J. van Wijnen, Dirk R. Larson
Publikováno v:
BMC Musculoskeletal Disorders, Vol 20, Iss 1, Pp 1-12 (2019)
BMC Musculoskeletal Disorders
BMC Musculoskeletal Disorders
Background Injuries in the musculoskeletal system, such as tendon and ligament ruptures, are challenging to manage and often require surgical reconstructions with limited long-term success. Thus, characterizations of these tissues are urgently needed
Publikováno v:
Current Osteoporosis Reports. 17:70-85
We review cell senescence in the context of age-related bone loss by broadly discussing aging mechanisms in bone, currently known inducers and markers of senescence, the senescence-associated secretory phenotype (SASP), and the emerging roles of sene
Autor:
Panfeng, Yu, Pengfei, Zan, Xifeng, Zhang, Hua, Qiang, Rebekah M, Samsonraj, Jiaguang, Tang, Peng, Huang
Publikováno v:
Pain physician. 24(1)
Percutaneous transforaminal endoscopic discectomy (PTED) and microendoscopic discectomy (MED) are alternative minimally invasive procedures for the treatment of symptomatic lumbar disc herniation (LDH). However, insufficient literature exists to high
Autor:
Andre J. van Wijnen, Sanjeev Kakar, Amel Dudakovic, Rebekah M. Samsonraj, Hayman Lui, Cedryck Vaquette, Janet M. Denbeigh, Simon M. Cool
Publikováno v:
Tissue Eng Part A
High concentrations of bone morphogenetic protein 2 (BMP2) in bone regeneration cause adverse events (e.g, heterotopic bone formation and acute inflammation). This study examines novel epigenetic strategies (i.e., EZH2 inhibition) for augmenting oste