Zobrazeno 1 - 10
of 350
pro vyhledávání: '"Rebecca S Heist"'
Autor:
Yen-Tsung Huang, Xihong Lin, Lucian R Chirieac, Ray McGovern, John C Wain, Rebecca S Heist, Vidar Skaug, Shanbeh Zienolddiny, Aage Haugen, Li Su, David C Christiani
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e22961 (2011)
Lung cancer, of which more than 80% is non-small cell, is the leading cause of cancer-related death in the United States. Copy number alterations (CNAs) in lung cancer have been shown to be positionally clustered in certain genomic regions. However,
Externí odkaz:
https://doaj.org/article/7e06ef35d7494f218bc0b238f5ff1056
Autor:
Ibiayi Dagogo-Jack, MD, Lesli A. Kiedrowski, MS, MPH, Rebecca S. Heist, MD, MPH, Jessica J. Lin, MD, Catherine B. Meador, MD, PhD, Elizabeth A. Krueger, NP, Andrew Do, BS, Jennifer Peterson, BS, Lecia V. Sequist, MD, MPH, Justin F. Gainor, MD, Jochen K. Lennerz, MD, PhD, Subba R. Digumarthy, MD
Publikováno v:
JTO Clinical and Research Reports, Vol 4, Iss 8, Pp 100534- (2023)
Introduction: MET amplification is a potentially actionable resistance mechanism in ALK-rearranged (ALK+) lung cancer. Studies describing treatment outcomes of this molecular subgroup are lacking. Methods: We assembled a cohort of patients with ALK+
Externí odkaz:
https://doaj.org/article/48f3d6a56b8d4f66bc9f438add97a0a8
Autor:
Alissa J. Cooper, MD, Alona Muzikansky, MA, Jochen Lennerz, MD, PhD, Farhaana Narinesingh, M.B.B.S., Mari Mino-Kenudson, MD, Yin P. Hung, MD, PhD, Zofia Piotrowska, MD, MHS, Ibiayi Dagogo-Jack, MD, Lecia V. Sequist, MD, MPH, Justin F. Gainor, MD, Jessica J. Lin, MD, Rebecca S. Heist, MD, MPH
Publikováno v:
JTO Clinical and Research Reports, Vol 3, Iss 9, Pp 100390- (2022)
Introduction: Co-occurring mutations in KRAS-mutant NSCLC are associated with discrete biological properties and modulate therapeutic susceptibilities. As G12D-specific inhibitors are expected to enter the clinic, we sought to investigate the charact
Externí odkaz:
https://doaj.org/article/b74d2bef942c4556b6ea5685e2ff735a
Autor:
A.J. Piper-Vallillo, MD, Julia K. Rotow, MD, Jacqueline V. Aredo, MD, Khvaramze Shaverdashvili, MD, PhD, Jia Luo, MD, Jennifer W. Carlisle, MD, Hatim Husain, MD, Alona Muzikansky, MA, Rebecca S. Heist, MD, Deepa Rangachari, MD, Suresh S. Ramalingam, MD, Heather A. Wakelee, MD, Helena A. Yu, MD, Lecia V. Sequist, MD, Joshua M. Bauml, MD, Joel W. Neal, MD, PhD, Zofia Piotrowska, MD, MHS
Publikováno v:
JTO Clinical and Research Reports, Vol 3, Iss 6, Pp 100328- (2022)
Introduction: This multicenter review evaluated the efficacy and safety of osimertinib dose escalation for central nervous system (CNS) progression developing on osimertinib 80 mg in EGFR-mutant NSCLC. Methods: Retrospective review identified 105 pat
Externí odkaz:
https://doaj.org/article/a0defd29b0c2448591b1a44036d37442
Autor:
Alissa J. Cooper, Rebecca S. Heist
Publikováno v:
Hematology/Oncology Clinics of North America. 37:623-658
Autor:
Jürgen Wolf, Edward B. Garon, Harry J.M. Groen, Daniel S.W. Tan, Isabelle Gilloteau, Sylvie Le Mouhaer, Marcio Hampe, Can Cai, Andrea Chassot-Agostinho, Maria Reynolds, Bintu Sherif, Rebecca S. Heist
Publikováno v:
European Journal of Cancer. 183:98-108
Introduction: Capmatinib, a MET inhibitor, showed substantial antitumour activity with manageable side effects in patients with MET exon 14 (METex14)-mutated advanced non-small cell lung cancer (aNSCLC) in the GEOMETRY mono-1 study. We report patient
Autor:
