Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Rebecca Wiegner"'
Publikováno v:
Stem Cells International, Vol 2016 (2016)
Mesenchymal stem cells (MSCs) are multipotent cells that are considered indispensable in regeneration processes after tissue trauma. MSCs are recruited to damaged areas via several chemoattractant pathways where they function as “actors” in the h
Externí odkaz:
https://doaj.org/article/2f56b49f5a4b4984b6e27fa42c3a4e84
Autor:
Stephanie Denk, Rebecca Wiegner, Felix M. Hönes, David A. C. Messerer, Peter Radermacher, Manfred Weiss, Miriam Kalbitz, Christian Ehrnthaller, Sonja Braumüller, Oscar McCook, Florian Gebhard, Sebastian Weckbach, Markus Huber-Lang
Publikováno v:
Mediators of Inflammation, Vol 2015 (2015)
Severe tissue trauma-induced systemic inflammation is often accompanied by evident or occult blood-organ barrier dysfunctions, frequently leading to multiple organ dysfunction. However, it is unknown whether specific barrier molecules are shed into t
Externí odkaz:
https://doaj.org/article/1da74cb879e64934ba1d27c17859f5f8
Publikováno v:
Seminars in Immunopathology
Activation and regulation of the cascade systems of the blood (the complement system, the coagulation/contact activation/kallikrein system, and the fibrinolytic system) occurs via activation of zymogen molecules to specific active proteolytic enzymes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d3bcb5f099cc7da8c44b8c2e998143c
Autor:
Miriam Kalbitz, Stephanie Denk, Sebastian Weckbach, Rebecca Wiegner, Manfred Weiss, Miriam D. Neher, David A. C. Messerer, Peter Radermacher, Markus Huber-Lang, Daniel Rittirsch, Kristina Nilsson-Ekdahl, Bo Nilsson, Josef Vogt, Anita Ignatius, John D. Lambris, Jörg Köhl, Florian Gebhard
Publikováno v:
The Journal of Immunology. 198:4846-4854
During sepsis, excessive activation of the complement system with generation of the anaphylatoxin C5a results in profound disturbances in crucial neutrophil functions. Moreover, because neutrophil activity is highly dependent on intracellular pH (pHi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8821c3ed42d93dd72d166b5da71b33e
https://doi.org/10.4049/jimmunol.1700393
https://doi.org/10.4049/jimmunol.1700393
Publikováno v:
Immunobiology. 221:1073-1079
The humoral serine proteases of the complement system and the coagulation system play central roles during the events of an inflammatory response. While the complement system confers immunoprotective and -regulatory functions, the coagulation cascade
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d19bfa3edb46108948b04ac2794abc80
https://doi.org/10.1016/j.imbio.2016.06.005
https://doi.org/10.1016/j.imbio.2016.06.005
Autor:
Rebecca Wiegner, Anita Ignatius, Peter Radermacher, Anna Kovtun, Markus Huber-Lang, Stephanie Bergdolt
Publikováno v:
European Cells & Materials, Vol 32, Pp 152-162 (2016)
Europe PubMed Central
Europe PubMed Central
Delayed bone fracture healing and the formation of non-unions represent an important clinical problem, particularly in polytrauma patients who suffer from posttraumatic systemic inflammation. However, the underlying pathomechanisms remain unclear. Ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbd619d1ca4bc1be42cb82945ed9df07
http://www.ecmjournal.org/papers/vol032/pdf/v032a10.pdf
http://www.ecmjournal.org/papers/vol032/pdf/v032a10.pdf
Autor:
Christian Ehrnthaller, Miriam Kalbitz, Rebecca Wiegner, Oscar McCook, Stephanie Denk, Sebastian Weckbach, Felix Hönes, David A. C. Messerer, Markus Huber-Lang, Manfred Weiss, Sonja Braumüller, Peter Radermacher, Florian Gebhard
Publikováno v:
Mediators of Inflammation
Mediators of Inflammation, Vol 2015 (2015)
Mediators of Inflammation, Vol 2015 (2015)
Severe tissue trauma-induced systemic inflammation is often accompanied by evident or occult blood-organ barrier dysfunctions, frequently leading to multiple organ dysfunction. However, it is unknown whether specific barrier molecules are shed into t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c35be8f2360ea92fcc54f1bf28411b2
https://doi.org/10.1155/2015/463950
https://doi.org/10.1155/2015/463950
Autor:
Miriam Kalbitz, Tim Eiseler, Florian Gebhard, David A. C. Messerer, Holger Barth, Rebecca Wiegner, Stephanie Denk, Manfred Weiss, John D. Lambris, Stephan Paschke, Ronald P. Taylor, Eberhard Barth, Markus Huber-Lang, Tobias Martin, Katharina Pfeiffer, Erika M. Cook, Margaret A. Lindorfer
The complement and neutrophil defence systems, as major components of innate immunity, are activated during inflammation and infection. For neutrophil migration to the inflamed region, we hypothesized that the complement activation product C5a induce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbc97bddaa20246781c22d632270e241
https://europepmc.org/articles/PMC5773343/
https://europepmc.org/articles/PMC5773343/
Autor:
Florian Gebhard, Philipp Kellermann, Stephanie Denk, Christian Karl Braun, Peter Radermacher, Philipp Eisele, Julia J. Ohmann, Felix M. Hoenes, Lisa Wrba, Annette Palmer, Sebastian Weckbach, Anke Schultze, Rebecca Wiegner, Sebastian Hafner, Markus Huber-Lang, Sonja Braumüller, Ulrich Wachter, Oscar McCook
Publikováno v:
Shock (Augusta, Ga.). 49(2)
Hemorrhagic shock (HS) after tissue trauma increases the complication and mortality rate of polytrauma (PT) patients. Although several murine trauma models have been introduced, there is a lack of knowledge about the exact impact of an additional HS.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::242d2b4a6499015717b276d2bc459bba
https://pubmed.ncbi.nlm.nih.gov/28614141
https://pubmed.ncbi.nlm.nih.gov/28614141
Autor:
N.-E. Rudhart, E. Barth, Markus Huber-Lang, Rolf E. Brenner, Lorenz Lampl, Rebecca Wiegner, Florian Gebhard
Publikováno v:
European journal of trauma and emergency surgery : official publication of the European Trauma Society. 44(4)
Mesenchymal stem cells (MSCs) are primarily stromal cells present in bone marrow and other tissues that are crucial for tissue regeneration and can be mobilized into peripheral blood after different types of organ damage. However, little is known abo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3940c7bf601fb327b4fdb1f36b1e307
https://pubmed.ncbi.nlm.nih.gov/28986662
https://pubmed.ncbi.nlm.nih.gov/28986662