Výsledky vyhledávání - "Rebecca S. Vogel"

Regional distribution and behavioral correlates of 5-HT2A receptors in Alzheimer's disease with [18F]deuteroaltanserin and PET

Autor: Gilles Tamagnan, Ronald M. Baldwin, Lekshmi Santhosh, Kristina M. Estok, Christopher H. van Dyck, Effie M. Mitsis, Martha G. MacAvoy, Rebecca S. Vogel, Julie K. Staley

Publikováno v: Psychiatry Research: Neuroimaging. 173:212-217

Postmortem studies show reductions in brain serotonin 2A (5-HT(2A)) receptors in Alzheimer's disease (AD). Converging evidence also suggests that serotonergic dysregulation may contribute to behavioral symptoms that frequently occur in AD. This study

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fa33db53a299de9b9ddb951b56069a0
https://doi.org/10.1016/j.pscychresns.2009.03.007

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Radiosynthesis of 3-(3-[18F]fluoropropoxy)-4-(benzyloxy)-N-[(1-dimethylaminocyclopentyl)methyl]-5-methoxybenzamide, a potential PET radiotracer for the glycine transporter GlyT-2

Autor: Gilles Tamagnan, Ronald M. Baldwin, Rebecca S. Vogel, Louis Amici, Haibin Tian

Publikováno v: Journal of Labelled Compounds and Radiopharmaceuticals. 49:1247-1258

The recently described selective and potent GlyT2 antagonist, 4-benzyloxy-3,5-dimethoxy-N-[(1-dimethylaminocyclopentyl) methyl]benzamide (IC50=16 nM) provided an important additional tool to further characterize GlyT2 pharmacology. In order to identi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9741bf0183350cd8ac4c704484e48c27
https://doi.org/10.1002/jlcr.1145

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