Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Rebecca Yaworski"'
Autor:
Samantha F. Kornfeld, Sarah E. Cummings, Rebecca Yaworski, Yves De Repentigny, Sabrina Gagnon, Stephanie Zandee, Samaneh Fathi, Alexandre Prat, Rashmi Kothary
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-19 (2024)
Abstract Strategies for treating progressive multiple sclerosis (MS) remain limited. Here, we found that miR-145-5p is overabundant uniquely in chronic lesion tissues from secondary progressive MS patients. We induced both acute and chronic demyelina
Externí odkaz:
https://doaj.org/article/44c7ebcf25614e2aabf92ea59d7493d9
Autor:
Lucia Chehade, Marc-Olivier Deguise, Yves De Repentigny, Rebecca Yaworski, Ariane Beauvais, Sabrina Gagnon, Niko Hensel, Rashmi Kothary
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Spinal muscular atrophy (SMA) is a monogenic neuromuscular disease caused by low levels of the Survival Motor Neuron (SMN) protein. Motor neuron degeneration is the central hallmark of the disease. However, the SMN protein is ubiquitously expressed a
Externí odkaz:
https://doaj.org/article/7012f123c6254c638026160eccd82345
Autor:
Conor O’Dwyer, Rebecca Yaworski, Sakie Katsumura, Peyman Ghorbani, Kaelan Gobeil Odai, Julia R.C. Nunes, Nicholas D. LeBlond, Sabrin Sanjana, Tyler T.K. Smith, Shauna Han, Kaitlyn D. Margison, Tommy Alain, Masahiro Morita, Morgan D. Fullerton
Publikováno v:
Hepatology Communications, Vol 4, Iss 6, Pp 876-889 (2020)
Choline is an essential nutrient and a critical component of the membrane phospholipid phosphatidylcholine (PC), the neurotransmitter acetylcholine, while also contributing to the methylation pathway. In the liver specifically, PC is the major membra
Externí odkaz:
https://doaj.org/article/6f21bd4cf0e644f38c1cf1dba71d17bc
Autor:
Jason K Wasserman, Garth Nicholas, Rebecca Yaworski, Anne-Marie Wasserman, John M Woulfe, Gerard H Jansen, Santanu Chakraborty, Thanh B Nguyen
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123890 (2015)
Glioblastoma can occur either de novo or by the transformation of a low grade tumour; the majority of which harbor a mutation in isocitrate dehydrogenase (IDH1). Anaplastic tumours are high-grade gliomas that may represent the final step in the evolu
Externí odkaz:
https://doaj.org/article/f3e448f57cc84dd586a7b19e2c3e0c3d
Autor:
Christiano R. R. Alves, Leillani L. Ha, Rebecca Yaworski, Cicera R. Lazzarotto, Kathleen A. Christie, Aoife Reilly, Ariane Beauvais, Roman M. Doll, Demitri de la Cruz, Casey A. Maguire, Kathryn J. Swoboda, Shengdar Q. Tsai, Rashmi Kothary, Benjamin P. Kleinstiver
Spinal muscular atrophy (SMA) is a devastating neuromuscular disease caused by mutations in theSMN1gene. Despite the development of various therapies, outcomes can remain suboptimal in SMA infants and the duration of such therapies are uncertain.SMN2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4eaa7a91ed126da64d6658d42d9a9fde
https://doi.org/10.1101/2023.01.20.524978
https://doi.org/10.1101/2023.01.20.524978
Autor:
Aoife Reilly, Marc-Olivier Deguise, Ariane Beauvais, Rebecca Yaworski, Simon Thebault, Daniel R. Tessier, Vincent Tabard-Cossa, Niko Hensel, Bernard L. Schneider, Rashmi Kothary
Publikováno v:
Gene therapy. 29(9)
Spinal muscular atrophy (SMA) is a neuromuscular disease caused by loss of the SMN1 gene and low SMN protein levels. Although lower motor neurons are a primary target, there is evidence that peripheral organ defects contribute to SMA. Current SMA gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd7e0c6ba4f308147121a57a57c7d8c1
https://pubmed.ncbi.nlm.nih.gov/35462564
https://pubmed.ncbi.nlm.nih.gov/35462564
Autor:
Garth Nicholas, Anne-Marie Wasserman, John Woulfe, Jason K. Wasserman, Gerard H. Jansen, Thanh B. Nguyen, Santanu Chakraborty, Rebecca Yaworski
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123890 (2015)
PLoS ONE
PLoS ONE
Background Glioblastoma can occur either de novo or by the transformation of a low grade tumour; the majority of which harbor a mutation in isocitrate dehydrogenase (IDH1). Anaplastic tumours are high-grade gliomas that may represent the final step i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8c771cd3729f132969a99ffc2853dc3
https://doi.org/10.1371/journal.pone.0123890
https://doi.org/10.1371/journal.pone.0123890