Zobrazeno 1 - 4 of 4 pro vyhledávání: '"Rebecca Warmers"'
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Abstract 4905: Anticancer activity and paraptosis induction of novel bipyridine-silver(I) compounds against resistant colorectal and ovarian cancer cell lines
Autor: Alessia Stefanelli, Ricardo G. Teixeira, Adhan Pilon, Rebecca Warmers, Ingo Ott, Christian R. Kowol, Anamaria Brozovic, Ana Isabel Tomaz, Andreia Valente, Petra Heffeter
Publikováno v: Cancer Research. 83:4905-4905
Background: Platinum-based anticancer drugs (e.g. Carboplatin and Oxaliplatin) are frequently applied in chemotherapy regimens against several types of cancer including ovarian carcinoma (OC) and colorectal carcinoma (CRC). However, intrinsic or acqu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b01e23dcef8595c1c775d02128e54286
https://doi.org/10.1158/1538-7445.am2023-4905
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2
PARP1 and XRCC1 exhibit a reciprocal relationship in genotoxic stress response
Autor: Julia M. Reber, Jovana Božić-Petković, Michelle Lippmann, Marvin Mazzardo, Asisa Dilger, Rebecca Warmers, Alexander Bürkle, Aswin Mangerich
Publikováno v: Cell biology and toxicologyReferences.
AbstractPARP1 (aka ARTD1) acts as a prime sensor of cellular genotoxic stress response. PARP1 detects DNA strand breaks and subsequently catalyzes the formation of poly(ADP-ribose) (PAR), which leads to the recruitment of the scaffold protein XRCC1 d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dccbd0a89d2e822ed5eeb78ce12778c
https://pubmed.ncbi.nlm.nih.gov/35778544
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