Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Rebekah Addison"'
Autor:
Aditi S. Khatpe, Rebecca Dirks, Poornima Bhat-Nakshatri, Henry Mang, Katie Batic, Sarah Swiezy, Jacob Olson, Xi Rao, Yue Wang, Hiromi Tanaka, Sheng Liu, Jun Wan, Duojiao Chen, Yunlong Liu, Fang Fang, Sandra Althouse, Emily Hulsey, Maggie M. Granatir, Rebekah Addison, Constance J. Temm, George Sandusky, Audrey Lee-Gosselin, Kenneth Nephew, Kathy D. Miller, Harikrishna Nakshatri
Publikováno v:
Cancer Research. 83:1345-1360
Study of genomic aberrations leading to immortalization of epithelial cells has been technically challenging due to the lack of isogenic models. To address this, we used healthy primary breast luminal epithelial cells of different genetic ancestry an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d80bdbe8f7e3fd859b87ba6cb6728f30
https://doi.org/10.1158/0008-5472.can-22-3667
https://doi.org/10.1158/0008-5472.can-22-3667
Autor:
Brijesh Kumar, Katie Batic, Poornima Bhat-Nakshatri, Maggie Granatir, Rebekah Addison, Megan Szymanski, Lee Ann Baldridge, Constance Temm, George Sandusky, Sandra Althouse, Anna Maria Storniolo, Harikrishna Nakshatri
Publikováno v:
Cancer Research. 83:P2-26
The biologic basis of genetic ancestry-dependent variability in disease incidence and outcome is just beginning to be explored. We recently reported enrichment of a population of ZEB1-expressing cells located adjacent to the ductal epithelial cells i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8ea1b1476e1debcdc6c7d05ca39d6c3
https://doi.org/10.1158/1538-7445.sabcs22-p2-26-08
https://doi.org/10.1158/1538-7445.sabcs22-p2-26-08
Autor:
Harikrishna Nakshatri, Kathy D. Miller, Kenneth Nephew, Audrey Lee-Gosselin, George Sandusky, Constance J. Temm, Rebekah Addison, Maggie M. Granatir, Emily Hulsey, Sandra Althouse, Fang Fang, Yunlong Liu, Duojiao Chen, Jun Wan, Sheng Liu, Hiromi Tanaka, Yue Wang, Xi Rao, Jacob Olson, Sarah Swiezy, Katie Batic, Henry Mang, Poornima Bhat-Nakshatri, Rebecca Dirks, Aditi S. Khatpe
Table S9: Results of ATAC-seq of primary and TONSL-immortalized cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aebc890399e5bfe96f54d95a43428de
https://doi.org/10.1158/0008-5472.22633261.v1
https://doi.org/10.1158/0008-5472.22633261.v1
Autor:
Harikrishna Nakshatri, Kathy D. Miller, Kenneth Nephew, Audrey Lee-Gosselin, George Sandusky, Constance J. Temm, Rebekah Addison, Maggie M. Granatir, Emily Hulsey, Sandra Althouse, Fang Fang, Yunlong Liu, Duojiao Chen, Jun Wan, Sheng Liu, Hiromi Tanaka, Yue Wang, Xi Rao, Jacob Olson, Sarah Swiezy, Katie Batic, Henry Mang, Poornima Bhat-Nakshatri, Rebecca Dirks, Aditi S. Khatpe
Study of genomic aberrations leading to immortalization of epithelial cells has been technically challenging due to the lack of isogenic models. To address this, we used healthy primary breast luminal epithelial cells of different genetic ancestry an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a02b10f9fff51b50bf5355116b3f214
https://doi.org/10.1158/0008-5472.c.6599674.v1
https://doi.org/10.1158/0008-5472.c.6599674.v1
Supplementary Data from TONSL Is an Immortalizing Oncogene and a Therapeutic Target in Breast Cancer
Autor:
Harikrishna Nakshatri, Kathy D. Miller, Kenneth Nephew, Audrey Lee-Gosselin, George Sandusky, Constance J. Temm, Rebekah Addison, Maggie M. Granatir, Emily Hulsey, Sandra Althouse, Fang Fang, Yunlong Liu, Duojiao Chen, Jun Wan, Sheng Liu, Hiromi Tanaka, Yue Wang, Xi Rao, Jacob Olson, Sarah Swiezy, Katie Batic, Henry Mang, Poornima Bhat-Nakshatri, Rebecca Dirks, Aditi S. Khatpe
