Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Rebecca Rosser"'
Autor:
Owen M Wolkowitz, Synthia H Mellon, Elissa S Epel, Jue Lin, Firdaus S Dhabhar, Yali Su, Victor I Reus, Rebecca Rosser, Heather M Burke, Eve Kupferman, Mariana Compagnone, J Craig Nelson, Elizabeth H Blackburn
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17837 (2011)
Depression is associated with an unusually high rate of aging-related illnesses and early mortality. One aspect of "accelerated aging" in depression may be shortened leukocyte telomeres. When telomeres critically shorten, as often occurs with repeate
Externí odkaz:
https://doaj.org/article/0a688fa0a230445fb4327c5e33cc4443
Autor:
Owen M. Wolkowitz, Synthia H. Mellon, Yali Su, Victor I. Reus, Scott Mackin, Heather M. Burke, Rebecca Rosser, John Coetzee, Elissa S. Epel, Steven P. Hamilton, Craig J. Nelson, Laura Mahan, Michelle Coy, Michael W. Weiner, Susanne Mueller
Publikováno v:
European Journal of Psychotraumatology, Vol 3, Iss 0, Pp 1-1 (2012)
Oxidative stress (an imbalance between free radicals and the ability to neutralize them with antioxidants) occurs in several mental illnesses, including major depression (MDD). A major antioxidant in humans is glutathione peroxidase, which reduces GS
Externí odkaz:
https://doaj.org/article/adf8be62fc4d4b85b5f4476edfe9d6b5
Autor:
Owen M. Wolkowitz, Jodie Bryk, Synthia H. Mellon, Elissa S. Epel, Elizabeth H. Blackburn, Jue Lin, Robert H. Lustig, Peter J. Havel, Victor I. Reus, Heather M. Burke, Rebecca Rosser, John Coetzee, Laura Mahan, Michelle Coy, Steven P. Hamilton, Craig J. Nelson
Publikováno v:
European Journal of Psychotraumatology, Vol 3, Iss 0, Pp 1-1 (2012)
Obesity and the metabolic syndrome (MetS) predispose to multiple diseases and to accelerated cell aging as indexed by accelerated shortening of telomeres in peripheral blood mononuclear cells (PBMC's). Major depressive disorder (MDD) is often associa
Externí odkaz:
https://doaj.org/article/aba30d205eaa463489293ce56b290431
Autor:
Owen M. Wolkowitz, Jin Rowen, Sara Mason, Synthia H. Mellon, Victor I. Reus, Elissa S. Epel, Heather M. Burke, Rebecca Rosser, John Coetzee, Laura Mahan, Michelle Coy, J. Craig Nelson, Steven P. Hamilton, Sally Mendoza, Michael W. Weiner, Susanne Mueller
Publikováno v:
European Journal of Psychotraumatology, Vol 3, Iss 0, Pp 1-1 (2012)
Prior studies of Hypothalamic-Pituatary-Adrenal (HPA) associations with hippocampal (HC) volume have yielded inconsistent results. This might be due to the use of basal cortisol rather than cortisol reactivity measures and to the use of cortisol in i
Externí odkaz:
https://doaj.org/article/684277c1135e45ba9884d14c5c3a1560
Autor:
Owen M. Wolkowitz, Synthia H. Mellon, Elizabeth H. Blackburn, Jue Lin, Elissa S. Epel, Victor I. Reus, Heather M. Burke, Rebecca Rosser, John Coetzee, Laura Mahan, Michelle Coy, Scott Mackin, Steven P. Hamilton, J. Craig Nelson, Michael W. Weiner, Susanne Mueller
Publikováno v:
European Journal of Psychotraumatology, Vol 3, Iss 0, Pp 1-1 (2012)
The cellular enzyme elomerase replenishes telomeric DNA, which can be lost during repeated mitoses or during exposure to inflammation and oxidation. However, telomerase may have other, non-canonical functions, including (in animal models) antidepress
Externí odkaz:
https://doaj.org/article/a0951f45f542490e97182a96a006a4f4
Autor:
Brenda W.J.H. Penninx, Victor I. Reus, Synthia H. Mellon, Rebecca Rosser, Heather M. Burke, Elizabeth H. Blackburn, Owen M. Wolkowitz, Christina M. Hough, Brittany Fair, Laura Mahan, Elissa S. Epel, Jue Lin, Josine E. Verhoeven, Dóra Révész
Publikováno v:
Fair, B, Mellon, S H, Epel, E S, Lin, J, Révész, D, Verhoeven, J E, Penninx, B W, Reus, V I, Rosser, R, Hough, C M, Mahan, L, Burke, H M, Blackburn, E H & Wolkowitz, O M 2017, ' Telomere length is inversely correlated with urinary stress hormone levels in healthy controls but not in un-medicated depressed individuals-preliminary findings ', Journal of Psychosomatic Research, vol. 99, pp. 177-180 . https://doi.org/10.1016/j.jpsychores.2017.06.009
Journal of Psychosomatic Research, 99, 177-180. Elsevier Inc.
