Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Rebekah Kong"'
Autor:
Julie Carrard, Fiona Ratajczak, Joséphine Elsens, Catherine Leroy, Rebekah Kong, Lucie Geoffroy, Arnaud Comte, Guy Fournet, Benoît Joseph, Xiubin Li, Sylvie Moebs-Sanchez, Fabrice Lejeune
Publikováno v:
Biomedicines, Vol 11, Iss 10, p 2801 (2023)
Nonsense-mediated mRNA decay (NMD) is a quality control mechanism that degrades mRNAs carrying a premature termination codon. Its inhibition, alone or in combination with other approaches, could be exploited to develop therapies for genetic diseases
Externí odkaz:
https://doaj.org/article/05e2ba02ef9c46fb8388786117f2811b
Autor:
Catherine Leroy, Sacha Spelier, Nadège Charlene Essonghe, Virginie Poix, Rebekah Kong, Patrick Gizzi, Claire Bourban, Séverine Amand, Christine Bailly, Romain Guilbert, David Hannebique, Philippe Persoons, Gwenaëlle Arhant, Anne Prévotat, Philippe Reix, Dominique Hubert, Michèle Gérardin, Mathias Chamaillard, Natalia Prevarskaya, Sylvie Rebuffat, George Shapovalov, Jeffrey Beekman, Fabrice Lejeune
Publikováno v:
Molecular Therapy
Molecular Therapy, 2023, ⟨10.1016/j.ymthe.2023.01.014⟩
Molecular Therapy, 2023, ⟨10.1016/j.ymthe.2023.01.014⟩
International audience; Nonsense mutations are responsible for around 10% of cases of genetic diseases, including cystic fibrosis. 2,6-diaminopurine (DAP) has recently been shown to promote efficient readthrough of UGA premature stop codons. In this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc481988984698949612be12adcd5eae
https://hal.science/hal-03979419/document
https://hal.science/hal-03979419/document
Autor:
Catherine Leroy, Martine Palma, Sophie Salomé-Desnoulez, Marc Mongy, Fabrice Lejeune, Elisabeth Werkmeister, Hervé Le Hir, Rebekah Kong
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, 2021, 49 (19), pp.11022-11037. ⟨10.1093/nar/gkab882⟩
Nucleic Acids Research, Oxford University Press, 2021, 49 (19), pp.11022-11037. ⟨10.1093/nar/gkab882⟩
Nucleic Acids Research, 2021, 49 (19), pp.11022-11037. ⟨10.1093/nar/gkab882⟩
Nucleic Acids Research, Oxford University Press, 2021, 49 (19), pp.11022-11037. ⟨10.1093/nar/gkab882⟩
Nonsense-mediated mRNA decay (NMD) is a highly regulated quality control mechanism through which mRNAs harboring a premature termination codon are degraded. It is also a regulatory pathway for some genes. This mechanism is subject to various levels o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dd5383ac735a0d1c396ebaf8481a61c
https://cnrs.hal.science/hal-03423347
https://cnrs.hal.science/hal-03423347