Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Rebecca Salazar"'
Autor:
Aleix Ribas-Latre, Anja Karlstaedt, Heidi Vitrac, William P. Dillon, Deborah Vela, Hernan G. Vasquez, Gina De La Guardia, Heinrich Taegtmeyer, Corrine Baumgartner, Giovannis E Davogustto, Patrick H. Guthrie, Rebecca Salazar, Joseph R Martin, Kristin Eckel-Mahan
Publikováno v:
J Mol Cell Cardiol
Rationale The nutrient sensing mechanistic target of rapamycin complex 1 (mTORC1) and its primary inhibitor, tuberin (TSC2), are cues for the development of cardiac hypertrophy. The phenotype of mTORC1 induced hypertrophy is unknown. Objective To exa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a3ee7dfaf6d8d8460c33c0d25601e0b
https://doi.org/10.1016/j.yjmcc.2021.05.016
https://doi.org/10.1016/j.yjmcc.2021.05.016
Autor:
Walter Schiffer, David J. R. Taylor, Daniel Soetkamp, Benjamin D. Gould, Jennifer E. Van Eyk, Anna Guzman, Weston R. Spivia, Lin Tan, Heinrich Taegtmeyer, Helen B. Burks, Blake Hanson, Anja Karlstaedt, Heidi Vitrac, Philip L. Lorenzi, Rebecca Salazar, Daniel McNavish, An Q Dinh, Roberta A. Gottlieb, Koen Raedschelders, Stavros Azinas
About 20-30% of cancer-associated deaths are due to complications from cachexia which is characterized by skeletal muscle atrophy. Metabolic reprogramming in cancer cells causes body-wide metabolic and proteomic remodeling, which remain poorly unders
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0de41df7869a7873d19bfadcb5e41a9c
https://doi.org/10.1101/2020.10.13.338202
https://doi.org/10.1101/2020.10.13.338202
Autor:
Heidi Vitrac, Anja Karlstaedt, Rebecca Salazar, Heinrich Taegtmeyer, Ralph J. DeBerardinis, Benjamin D. Gould, Brandon Faubert
Publikováno v:
Circulation Research. 127
Cancer cells rewire metabolism to support tumor growth and proliferation. In isocitrate dehydrogenase (IDH) 1 and 2 mutant tumors, increased plasma levels of the oncometabolite D-2-hydroxyglutarate (D2-HG) are associated with systemic effects, includ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e6c71e8885ebe7cf6a055552732ac45
https://doi.org/10.1161/res.127.suppl_1.308
https://doi.org/10.1161/res.127.suppl_1.308
Autor:
Rebecca Salazar
Publikováno v:
Shakespeare Bulletin. 36:449-466
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b659e99a9436aab0ca11a75f22bc162
https://doi.org/10.1353/shb.2018.0040
https://doi.org/10.1353/shb.2018.0040
Autor:
Rebecca Salazar
Ce recueil engagé de Rebecca Salazar nous transporte tantôt à Sudbury, ville où l'autrice a grandi, tantôt dans la région de Fredericton, son lieu d'accueil, tantôt encore chez ses aïeux en Colombie. Des réflexions percutantes surgissent au
Autor:
Roberta A. Gottlieb, Helen B. Burks, Anja Karlstaedt, Rebecca Salazar, Jennifer VanEyk, David J. Taylor, An Dinh, Benjamin D. Gould, Daniel Soetkamp, Walter Schiffer, Blake Hanson, Heinrich Taegtmeyer, Weston R. Spivia, Daniel McNavish, Koen Raedschelders, Heidi Vitrac
Publikováno v:
Circulation Research. 125
Metabolic rewiring is a hallmark of cancer and muscle cells. In isocitrate dehydrogenase 1 and 2 mutant tumors, increased plasma levels of the oncometabolite D-2-hydroxyglutarate (D2-HG) are associated with systemic effects, including myopathy. Our r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48e590eb88f724176a5a658c1fe101f6
https://doi.org/10.1161/res.125.suppl_1.361
https://doi.org/10.1161/res.125.suppl_1.361
Autor:
Giovanni Davogustto, Hernan Vasquez, Heinrich Taegtmeyer, Rebecca Salazar, Patrick H. Guthrie
Publikováno v:
Journal of the American College of Cardiology. 71:A931
When stressed, the heart remodels metabolically and structurally. Metabolically, increases its reliance on carbohydrates for energy provision. Structurally, it hypertrophies. A common pathway for both of these changes is the activation of the mechani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b40d86a4c3ccc1ce7da48565ce29bc6
https://doi.org/10.1016/s0735-1097(18)31472-4
https://doi.org/10.1016/s0735-1097(18)31472-4
Publikováno v:
Journal of the American College of Cardiology. 71:A802
The Warburg effect in cancer cells entails enhanced lactate production from glucose in the presence of oxygen. We have recently discovered footprints of the Warburg effect in the failing human heart and that metabolic remodeling precedes structural r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68679f7339410c9d4ba1365e928dace5
https://doi.org/10.1016/s0735-1097(18)31343-3
https://doi.org/10.1016/s0735-1097(18)31343-3
Publikováno v:
Circulation Research. 117
The heart remodels metabolically and structurally before it fails. Metabolically, the heart increases its reliance on carbohydrates for energy provision. Structurally, the heart hypertrophies to sustain increased hemodynamic stress. There is evidence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d275ce4df005fd5c267ad30f63181b5e
https://doi.org/10.1161/res.117.suppl_1.102
https://doi.org/10.1161/res.117.suppl_1.102
Publikováno v:
Circulation Research. 111
The heart adapts to changes in load by remodeling both metabolically and structurally. During this process, cardiomyocytes break down unnecessary or damaged proteins and use the resulting amino acids for the synthesis of new proteins and/or energy pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc486b5ca404a3c90bb6da62f3c35e81
https://doi.org/10.1161/res.111.suppl_1.a294
https://doi.org/10.1161/res.111.suppl_1.a294