Journal of Psychosomatic Research, 99, 177-180. Elsevier Inc.
Objective Leukocyte telomere length (LTL) is a biomarker of cellular aging affected by chronic stress. The relationship of LTL to the stress hormones, cortisol and catecholamines, is unclear, as are possible differences between healthy controls (HC)
Autor:
F. Saverio Bersani, S. Jill James, Rebecca Rosser, Elissa S. Epel, Daniel Lindqvist, Firdaus S. Dhabhar, Josine E. Verhoeven, Synthia H. Mellon, Christina M. Hough, Owen M. Wolkowitz, Laura Mahan, Felipe A. Jain, Victor I. Reus
Publikováno v:
Psychoneuroendocrinology, 76, 197-205. Elsevier Limited
Lindqvist, D, Dhabhar, F S, James, S J, Hough, C M, Jain, F A, Bersani, F S, Reus, V I, Verhoeven, J E, Epel, E S, Mahan, L, Rosser, R, Wolkowitz, O M & Mellon, S H 2017, ' Oxidative stress, inflammation and treatment response in major depression ', Psychoneuroendocrinology, vol. 76, pp. 197-205 . https://doi.org/10.1016/j.psyneuen.2016.11.031
Lindqvist, D, Dhabhar, F S, James, S J, Hough, C M, Jain, F A, Bersani, F S, Reus, V I, Verhoeven, J E, Epel, E S, Mahan, L, Rosser, R, Wolkowitz, O M & Mellon, S H 2017, ' Oxidative stress, inflammation and treatment response in major depression ', Psychoneuroendocrinology, vol. 76, pp. 197-205 . https://doi.org/10.1016/j.psyneuen.2016.11.031
Objective Increased inflammation and oxidative stress have been shown in Major Depressive Disorder (MDD), although there is significant heterogeneity across studies. Whether markers of inflammation and oxidative stress are associated with antidepress
Autor:
Daniel Lindqvist, Elissa S. Epel, Synthia H. Mellon, F. Saverio Bersani, J. Craig Nelson, John Coetzee, Christina M. Hough, Rebecca Rosser, Heather M. Burke, Laura Mahan, Jue Lin, Victor I. Reus, Elizabeth H. Blackburn, Owen M. Wolkowitz
Publikováno v:
Molecular neuropsychiatry, vol 2, iss 2
Short leukocyte telomere length (LTL) may be associated with several psychiatric disorders, including major depressive disorder (MDD). Short LTL has previously been associated with poor response to psychiatric medications in bipolar disorder and schi
Autor:
Dóra Révész, Elissa S. Epel, Victor I. Reus, Daniel Lindqvist, Jue Lin, Synthia H. Mellon, Brenda W.J.H. Penninx, Josine E. Verhoeven, Owen M. Wolkowitz, F. Saverio Bersani, Laura Mahan, Rebecca Rosser, Christina M. Hough, Elizabeth H. Blackburn
Publikováno v:
Neuroscience and Biobehavioral Reviews, 55, 333-364. Elsevier Limited
Lindqvist, D, Epel, E S, Mellon, S H, Penninx, B W, Revesz, D, Verhoeven, J E, Reus, V I, Lin, J, Mahan, L, Hough, C M, Rosser, R, Bersani, F S, Blackburn, E H & Wolkowitz, O M 2015, ' Psychiatric disorders and leukocyte telomere length: Underlying mechanisms linking mental illness with cellular aging ', Neuroscience and Biobehavioral Reviews, vol. 55, pp. 333-364 . https://doi.org/10.1016/j.neubiorev.2015.05.007
Lindqvist, D, Epel, E S, Mellon, S H, Penninx, B W, Revesz, D, Verhoeven, J E, Reus, V I, Lin, J, Mahan, L, Hough, C M, Rosser, R, Bersani, F S, Blackburn, E H & Wolkowitz, O M 2015, ' Psychiatric disorders and leukocyte telomere length: Underlying mechanisms linking mental illness with cellular aging ', Neuroscience and Biobehavioral Reviews, vol. 55, pp. 333-364 . https://doi.org/10.1016/j.neubiorev.2015.05.007
Many psychiatric illnesses are associated with early mortality and with an increased risk of developing physical diseases that are more typically seen in the elderly. Moreover, certain psychiatric illnesses may be associated with accelerated cellular
Autor:
Elissa S. Epel, Owen M. Wolkowitz, Yali Su, Rebecca Rosser, Victor I. Reus, Daniel Lindqvist, Tony T. Yang, Susanne G. Mueller, R. Scott Mackin, Synthia H. Mellon, Laura Mahan
Publikováno v:
Psychiatry Research: Neuroimaging. 224:168-174
Several psychiatric disorders, including major depressive disorder (MDD), are associated with increased blood markers of oxidative stress. The relevance of this to the oxidation-sensitive hippocampus (HC) is unknown. We investigated the relationship