Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Rebecca Salmonsen"'
Autor:
Rebecca Salmonsen, Catherine McQuain, Sumner Burstein, Guigen Li, Padmanabha V. Kattamuri, Hao Sun
Publikováno v:
Life Sciences. 92:506-511
To design and synthesize novel N-(1-phenyl-2,3-dihydroxypropyl)arachidonylamides and evaluate their analgesic and anti-inflammatory potential.The murine macrophage cell line RAW 264.7 has been widely used as a model for inflammatory responses in vitr
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 22:872-875
Several N-linked amino acid-linoleic acid conjugates were studied for their potential as anti inflammatory agents. The parent molecule, N-linoleoylglycine was tested in an in vivo model, the mouse peritonitis assay where it showed activity in reducin
Publikováno v:
Journal of Cellular Biochemistry. 112:3227-3233
N-arachidonoylglycine (NAgly) is an endogenous signaling lipid that is a member of the eicosanoid super family and is related to anandamide. It shows anti-inflammatory activity in vivo in the mouse peritonitis model where it reduces migration of infl
Autor:
Rebecca Salmonsen, Sumner Burstein
Publikováno v:
Bioorganic & Medicinal Chemistry. 16:9644-9651
A series of amide derivatives of long-chain fatty acids has been studied for their effects on the proliferation of cancer cells in vitro. Fatty acids ranged from palmitic to higher polyunsaturated types containing 22 carbon atoms. The amino portions
Autor:
Stephen N. Jones, Hoi Pang Low, Rebecca Salmonsen, Béatrice Gréco, Lawrence D. Recht, Judith Gallant, Alonzo H. Ross, Eric C. Johnson
Publikováno v:
STEM CELLS. 22:600-608
Earlier studies reported that neural stem (NS) cells injected into blastocysts appeared to be pluripotent, differentiating into cells of all three germ layers. In this study, we followed in vitro green fluorescent protein (GFP)-labeled NS and embryon
Autor:
Rebecca Salmonsen, Tod K. Turner, Stephen N. Jones, Lawrence Recht, Alonzo H. Ross, Li Li, Pier Paolo Pandolfi, Antonio Di Cristofano, Fenghua Liu, N. Scott Litofsky
Publikováno v:
Molecular and Cellular Neuroscience. 20:21-29
PTEN is a lipid phosphatase, and PTEN mutations are associated with gliomas, macrocephaly, and mental deficiencies. We have used PTEN +/− mice to assess PTEN's role in subventricular zone (SVZ) precursor cells. For cultured SVZ neurosphere cells, h
Autor:
Taichang Jang, Rebecca Salmonsen, Mahesh B. Lachyankar, R R Nabi, T Kubiatowski, Lawrence D. Recht, N S Litofsky, Peter J. Quesenberry, Alonzo H. Ross
Publikováno v:
Journal of Neurosurgery. 95:480-488
Object. Glioblastoma multiforme is the most malignant of the primary brain tumors and aggressively infiltrates surrounding brain tissue, resulting in distant foci within the central nervous system, thereby rendering this tumor surgically incurable. T
Autor:
Robert B. Zurier, Pusha Karim, George Pipia, Sumner Burstein, Lawrence Recht, Alonzo H. Ross, N. Scott Litofsky, Ronald Rosetti, Tai Jang, Tomacz Kubiatowski, Rebecca Salmonsen
Publikováno v:
Biochemical Pharmacology. 62:755-763
One of the endogenous transformation products of tetrahydrocannabinol (THC) is THC-11-oic acid, and ajulemic acid (AJA; dimethylheptyl-THC-11-oic acid) is a side-chain synthetic analog of THC-11-oic acid. In preclinical studies, AJA has been found to
Publikováno v:
Cancer Immunology, Immunotherapy. 42:357-361
Previous studies have shown that immunotoxin action is dependent upon selective binding to the target cell, internalization and then passage into the cytosol. It is important to define precisely how these critical steps are controlled so that the und
Autor:
Edward O'Connell, James E Evans, Hua Gao, Yingwang Liu, Sumner Burstein, Rebecca Salmonsen, Julie Lamusta, Weifang Zhang, Jason J. Chen
Publikováno v:
North American journal of medicinescience. 4(2)
The plant Brucea javanica has shown impressive efficacy for treating various diseases including cancer. However, the mechanism by which B. javanica acts is poorly understood. We have established tissue culture assays to study the effects of B. javani