Zobrazeno 1 - 10
of 196
pro vyhledávání: '"Rebecca S, Mason"'
Autor:
Artur Shariev, Spiro Menounos, Alistair J. Laos, Pooja Laxman, Donna Lai, Sheng Hua, Anna Zinger, Christopher R. McRae, Llewellyn S. Casbolt, Valery Combes, Greg Smith, Tzong-tyng Hung, Katie M. Dixon, Pall Thordarson, Rebecca S. Mason, Abhirup Das
Publikováno v:
Redox Biology, Vol 38, Iss , Pp 101790- (2021)
Superoxide dismutase (SOD) is known to be protective against oxidative stress-mediated skin dysfunction. Here we explore the potential therapeutic activities of RM191A, a novel SOD mimetic, on skin. RM191A is a water-soluble dimeric copper (Cu2+-Cu3+
Externí odkaz:
https://doaj.org/article/f6c1604312804f1782e9f4a7446131c5
Autor:
Xiaoying Liu, Liang Ke, Jacky Ho, Myriam Abboud, Elias Mpofu, Tara C Brennan-Speranza, Rebecca S Mason, Kaye E Brock
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0229642 (2020)
Chinese women are known to have both a high prevalence of metabolic syndrome (MetS) and vitamin D deficiency (serum 25-hydroxyvitamin D (25OHD) 55 years) Macanese, anthropometry, blood samples and validated questionnaires, including sleep duration an
Externí odkaz:
https://doaj.org/article/72a4261cd2b24bdda3aa97512fafd4c2
Autor:
Tara C. Brennan-Speranza, David Mor, Wenhan Chang, Zhiqiang Cheng, Arthur D. Conigrave, Mark S. Rybchyn, Rebecca S. Mason
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 12
International Journal of Molecular Sciences, Vol 22, Iss 6509, p 6509 (2021)
Volume 22
Issue 12
International Journal of Molecular Sciences, Vol 22, Iss 6509, p 6509 (2021)
We recently found that, in human osteoblasts, Homer1 complexes to Calcium-sensing receptor (CaSR) and mediates AKT initiation via mechanistic target of rapamycin complex (mTOR) complex 2 (mTORC2) leading to beneficial effects in osteoblasts including
Autor:
Chen Yang, Robert C. Tuckey, Furkan Akif Ince, Mark S. Rybchyn, Jeremy Zhuo Ru Han, Warusavithana Gunawardena Manori De Silva, Wannit Tongkao-on, Myriam Abboud, Bianca Y McCarthy, Katie M. Dixon, Andrew J. A. Holland, Rebecca S. Mason, Andrzej Slominski
Publikováno v:
JBMR Plus
JBMR Plus, Vol 5, Iss 12, Pp n/a-n/a (2021)
JBMR Plus, Vol 5, Iss 12, Pp n/a-n/a (2021)
The vitamin D hormone, 1,25dihydroxyvitamin D3 (1,25(OH)2D3), and related compounds derived from vitamin D3 or lumisterol as a result of metabolism via the enzyme CYP11A1, have been shown, when applied 24 hours before or immediately after UV irradiat
Autor:
Alexander Tacey, Elysia Neist, Tzu-Hsuan Yeh, Christian M. Girgis, Itamar Levinger, Rebecca S. Mason, Melissa S. Cameron, Mark S. Rybchyn, Shalinie King, Julia Mathers, Tara C. Brennan-Speranza, Dean Ross
Publikováno v:
Nutrients
Nutrients, Vol 13, Iss 1666, p 1666 (2021)
Nutrients; Volume 13; Issue 5; Pages: 1666
Nutrients, Vol 13, Iss 1666, p 1666 (2021)
Nutrients; Volume 13; Issue 5; Pages: 1666
Increased risks of skeletal fractures are common in patients with impaired glucose handling and type 2 diabetes mellitus (T2DM). The pathogenesis of skeletal fragility in these patients remains ill-defined as patients present with normal to high bone
Autor:
Arthur D. Conigrave, Thor C. Møller, Hans Bräuner-Osborne, Andrew N. Keller, Daniela Riccardi, Katie Leach, Donald T. Ward, Enikö Kállay, Fadil M. Hannan, Rebecca S. Mason, Tracy M. Josephs, Rajesh V. Thakker
Publikováno v:
Leach, K, Hannan, F M, Josephs, T M, Keller, A N, Møller, T C, Ward, D T, Kallay, E, Mason, R S, Thakker, R V, Riccardi, D, Conigrave, A D & Bräuner-Osborne, H 2020, ' International Union of Basic and Clinical Pharmacology. CVIII. Calcium-Sensing Receptor Nomenclature, Pharmacology, and Function ', Pharmacological Reviews, vol. 72, no. 3, pp. 558-604 . https://doi.org/10.1124/pr.119.018531
Pharmacological Reviews
Pharmacol Rev
Pharmacological Reviews
Pharmacol Rev
The calcium-sensing receptor (CaSR) is a class C G protein-coupled receptor that responds to multiple endogenous agonists and allosteric modulators, including divalent and trivalent cations, L-amino acids, γ-glutamyl peptides, polyamines, polycation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::172ef793c4bcbce0c405d4a538a416f0
https://ora.ox.ac.uk/objects/uuid:36ba0adf-bb2b-4474-a8fa-928bf788b385
https://ora.ox.ac.uk/objects/uuid:36ba0adf-bb2b-4474-a8fa-928bf788b385
Autor:
Zhiqiang Cheng, Rebecca S. Mason, Tara C. Brennan-Speranza, Mark S. Rybchyn, Arthur D. Conigrave, David Mor, Wenhan Chang
We recently found that in human osteoblasts Homer1 complexes to CaSR and mediates AKT initiation via mTORC2 leading to beneficial effects in osteoblasts including -catenin stabilization and mTORC1 activation (doi: 10.1074/jbc.RA118.006587). Herein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d9fa7fe79f4e5cc30408d519da8341e
https://doi.org/10.20944/preprints202101.0232.v1
https://doi.org/10.20944/preprints202101.0232.v1
Autor:
Artur Shariev, Nicole Painter, Vivienne E. Reeve, Nikolas K. Haass, Mark S. Rybchyn, Furkan A. Ince, Rebecca S. Mason, Katie M. Dixon
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 218:106059
Melanoma is the most dangerous form of skin cancer, with poor prognosis in advanced stages. Vitamin D, also produced by ultraviolet radiation, is known for its anti-proliferative properties in some cancers including melanoma. While vitamin D deficien
Autor:
Gary M. Halliday, Vivienne E. Reeve, Bianca Y McCarthy, Mark S. Rybchyn, Warusavithana Gunawardena Manori De Silva, Wannit Tongkao-on, Clare Gordon-Thomson, Chen Yang, Rebecca S. Mason, Katie M. Dixon
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 1962, p 1962 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 4
International Journal of Molecular Sciences
Volume 22
Issue 4
Susceptibility to photoimmune suppression and photocarcinogenesis is greater in male than in female humans and mice and is exacerbated in female estrogen receptor-beta knockout (ER-β-/-) mice. We previously reported that the active vitamin D hormone
Publikováno v:
Faculty Reviews
Severe vitamin D deficiency—25-hydroxyvitamin D (25OHD) concentrations below around 25–30 nmol/L—may lead to growth plate disorganization and mineralization abnormalities in children (rickets) and mineralization defects throughout the skeleton