Contains additional materials and methods and supplementary figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f5b3f2a2a751789590276560b96ae52
https://doi.org/10.1158/0008-5472.22633315
https://doi.org/10.1158/0008-5472.22633315
Autor:
Harikrishna Nakshatri, Kathy D. Miller, Kenneth Nephew, Audrey Lee-Gosselin, George Sandusky, Constance J. Temm, Rebekah Addison, Maggie M. Granatir, Emily Hulsey, Sandra Althouse, Fang Fang, Yunlong Liu, Duojiao Chen, Jun Wan, Sheng Liu, Hiromi Tanaka, Yue Wang, Xi Rao, Jacob Olson, Sarah Swiezy, Katie Batic, Henry Mang, Poornima Bhat-Nakshatri, Rebecca Dirks, Aditi S. Khatpe
Table S14: Genes differentially expressed in TMD-436pLKO and TMD-436shTONSL cells. Fold changes in gene expression are indicated.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52699d3aef6706dbbb0a42057607ca98
https://doi.org/10.1158/0008-5472.22633297.v1
https://doi.org/10.1158/0008-5472.22633297.v1
Autor:
Harikrishna Nakshatri, Kathy D. Miller, Kenneth Nephew, Audrey Lee-Gosselin, George Sandusky, Constance J. Temm, Rebekah Addison, Maggie M. Granatir, Emily Hulsey, Sandra Althouse, Fang Fang, Yunlong Liu, Duojiao Chen, Jun Wan, Sheng Liu, Hiromi Tanaka, Yue Wang, Xi Rao, Jacob Olson, Sarah Swiezy, Katie Batic, Henry Mang, Poornima Bhat-Nakshatri, Rebecca Dirks, Aditi S. Khatpe
Table S11: The effects of TONSL overexpression on proliferation signature of breast tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b81e9a14f5afe50bc2d526e08bc245c
https://doi.org/10.1158/0008-5472.22633306.v1
https://doi.org/10.1158/0008-5472.22633306.v1
Autor:
Harikrishna Nakshatri, Kathy D. Miller, Kenneth Nephew, Audrey Lee-Gosselin, George Sandusky, Constance J. Temm, Rebekah Addison, Maggie M. Granatir, Emily Hulsey, Sandra Althouse, Fang Fang, Yunlong Liu, Duojiao Chen, Jun Wan, Sheng Liu, Hiromi Tanaka, Yue Wang, Xi Rao, Jacob Olson, Sarah Swiezy, Katie Batic, Henry Mang, Poornima Bhat-Nakshatri, Rebecca Dirks, Aditi S. Khatpe
Table S10: Results of RNA-seq analysis of primary and TONSL-immortalized cells. Fold differences in expression are shown.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d2f4cd7bdc73c45fdfa87b7dbf081e9
https://doi.org/10.1158/0008-5472.22633309.v1
https://doi.org/10.1158/0008-5472.22633309.v1
Autor:
Harikrishna Nakshatri, Kathy D. Miller, Kenneth Nephew, Audrey Lee-Gosselin, George Sandusky, Constance J. Temm, Rebekah Addison, Maggie M. Granatir, Emily Hulsey, Sandra Althouse, Fang Fang, Yunlong Liu, Duojiao Chen, Jun Wan, Sheng Liu, Hiromi Tanaka, Yue Wang, Xi Rao, Jacob Olson, Sarah Swiezy, Katie Batic, Henry Mang, Poornima Bhat-Nakshatri, Rebecca Dirks, Aditi S. Khatpe
Table S5: Description of the patients and characteristics of their tumors (n=597)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bdd5aaa31464ffe694acb00963b1da0
https://doi.org/10.1158/0008-5472.22633279.v1
https://doi.org/10.1158/0008-5472.22633279.v1
Autor:
Harikrishna Nakshatri, Kathy D. Miller, Kenneth Nephew, Audrey Lee-Gosselin, George Sandusky, Constance J. Temm, Rebekah Addison, Maggie M. Granatir, Emily Hulsey, Sandra Althouse, Fang Fang, Yunlong Liu, Duojiao Chen, Jun Wan, Sheng Liu, Hiromi Tanaka, Yue Wang, Xi Rao, Jacob Olson, Sarah Swiezy, Katie Batic, Henry Mang, Poornima Bhat-Nakshatri, Rebecca Dirks, Aditi S. Khatpe
Table S4: Breast cancers with TONSL amplification selectively overexpress genes associated with E2F targets, G2/M checkpoint, mitotic spindle and mTORC1 pathways.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04d5b5b223dc9ad118d980fb41938e16
https://doi.org/10.1158/0008-5472.22633282
https://doi.org/10.1158/0008-5472.22633282