Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Rebecca W. Y. Chan"'
Autor:
Tingting Xie, Guangya Wang, Spencer C. Ding, Wing-Shan Lee, Suk Hang Cheng, Rebecca W. Y. Chan, Ze Zhou, Mary-Jane L. Ma, Diana S. C. Han, Jeremy Y. C. Teoh, W. K. Jacky Lam, Peiyong Jiang, Rossa W. K. Chiu, K. C. Allen Chan, Y. M. Dennis Lo
Publikováno v:
npj Genomic Medicine, Vol 7, Iss 1, Pp 1-8 (2022)
Abstract Single-stranded ends of double-stranded DNA (jagged ends) are more abundant in urinary DNA than in plasma DNA. However, the lengths of jagged ends in urinary DNA remained undetermined, as a previous method used for urinary DNA jagged end seq
Externí odkaz:
https://doaj.org/article/e4eb0c32fae44646b1cdb1df9e10c7f5
Autor:
Meihui Chen, Rebecca W Y Chan, Peter P H Cheung, Meng Ni, Danny K L Wong, Ze Zhou, Mary-Jane L Ma, Liangbo Huang, Xinzhou Xu, Wing-Shan Lee, Guangya Wang, Kathy O Lui, W K Jacky Lam, Jeremy Y C Teoh, Chi-Fai Ng, Peiyong Jiang, K C Allen Chan, Rossa W K Chiu, Y M Dennis Lo
Publikováno v:
PLoS Genetics, Vol 18, Iss 7, p e1010262 (2022)
Urinary cell-free DNA (ucfDNA) is a potential biomarker for bladder cancer detection. However, the biological characteristics of ucfDNA are not well understood. We explored the roles of deoxyribonuclease 1 (DNASE1) and deoxyribonuclease 1-like 3 (DNA
Externí odkaz:
https://doaj.org/article/d9987df5b47d4a6084458cedce82ae43
Autor:
Guangya Wang, W K Jacky Lam, Lowell Ling, Mary-Jane L Ma, Saravanan Ramakrishnan, Don C T Chan, Wing-Shan Lee, Suk Hang Cheng, Rebecca W Y Chan, Stephanie C Y Yu, Irene O L Tse, Wai Tat Wong, Peiyong Jiang, Rossa W K Chiu, K C Allen Chan, Y M Dennis Lo
Publikováno v:
Clinical Chemistry. 69:189-201
Background Nuclear-derived cell-free DNA (cfDNA) molecules in blood plasma are nonrandomly fragmented, bearing a wealth of information related to tissues of origin. DNASE1L3 (deoxyribonuclease 1 like 3) is an important player in shaping the fragmenta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ca71723b6e355068e4756551eabf03c
https://doi.org/10.1093/clinchem/hvac197
https://doi.org/10.1093/clinchem/hvac197
Autor:
Ze Zhou, Mary-Jane L. Ma, Rebecca W. Y. Chan, W. K. Jacky Lam, Wenlei Peng, Wanxia Gai, Xi Hu, Spencer C. Ding, Lu Ji, Qing Zhou, Peter P. H. Cheung, Stephanie C. Y. Yu, Jeremy Y. C. Teoh, Cheuk-Chun Szeto, John Wong, Vincent W. S. Wong, Grace L. H. Wong, Stephen L. Chan, Edwin P. Hui, Brigette B. Y. Ma, Anthony T. C. Chan, Rossa W. K. Chiu, K. C. Allen Chan, Y. M. Dennis Lo, Peiyong Jiang
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Cell-free DNA (cfDNA) fragmentation is nonrandom, at least partially mediated by various DNA nucleases, forming characteristic cfDNA end motifs. However, there is a paucity of tools for deciphering the relative contributions of cfDNA cleavage pattern
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebd9260fa464576f47f0fd91e97cfc65
https://doi.org/10.1073/pnas.2220982120
https://doi.org/10.1073/pnas.2220982120
Autor:
Spencer C Ding, Rebecca W Y Chan, Wenlei Peng, Liangbo Huang, Ze Zhou, Xi Hu, Stefano Volpi, Linda T Hiraki, Augusto Vaglio, Paride Fenaroli, Paola Bocca, Lai Shan Tam, Priscilla C H Wong, Lydia H P Tam, Peiyong Jiang, Rossa W K Chiu, K C Allen Chan, Y M Dennis Lo
Publikováno v:
Clinical Chemistry. 68:917-926
Background Jagged ends of plasma DNA are a recently recognized class of fragmentomic markers for cell-free DNA, reflecting the activity of nucleases. A number of recent studies have also highlighted the importance of jagged ends in the context of pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbffd12aa5fa85a4092c576d832f5156
https://doi.org/10.1093/clinchem/hvac050
https://doi.org/10.1093/clinchem/hvac050
Autor:
Qing Zhou, Guannan Kang, Peiyong Jiang, Rong Qiao, W. K. Jacky Lam, Stephanie C. Y. Yu, Mary-Jane L. Ma, Lu Ji, Suk Hang Cheng, Wanxia Gai, Wenlei Peng, Huimin Shang, Rebecca W. Y. Chan, Stephen L. Chan, Grace L. H. Wong, Linda T. Hiraki, Stefano Volpi, Vincent W. S. Wong, John Wong, Rossa W. K. Chiu, K. C. Allen Chan, Y. M. Dennis Lo
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Cell-free DNA (cfDNA) fragmentation patterns contain important molecular information linked to tissues of origin. We explored the possibility of using fragmentation patterns to predict cytosine-phosphate-guanine (CpG) methylation of cfDNA, obviating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b97634f42ad78364b56a157180672c8
https://doi.org/10.1073/pnas.2209852119
https://doi.org/10.1073/pnas.2209852119
Autor:
Tingting Xie, Guangya Wang, Spencer C. Ding, Wing-Shan Lee, Suk Hang Cheng, Rebecca W. Y. Chan, Ze Zhou, Mary-Jane L. Ma, Diana S. C. Han, Jeremy Y. C. Teoh, W. K. Jacky Lam, Peiyong Jiang, Rossa W. K. Chiu, K. C. Allen Chan, Y. M. Dennis Lo
Publikováno v:
NPJ genomic medicine. 7(1)
Single-stranded ends of double-stranded DNA (jagged ends) are more abundant in urinary DNA than in plasma DNA. However, the lengths of jagged ends in urinary DNA remained undetermined, as a previous method used for urinary DNA jagged end sequencing a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::173c17d1a4b9367e0f3007a8a0d4a3f8
https://pubmed.ncbi.nlm.nih.gov/35197474
https://pubmed.ncbi.nlm.nih.gov/35197474
Autor:
Shirley S.M. Fong, Shamay S.M. Ng, Ying-Ki Fung, Charles W. K. Lai, Mandy M L Chung, Rebecca W Y Chan, Stefanie S.L. Lam
Publikováno v:
Journal of rehabilitation medicine. 46(10)
Objective (i) To investigate the intra-rater, inter-rater and test-retest reliability and minimal detectable change of the Alternate Step Test (AST) when assessing people with chronic stroke. (ii) To quantify the correlation between AST times and str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b829059c6e87e8105fb2c529a5384b4
https://pubmed.ncbi.nlm.nih.gov/25167536
https://pubmed.ncbi.nlm.nih.gov/25167536