Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Rebekah Honce"'
Autor:
Hailong Guo, Bomsoo Cho, Paul R. Hinton, Sijia He, Yongjun Yu, Ashwin Kumar Ramesh, Jwala Priyadarsini Sivaccumar, Zhiqiang Ku, Kristen Campo, Sarah Holland, Sameer Sachdeva, Christopher Mensch, Mohamed Dawod, Annalis Whitaker, Philip Eisenhauer, Allison Falcone, Rebekah Honce, Jason W. Botten, Stephen F. Carroll, Bruce A. Keyt, Andrew W. Womack, William R. Strohl, Kai Xu, Ningyan Zhang, Zhiqiang An, Sha Ha, John W. Shiver, Tong-Ming Fu
Publikováno v:
Emerging Microbes and Infections, Vol 12, Iss 2 (2023)
The capacity of SARS-CoV-2 to evolve poses challenges to conventional prevention and treatment options such as vaccination and monoclonal antibodies, as they rely on viral receptor binding domain (RBD) sequences from previous strains. Additionally, a
Externí odkaz:
https://doaj.org/article/b32daa709614466280c100d037969216
Autor:
Rebekah Honce, Jeremy Jones, Victoria A. Meliopoulos, Brandi Livingston, Bridgett Sharp, Leonardo D. Estrada, Lindsey Wang, William Caulfield, Burgess Freeman, Elena Govorkova, Stacey Schultz-Cherry
Publikováno v:
mBio, Vol 14, Iss 4 (2023)
ABSTRACT Obesity has been epidemiologically and empirically linked with more severe diseases upon influenza infection. To ameliorate severe disease, treatment with antivirals, such as the neuraminidase inhibitor oseltamivir, is suggested to begin wit
Externí odkaz:
https://doaj.org/article/0a1998aea44d44c3a86371144b0ad70c
Autor:
Katherine A. Amato, Luis A. Haddock, Katarina M. Braun, Victoria Meliopoulos, Brandi Livingston, Rebekah Honce, Grace A. Schaack, Emma Boehm, Christina A. Higgins, Gabrielle L. Barry, Katia Koelle, Stacey Schultz-Cherry, Thomas C. Friedrich, Andrew Mehle
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Transmission of influenza A viruses (IAV) between hosts and replication within host impose genetic bottlenecks, constraining viral diversity and adaptation. Here, Amato et al. perform site-specific inoculation of barcoded IAV of ferrets and track vir
Externí odkaz:
https://doaj.org/article/d3cb8e6727e14346a2d7c30f2568dc31
Autor:
Rebekah Honce, Stacey Schultz-Cherry
Publikováno v:
PLoS Pathogens, Vol 16, Iss 8, p e1008711 (2020)
Externí odkaz:
https://doaj.org/article/08437ed2c74d4ea689b34c549386553c
Autor:
Rebekah Honce, Erik A. Karlsson, Nicholas Wohlgemuth, Leonardo D. Estrada, Victoria A. Meliopoulos, Jiangwei Yao, Stacey Schultz-Cherry
Publikováno v:
mBio, Vol 11, Iss 2 (2020)
ABSTRACT Obesity is associated with increased disease severity, elevated viral titers in exhaled breath, and significantly prolonged viral shed during influenza A virus infection. Due to the mutable nature of RNA viruses, we questioned whether obesit
Externí odkaz:
https://doaj.org/article/0f8be709e91242ec8528399106fc710e
Autor:
Rebekah Honce, Stacey Schultz-Cherry
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
With the rising prevalence of obesity has come an increasing awareness of its impact on communicable disease. As a consequence of the 2009 H1N1 influenza A virus pandemic, obesity was identified for the first time as a risk factor for increased disea
Externí odkaz:
https://doaj.org/article/d1d5790735574c44829f651502a0a5e6
Autor:
Chang Wang, Rebekah Honce, Mirella Salvatore, Daniela Chow, Davide Randazzo, Jianjun Yang, Nicholas M. Twells, Lara K. Mahal, Stacey Schultz-Cherry, Elodie Ghedin
Publikováno v:
Journal of Virology.
During replication, the influenza virus generates genetically defective viruses. These are found in natural infections as part of the virus population within the infected host.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::938967a206fdacefa8664c122d51d1df
https://doi.org/10.1128/jvi.00493-23
https://doi.org/10.1128/jvi.00493-23
Autor:
Gabrielle L. Barry, Luis A. Haddock, Brandi Livingston, Andrew Mehle, Katarina M. Braun, Victoria A. Meliopoulos, Katherine A. Amato, Grace A. Schaack, Emma C. Boehm, Katia Koelle, Stacey Schultz-Cherry, Thomas C. Friedrich, Rebekah Honce, Christina A. Higgins
Publikováno v:
Nature Communications. 13
Transmission of influenza A viruses (IAV) between hosts is subject to numerous physical and biological barriers that impose genetic bottlenecks, constraining viral diversity and adaptation. The presence of bottlenecks within individual hosts and thei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c01e3e1b7d3d35a77f16de3904d2a1a
https://doi.org/10.1038/s41467-022-31147-0
https://doi.org/10.1038/s41467-022-31147-0
Autor:
Rebekah Honce, Ana Vazquez-Pagan, Brandi Livingston, Sean Cherry, Virginia Hargest, Bridgett Sharp, Lee-Ann Van de Velde, R. Chris Skinner, Paul G. Thomas, Stacey Schultz-Cherry
Persons with obesity are at higher risk for developing severe complications upon influenza virus infection making vaccination a priority. Yet, studies demonstrate vaccine responses are less effective in obese hosts. In these studies, we examined how
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85a8b55b0681a25b88f11a5a70976dbd
https://doi.org/10.1101/2022.04.16.488487
https://doi.org/10.1101/2022.04.16.488487
Publikováno v:
Future Virology. 15:441-453
Pregnant women are among the individuals at the highest risk for severe influenza virus infection. Infection of the mother during pregnancy increases the probability of adverse fetal outcomes such as small for gestational age, preterm birth and fetal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::822e94790038479538e33c5293a5b0ce
https://doi.org/10.2217/fvl-2020-0024
https://doi.org/10.2217/fvl-2020-0024