Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Rebekah L. Gundry"'
Autor:
Rebekah L. Gundry, Davor Pavlovic
Publikováno v:
Journal of Molecular and Cellular Cardiology Plus, Vol 7, Iss , Pp 100058- (2024)
Externí odkaz:
https://doaj.org/article/341b88896d6e4579b60b1dbcbdd488df
Publikováno v:
iScience, Vol 25, Iss 9, Pp 105031- (2022)
Summary: Apolipoproteins, the protein component of lipoproteins, play an important role in lipid transport, lipoprotein assembly, and receptor recognition. Apolipoproteins are glycosylated and the glycan moieties play an integral role in apolipoprote
Externí odkaz:
https://doaj.org/article/391eef0ebdf54dddb53ec0548de994f7
Autor:
Subash Adhikari, Edouard C. Nice, Eric W. Deutsch, Lydie Lane, Gilbert S. Omenn, Stephen R. Pennington, Young-Ki Paik, Christopher M. Overall, Fernando J. Corrales, Ileana M. Cristea, Jennifer E. Van Eyk, Mathias Uhlén, Cecilia Lindskog, Daniel W. Chan, Amos Bairoch, James C. Waddington, Joshua L. Justice, Joshua LaBaer, Henry Rodriguez, Fuchu He, Markus Kostrzewa, Peipei Ping, Rebekah L. Gundry, Peter Stewart, Sanjeeva Srivastava, Sudhir Srivastava, Fabio C. S. Nogueira, Gilberto B. Domont, Yves Vandenbrouck, Maggie P. Y. Lam, Sara Wennersten, Juan Antonio Vizcaino, Marc Wilkins, Jochen M. Schwenk, Emma Lundberg, Nuno Bandeira, Gyorgy Marko-Varga, Susan T. Weintraub, Charles Pineau, Ulrike Kusebauch, Robert L. Moritz, Seong Beom Ahn, Magnus Palmblad, Michael P. Snyder, Ruedi Aebersold, Mark S. Baker
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
The Human Proteome Project (HPP) was launched in 2010 to enhance accurate annotation of the genome-encoded proteome. Ten years later, the HPP releases its first blueprint of the human proteome, annotating 90% of all known proteins at high-stringency
Externí odkaz:
https://doaj.org/article/bb037a5bb053476e9a3946b7578e5277
Autor:
Matthew Waas, Ranjuna Weerasekera, Erin M. Kropp, Marisol Romero-Tejeda, Ellen N. Poon, Kenneth R. Boheler, Paul W. Burridge, Rebekah L. Gundry
Publikováno v:
Stem Cell Reports, Vol 12, Iss 2, Pp 395-410 (2019)
Summary: Several protocols now support efficient differentiation of human pluripotent stem cells to cardiomyocytes (hPSC-CMs) but these still indicate line-to-line variability. As the number of studies implementing this technology expands, accurate a
Externí odkaz:
https://doaj.org/article/2f775c712d194c6d9c0295e0efc68677
Autor:
Matthew R. Medcalf, Pooja Bhadbhade, Ted R. Mikuls, James R. O’Dell, Rebekah L. Gundry, Ryan S. Funk
Publikováno v:
Metabolites, Vol 11, Iss 12, p 824 (2021)
Methotrexate (MTX) efficacy in the treatment of rheumatoid arthritis (RA) is variable and unpredictable, resulting in a need to identify biomarkers to guide drug therapy. This study evaluates changes in the plasma metabolome associated with response
Externí odkaz:
https://doaj.org/article/a65b59be9dd14d04a4415b95ee3d7621
Publikováno v:
Stem Cell Reports, Vol 7, Iss 3, Pp 543-556 (2016)
When comparing hepatic phenotypes between iPSC-derived hepatocyte-like cells from different liver disease patients, cell heterogeneity can confound interpretation. We proposed that homogeneous cell populations could be generated by fluorescence-activ
Externí odkaz:
https://doaj.org/article/8ec8211f91994a1fb2043d46d5e6faa5
Autor:
Kenneth R. Boheler, Subarna Bhattacharya, Erin M. Kropp, Sandra Chuppa, Daniel R. Riordon, Damaris Bausch-Fluck, Paul W. Burridge, Joseph C. Wu, Robert P. Wersto, Godfrey Chi Fung Chan, Sridhar Rao, Bernd Wollscheid, Rebekah L. Gundry
Publikováno v:
Stem Cell Reports, Vol 3, Iss 1, Pp 185-203 (2014)
Detailed knowledge of cell-surface proteins for isolating well-defined populations of human pluripotent stem cells (hPSCs) would significantly enhance their characterization and translational potential. Through a chemoproteomic approach, we developed
Externí odkaz:
https://doaj.org/article/4cb4d4fca3d44ea7ab17c6b73157557c
Autor:
Kenneth R. Boheler, Robert N. Joodi, Hui Qiao, Ondrej Juhasz, Amanda L. Urick, Sandra L. Chuppa, Rebekah L. Gundry, Robert P. Wersto, Rong Zhou
Publikováno v:
Stem Cells International, Vol 2011 (2011)
Pluripotent stem cells represent one promising source for cell replacement therapy in heart, but differentiating embryonic stem cell-derived cardiomyocytes (ESC-CMs) are highly heterogeneous and show a variety of maturation states. In this study, we
Externí odkaz:
https://doaj.org/article/0c51febe3a534a8692bd645299272db0
Autor:
Linda Berg Luecke, Matthew Waas, Jack Littrell, Melinda Wojtkiewicz, Chase Castro, Maria Burkovetskaya, Erin N. Schuette, Amanda Rae Buchberger, Jared M. Churko, Upendra Chalise, Michelle Waknitz, Shelby Konfrst, Roald Teuben, Justin Morrissette-McAlmon, Claudius Mahr, Daniel R. Anderson, Kenneth R. Boheler, Rebekah L. Gundry
Publikováno v:
Nature Cardiovascular Research. 2:76-95
Cardiac cell surface proteins are drug targets and useful biomarkers for discriminating among cellular phenotypes and disease states. Here we developed an analytical platform, CellSurfer, that enables quantitative cell surface proteome (surfaceome) p
Autor:
Mitra, Farnoodian, Devika, Bose, Vladimir, Khristov, Praveen Joseph, Susaimanickam, Savitri, Maddileti, Indumathi, Mariappan, Mones, Abu-Asab, Maria, Campos, Rafael, Villasmil, Qin, Wan, Arvydas, Maminishkis, David, McGaughey, Francesca, Barone, Rebekah L, Gundry, Daniel R, Riordon, Kenneth R, Boheler, Ruchi, Sharma, Kapil, Bharti
Publikováno v:
Stem Cell Reports. 17:2438-2450
Stargardt retinopathy is an inherited form of macular degeneration caused by mutations in gene ABCA4 and characterized by the accumulation of lipid-rich deposits in the retinal pigment epithelium (RPE), RPE atrophy, and photoreceptor cell death. Inad