Zobrazeno 1 - 10 of 10 pro vyhledávání: '"Rebecca Savioz"'
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Toxicological Assessment In Vitro
Autor: Carole Mathis, Marco van der Toorn, Julia Hoeng, Damian McHugh, Patrick Vanscheeuwijck, Manuel C. Peitsch, Anita R. Iskandar, Filippo Zanetti, Rebecca Savioz, Carine Poussin, Walter K. Schlage, Daniel J. Smart, David Bovard
Publikováno v: Toxicological Evaluation of Electronic Nicotine Delivery Products ISBN: 9780128204900
Electronic nicotine delivery products (ENDPs) emit lower levels of toxicants than cigarettes, and, consequently, ENPD aerosols have the potential to be less toxic than cigarette smoke (CS). Toxicological assessment of ENDPs relies heavily on in vitro
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b8dbe829d095276ff0d4c5450df2e0d1
https://doi.org/10.1016/b978-0-12-820490-0.00018-3
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4
Evaluation of the safety profile of an electronic vapour product used for two years by smokers in a real-life setting
Autor: Claire Martin, Jim Bush, Rebecca Savioz, Grant O'Connell, Annelize Koch, Tanvir Walele
Publikováno v: Regulatory Toxicology and Pharmacology. 92:226-238
The safety profile of Puritane™, a closed system electronic vapour product (EVP), was evaluated when used by smokers of conventional cigarettes (CCs) for 24 months in a real-life setting. The study was a two-centre ambulatory clinical study with 20
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3866c33d0c8e1efda41428b02fd47eee
https://doi.org/10.1016/j.yrtph.2017.12.010
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A randomised, parallel group study to evaluate the safety profile of an electronic vapour product over 12 weeks
Autor: Simon Craige, Tanvir Walele, Ana S. Cravo, Girish Sharma, Claire Martin, Jim Bush, Rebecca Savioz
Publikováno v: Regulatory Toxicology and Pharmacology. 81:S1-S14
A randomised, parallel group clinical study was performed to evaluate the safety profile of an e-vapour product (EVP; 2.0% nicotine) in smokers of conventional cigarettes (CCs) switching to use the EVP for 12 weeks. During the study, no clinically si
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a33b3fb047370fbcd13a533f6dc06d1
https://doi.org/10.1016/j.yrtph.2016.10.003
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7
A randomised, crossover study on an electronic vapour product, a nicotine inhalator and a conventional cigarette. Part A: Pharmacokinetics
Autor: Josie Williams, Claire Martin, Rebecca Savioz, Girish Sharma, Tanvir Walele
Publikováno v: Regulatory Toxicology and Pharmacology. 74:187-192
The pharmacokinetic (PK) profile of nicotine delivered by an Electronic Vapour Product (EVP) was characterised in a 2-part study in smokers. The study was designed as a randomised, controlled, four-way crossover trial. Part 1 compared an unflavoured
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cc4e9268fe7c3de98cebd232d3179a8
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8
A randomised, crossover study on an electronic vapour product, a nicotine inhalator and a conventional cigarette. Part B: Safety and subjective effects
Autor: Tanvir Walele, Rebecca Savioz, Claire Martin, Josie Williams, Girish Sharma
Publikováno v: Regulatory Toxicology and Pharmacology. 74:193-199
An Electronic Vapour Product (EVP) has been evaluated for short-term safety parameters and subjective effects in a 2-part study, in smokers. Part 1 compared the EVP with unflavoured (UF) and flavoured (FL) e-liquid at 2.0% nicotine to a conventional
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fc0fbefc72892623dcebd9db207387b
https://doi.org/10.1016/j.yrtph.2015.12.004
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9
Determination of Selected Chemical Levels in Room Air and on Surfaces after the Use of Cartridge- and Tank-Based E-Vapor Products or Conventional Cigarettes
Autor: Qiwei Liang, I. Gene Gillman, Jianmin Liu, Mohamadi Sarkar, Piyush Patel, Rebecca Savioz, Ali A. Rostami, Michael J. Oldham, Karl A. Wagner
Publikováno v: International Journal of Environmental Research and Public Health, Vol 14, Iss 9, p 969 (2017)
International Journal of Environmental Research and Public Health; Volume 14; Issue 9; Pages: 969
International Journal of Environmental Research and Public Health
There is an ongoing debate regarding the potential of secondhand exposure of non-users to various chemicals from use of e-vapor products (EVPs). Room air levels of 34 chemicals (nicotine, propylene glycol (PG), glycerol, 15 carbonyl chemicals, 12 vol
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::432cf68dc36cac1e6672090fd2ba22ee
https://www.mdpi.com/1660-4601/14/9/969
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10
GLUT8 Is Dispensable for Embryonic Development but Influences Hippocampal Neurogenesis and Heart Function
Autor: Thierry Pedrazzini, Friedrich Beermann, Bernard Thorens, Mathieu Membrez, Jacques-Antoine Haefliger, Edith Hummler, Rebecca Savioz
Publikováno v: Molecular and Cellular Biology. 26:4268-4276
GLUT8 is a glucose transporter isoform expressed at high levels in testis; at intermediate levels in the brain, including the hippocampus; and at lower levels in the heart and several other tissues. GLUT8 is located in an intracellular compartment an
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77b375d08e37a126fce7eea34ddec686
https://doi.org/10.1128/mcb.00081-06
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