Pasi A. Jänne, Gregory J. Riely, Shirish M. Gadgeel, Rebecca S. Heist, Sai-Hong I. Ou, Jose M. Pacheco, Melissa L. Johnson, Joshua K. Sabari, Konstantinos Leventakos, Edwin Yau, Lyudmila Bazhenova, Marcelo V. Negrao, Nathan A. Pennell, Jun Zhang, Kenna Anderes, Hirak Der-Torossian, Thian Kheoh, Karen Velastegui, Xiaohong Yan, James G. Christensen, Richard C. Chao, Alexander I. Spira
Publikováno v:
New England Journal of Medicine. 387:120-131
Autor:
Marcelo V. Negrao, Haniel A. Araujo, Giuseppe Lamberti, Alissa J. Cooper, Neal S. Akhave, Teng Zhou, Lukas Delasos, J Kevin. Hicks, Mihaela Aldea, Gabriele Minuti, Jacobi Hines, Jacqueline V. Aredo, Michael J. Dennis, Turja Chakrabarti, Susan C. Scott, Paolo Bironzo, Matthias Scheffler, Petros Christopoulos, Albrecht Stenzinger, Jonathan W. Riess, So Yeon Kim, Sarah B. Goldberg, Mingjia Li, Qi Wang, Yun Qing, Ying Ni, Minh Truong Do, Richard Lee, Biagio Ricciuti, Joao Victor. Alessi, Jing Wang, Blerina Resuli, Lorenza Landi, Shu-Chi Tseng, Mizuki Nishino, Subba R. Digumarthy, Waree Rinsurongkawong, Vadeerat Rinsurongkawong, Ara A Vaporciyan, George R. Blumenschein, Jianjun Zhang, Dwight H. Owen, Collin M. Blakely, Giannis Mountzios, Catherine A. Shu, Christine M. Bestvina, Marina Chiara. Garassino, Kristen A. Marrone, Jhanelle E. Gray, Sandip Pravin. Patel, Amy L. Cummings, Heather A. Wakelee, Juergen Wolf, Giorgio Vittorio. Scagliotti, Federico Cappuzzo, Fabrice Barlesi, Pradnya D. Patil, Leylah Drusbosky, Don L. Gibbons, Funda Meric-Bernstam, J. Jack Lee, John V. Heymach, David S. Hong, Rebecca S. Heist, Mark M. Awad, Ferdinandos Skoulidis
Publikováno v:
Cancer Discovery.
Molecular modifiers of KRAS G12C inhibitor (KRAS G12Ci) efficacy in advanced KRAS G12C-mutant NSCLC are poorly defined. In a large unbiased clinico-genomic analysis of 424 NSCLC patients, we identified and validated co-alterations in KEAP1, SMARCA4 a
Autor:
Alice T. Shaw, Jeffrey A. Engelman, Mari Mino-Kenudson, A. John Iafrate, Cyril H. Benes, Lecia V. Sequist, Jochen Lennerz, Rebecca S. Heist, Dora Dias-Santagata, Gad Getz, Colleen Keyes, Colleen Channick, Subba Digumarthy, Ashok Muniappan, Long P. Le, Lauren L. Ritterhouse, Jennifer Logan, Tiffany Huynh, Elizabeth Lockerman, Richard H. DiCecca, Dana Lee, Melissa Parks, Emily Chin, Manrose Singh, Katherine Schultz, Shirish Gadgeel, Ibiayi Dagogo-Jack, Ryohei Katayama, Ignaty Leshchiner, Luc Friboulet, Satoshi Yoda, Leila Dardaei, Justin F. Gainor
Supplementary Table S1. ALK inhibitors in clinical development. Supplementary Table S2. Summary of clinical characteristics of ALK-positive patients undergoing biopsies at the time of ALK inhibitor resistance. Supplementary Table S3. Paired, post-cri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36f44b92d5a824882ff78594553ca374
https://doi.org/10.1158/2159-8290.22531515.v1
https://doi.org/10.1158/2159-8290.22531515.v1
Autor:
Alice T. Shaw, Aaron N. Hata, Ted W. Johnson, Jeffrey A. Engelman, Mari Mino-Kenudson, Jochen K. Lennerz, Cyril H. Benes, A. John Iafrate, Rebecca S. Heist, Daria Timonina, Krystina E. Kattermann, Amanda K. Riley, Lorin A. Ferris, Justin F. Gainor, Harper Hubbeling, Sergei Timofeevski, Ibiayi Dagogo-Jack, Kylie Prutisto-Chang, Leila Dardaei, Adam Langenbucher, Luc Friboulet, Benjamin J. Burke, Michael S. Lawrence, Jessica J. Lin, Satoshi Yoda
suppl tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::695e64cddb17425642cdd97e3a2d9049
https://doi.org/10.1158/2159-8290.22532569
https://doi.org/10.1158/2159-8290.22532569