Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Rebekah Koppenol"'
Publikováno v:
Cell Death and Disease, Vol 12, Iss 6, Pp 1-17 (2021)
Abstract Stress granules (SGs) are membraneless cell compartments formed in response to different stress stimuli, wherein translation factors, mRNAs, RNA-binding proteins (RBPs) and other proteins coalesce together. SGs assembly is crucial for cell s
Externí odkaz:
https://doaj.org/article/92cd819c6aaa4904bb1e52a2965346a5
Publikováno v:
Neural Regeneration Research, Vol 18, Iss 12, Pp 2695-2696 (2023)
Externí odkaz:
https://doaj.org/article/18a9efb147c442d28bc8a44fad05291c
Autor:
Clévio Nóbrega, André Conceição, Rafael G. Costa, Rebekah Koppenol, Raquel L. Sequeira, Ricardo Nunes, Sara Carmo-Silva, Adriana Marcelo, Carlos A. Matos, Sandrine Betuing, Jocelyne Caboche, Nathalie Cartier, Sandro Alves
Publikováno v:
BMC Research Notes, Vol 13, Iss 1, Pp 1-9 (2020)
Abstract Objective Compromised brain cholesterol turnover and altered regulation of brain cholesterol metabolism have been allied with some neurodegenerative diseases, including Huntington’s disease (HD). Following our previous studies in HD, in th
Externí odkaz:
https://doaj.org/article/34bd3c232ee348b6aee607030541dff4
Autor:
Rebekah Koppenol, André Conceição, Adriana Marcelo, Sandra Tomé, José-Miguel Côdesso, Liliana Mendonça, Luis Pereira de Almeida, Carlos Matos, Clévio Nóbrega
Polylgutamine (polyQ) diseases are a group of neurodegenerative disorders caused by abnormal expansion of CAG repeat tracts in the codifying regions of nine, otherwise unrelated, genes. While the protein products of these genes are suggested to play
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2d824972a405850a92f304bda104421
https://doi.org/10.21203/rs.3.rs-668663/v2
https://doi.org/10.21203/rs.3.rs-668663/v2
Autor:
Rebekah Koppenol, André Conceição, Inês T Afonso, Ricardo Afonso-Reis, Rafael G Costa, Sandra Tomé, Diogo Teixeira, Joana Pinto da Silva, José Miguel Côdesso, David V C Brito, Liliana Mendonça, Adriana Marcelo, Luís Pereira de Almeida, Carlos A Matos, Clévio Nóbrega
Publikováno v:
Brain : a journal of neurology.
Koppenol et al. show that overexpression of G3BP1 in cell models of SCA2 and SCA3 leads to a reduction in ataxin-2 and ataxin-3 aggregation. G3BP1 lentiviral delivery reduces motor deficits and neuropathology in preclinical models, suggesting that G3
Autor:
Clévio Nóbrega, André Conceição, Sandra Tomé, Rebekah Koppenol, Carlos A. Matos, Adriana Marcelo, Liliana Mendonça, Luís Pereira de Almeida, José-Miguel Côdesso
Polyglutamine (polyQ) diseases are a group of 9 rare neurodegenerative disorders caused by an abnormal expansion of the CAG trinucleotide in the codifying regions of the respective disease-associated gene. The trinucleotide abnormal expansion leads t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b4e55ec31f887fbcb05da3d88e1b765
https://doi.org/10.21203/rs.3.rs-668663/v1
https://doi.org/10.21203/rs.3.rs-668663/v1
Publikováno v:
Cell Death & Disease
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Cell Death and Disease, Vol 12, Iss 6, Pp 1-17 (2021)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Cell Death and Disease, Vol 12, Iss 6, Pp 1-17 (2021)
Stress granules (SGs) are membraneless cell compartments formed in response to different stress stimuli, wherein translation factors, mRNAs, RNA-binding proteins (RBPs) and other proteins coalesce together. SGs assembly is crucial for cell survival,
Autor:
Nathalie Cartier, Carlos A. Matos, André Conceição, Rebekah Koppenol, Sandro Alves, Clévio Nóbrega, Sara Carmo-Silva, Ricardo Nunes, Sandrine Betuing, Adriana Marcelo, Rafael G. Costa, Raquel L. Sequeira, Jocelyne Caboche
Publikováno v:
BMC Research Notes
BMC Research Notes, BioMed Central, 2020, 13, ⟨10.1186/s13104-020-05053-x⟩
BMC Research Notes, Vol 13, Iss 1, Pp 1-9 (2020)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
BMC Research Notes, BioMed Central, 2020, 13, ⟨10.1186/s13104-020-05053-x⟩
BMC Research Notes, Vol 13, Iss 1, Pp 1-9 (2020)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Objective Compromised brain cholesterol turnover and altered regulation of brain cholesterol metabolism have been allied with some neurodegenerative diseases, including Huntington’s disease (HD). Following our previous studies in HD, in this study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8be3e7dc85b98e3f5990a850c62e19b3
https://hal.archives-ouvertes.fr/hal-03053649/document
https://hal.archives-ouvertes.fr/hal-03053649/document
Autor:
Ana Vasconcelos-Ferreira, Filipa Brito, Liliana Mendonça, Carlos A. Matos, Luís Pereira de Almeida, Rebekah Koppenol, Clévio Nóbrega, Sara Carmo-Silva, Adriana Marcelo, João Alves-Cruzeiro
Publikováno v:
Human Molecular Genetics
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Machado-Joseph disease (MJD) is a neurodegenerative disorder caused by an abnormal expansion of citosine-adenine-guanine trinucleotide repeats in the disease-causing gene. This mutation leads to an abnormal polyglutamine tract in the protein ataxin-3
Autor:
Adriana Marcelo, Carlos A. Matos, Rebekah Koppenol, Catarina Nunes, Clévio Nóbrega, Isa Mestre
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Database: The Journal of Biological Databases and Curation
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Database: The Journal of Biological Databases and Curation
In response to different stress stimuli, cells transiently form stress granules (SGs) in order to protect themselves and re-establish homeostasis. Besides these important cellular functions, SGs are now being implicated in different human diseases, s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92ae2b940b63799b733b16e4e62857e2