Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Rebecka Wombacher"'
Autor:
Elisabeth Braun, Dominik Hotter, Lennart Koepke, Fabian Zech, Rüdiger Groß, Konstantin M.J. Sparrer, Janis A. Müller, Christian K. Pfaller, Elena Heusinger, Rebecka Wombacher, Kathrin Sutter, Ulf Dittmer, Michael Winkler, Graham Simmons, Martin R. Jakobsen, Karl-Klaus Conzelmann, Stefan Pöhlmann, Jan Münch, Oliver T. Fackler, Frank Kirchhoff, Daniel Sauter
Publikováno v:
Cell Reports, Vol 27, Iss 7, Pp 2092-2104.e10 (2019)
Summary: Guanylate-binding protein (GBP) 5 is an interferon (IFN)-inducible cellular factor reducing HIV-1 infectivity by an incompletely understood mechanism. Here, we show that this activity is shared by GBP2, but not by other members of the human
Externí odkaz:
https://doaj.org/article/23fcf6a2dd424c5193317bfaa8ba1f2e
Publikováno v:
Journal of Biological Chemistry. 293:7824-7840
The HIV type 1 pathogenicity factor Nef enhances viral replication by modulating multiple host cell pathways, including tuning the activation state of infected CD4 T lymphocytes to optimize virus spread. For this, Nef inhibits anterograde transport o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c2e4d161f3fb281ddad6dbd0d39cf9f
https://doi.org/10.1074/jbc.ra118.002794
https://doi.org/10.1074/jbc.ra118.002794
Autor:
Virginia Pierini, Massimo Pizzato, Amanda J. Chase, Rebecka Wombacher, Bettina Stolp, Birthe Trautz, Oliver T. Fackler
Publikováno v:
Journal of Virology. 90:10915-10927
SERINC3 (serine incorporator 3) and SERINC5 are recently identified host cell inhibitors of HIV-1 particle infectivity that are counteracted by the viral pathogenesis factor Nef. Here we confirm that HIV-1 Nef, but not HIV-1 Vpu, antagonizes the part
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2d6f27efca41185f49c6b3b1245de45
https://doi.org/10.1128/jvi.01246-16
https://doi.org/10.1128/jvi.01246-16
Autor:
Elisabeth Braun, Dominik Hotter, Lennart Koepke, Fabian Zech, Rüdiger Groß, Konstantin M.J. Sparrer, Janis A. Müller, Christian K. Pfaller, Elena Heusinger, Rebecka Wombacher, Kathrin Sutter, Ulf Dittmer, Michael Winkler, Graham Simmons, Martin R. Jakobsen, Karl-Klaus Conzelmann, Stefan Pöhlmann, Jan Münch, Oliver T. Fackler, Frank Kirchhoff, Daniel Sauter
Publikováno v:
Braun, E, Hotter, D, Koepke, L, Zech, F, Groß, R, Sparrer, K M J, Müller, J A, Pfaller, C K, Heusinger, E, Wombacher, R, Sutter, K, Dittmer, U, Winkler, M, Simmons, G, Jakobsen, M R, Conzelmann, K-K, Pöhlmann, S, Münch, J, Fackler, O T, Kirchhoff, F & Sauter, D 2019, ' Guanylate-Binding Proteins 2 and 5 Exert Broad Antiviral Activity by Inhibiting Furin-Mediated Processing of Viral Envelope Proteins ', Cell Reports, vol. 27, no. 7, pp. 2092-2104.e10 . https://doi.org/10.1016/j.celrep.2019.04.063
Cell Reports, Vol 27, Iss 7, Pp 2092-2104.e10 (2019)
Cell Reports, Vol 27, Iss 7, Pp 2092-2104.e10 (2019)
Summary: Guanylate-binding protein (GBP) 5 is an interferon (IFN)-inducible cellular factor reducing HIV-1 infectivity by an incompletely understood mechanism. Here, we show that this activity is shared by GBP2, but not by other members of the human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ce42d3598f7f2ed441bb62c400826919
https://pubmed.ncbi.nlm.nih.gov/31091448
https://pubmed.ncbi.nlm.nih.gov/31091448
Autor:
Stefano Lazzarano, Marek Kučka, Claude Libert, Michael N. C. Fletcher, Tino Hochepied, Ronald Naumann, Paloma Medina, Rebecka Wombacher, Marc Van Montagu, Yingguang Frank Chan, Joao P. L. Castro, Joost Gribnau
Publikováno v:
Proceedings of the National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of Ame, 115(14), 3680-3685. National Academy of Sciences
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of Ame, 115(14), 3680-3685. National Academy of Sciences
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Significance How species differ from each other is a key question in biology. However, genetic mapping between species often fails because of sterile hybrid crosses. Here, we have developed a technique called in vitro recombination to circumvent bree
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aad0eeec922c65da085413314c86e9cc
Autor:
Rebecka Wombacher, Claude Libert, Marek Kučka, Joost Gribnau, Yingguang Frank Chan, Tino Hochepied, Paloma Medina, Ronald Naumann, Michael N. C. Fletcher, Stefano Lazzarano, Joao P. L. Castro
Discovering the genetic changes underlying species differences is a central goal in evolutionary genetics. However, hybrid crosses between species in mammals often suffer from hybrid sterility, greatly complicating genetic dissection of trait variati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7474eb5d9cde1e32f4fa3190f14e19e5
https://doi.org/10.1101/148486
https://doi.org/10.1101/148486
