Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Rebecca R. Miles"'
Publikováno v:
BioTechniques, Vol 28, Iss 3, Pp 506-510 (2000)
Luciferase reporter vectors are commonly used for the functional analysis of basal promoter and enhancer elements of eukaryotic genes. Randomly occurring cisacting elements in the vector sequences that can spuriously respond to various transcription
Externí odkaz:
https://doaj.org/article/acc69be2483a415b8bc7b914ff488361
Autor:
Kirsten Deprey, Nefeli Batistatou, Marjoke F. Debets, Jack Godfrey, Kirstin B. VanderWall, Rebecca R. Miles, Livia Shehaj, Jiaxing Guo, Amy Andreucci, Pachamuthu Kandasamy, Genliang Lu, Mamoru Shimizu, Chandra Vargeese, Joshua A. Kritzer
Publikováno v:
ACS Chem Biol
A major obstacle to the development of effective oligonucleotide therapeutics is a lack of understanding about their cytosolic and nuclear penetration. To address this problem, we have applied the chloroalkane penetration assay (CAPA) to oligonucleot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ca7a1a52699e0b7e5fa1b2efc41faf6
https://europepmc.org/articles/PMC9252293/
https://europepmc.org/articles/PMC9252293/
Autor:
Joseph T. Brozinick, Steve Bauer, Evan M Niemeier, Thais de Castro Barbosa, Alexander V. Chibalin, Jorge Alsina-Fernandez, Julie Massart, Håkan K. R. Karlsson, Tamer Coskun, Lili Guo, Elizabeth O'Farrell, Juleen R. Zierath, Andrew Ryan, Milena Schönke, Anna Krook, Melissa L. Borg, Rebecca R. Miles, Mark R. Wade
Publikováno v:
Diabetes. 68(7)
The neuropeptide urocortin 2 (UCN2) and its receptor corticotropin-releasing hormone receptor 2 (CRHR2) are highly expressed in skeletal muscle and play a role in regulating energy balance and glucose metabolism. We investigated a modified UCN2 pepti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87cae7ff42babbca68b2c86cdd35ffd7
https://pubmed.ncbi.nlm.nih.gov/31010957
https://pubmed.ncbi.nlm.nih.gov/31010957
Autor:
Shuang Luo, Steven H. Zuckerman, John F. Carpenter, Dotzlaf Joe Edward, Mcclure Don B, Deborah L. Fisher, Yue-Wei Qian, Xiliang Wang, Aimin Lin, Victor J. Chen, Mariam Ehsani, Rebecca R. Miles
Publikováno v:
Hybridoma. 26:155-161
Folypolyglutamate synthetase (FPGS) plays a critical role in the cellular retention of both folates and antifolates. Resistance to antifolates is in part related to changes in FPGS enzyme activity and levels of messenger RNA, or in some instances, pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b0cc26ae2d43744b5267a8d6de54362
https://doi.org/10.1089/hyb.2007.004
https://doi.org/10.1089/hyb.2007.004
Autor:
S. Huang, T.A. Grese, Henry Uhlman Bryant, P. Chen, Masahiko Sato, Jude E. Onyia, J.A. Dodge, Leah M. Helvering, Shawn T. Estrem, Ernst R. Dow, A.G. Geiser, Rebecca R. Miles, David L. Halladay, S.A. Jones, M.D. Adrian, Y.L. Ma, John N. Calley, Tao Wei
Publikováno v:
Biology of Reproduction. 72:830-841
A detailed analysis of the differential effects of estrogen (E) compared to raloxifene (Ral), a selective estrogen receptor modulator (SERM), following estrogen receptor (ER) binding in gynecological tissues was conducted using gene microarrays, Nort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::826627eaf05aae36ec7bb127fba0f926
https://doi.org/10.1095/biolreprod.104.034595
https://doi.org/10.1095/biolreprod.104.034595
Autor:
Henry Uhlman Bryant, M. Zhang, Leah M. Helvering, N.H. Kulkarni, Sutada Lotinun, Charles A. Frolik, Jude E. Onyia, Yanfei L. Ma, Avudaiappan Maran, Rebecca R. Miles, Emily M. Ambrose, Peining Chen, Lawrence M. Gelbert, Tao Wei, Masahiko Sato, Ernst R. Dow, Xi Lin, David L. Halladay, Russell T. Turner, Shuguang Huang
Publikováno v:
Journal of Cellular Biochemistry. 95:403-418
Teriparatide, human PTH (1-34), a new therapy for osteoporosis, elicits markedly different skeletal responses depending on the treatment regimen. In order to understand potential mechanisms for this dichotomy, the present investigation utilized micro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c743b61513b4574818eb566546df622b
https://doi.org/10.1002/jcb.20438
https://doi.org/10.1002/jcb.20438
Novel and Selective Small Molecule Stimulators of Osteoprotegerin Expression Inhibit Bone Resorption
Autor:
Tina Fuson, Srinivasan Chandrasekhar, Rebecca R. Miles, Renee Emkey, David L. Halladay, Rachelle J. Sells Galvin, Yanping Xu, Ricky L. Cain, Henry Uhlman Bryant, T. John Martin, Kannan Thirunavukkarasu, Yanfei L. Ma, Qing Qiang Zeng, Jude E. Onyia, Xuhao Yang
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 309:369-379
Osteoprotegerin (OPG), a secreted member of the tumor necrosis factor receptor superfamily, is a potent inhibitor of osteoclast formation and bone resorption. Because OPG functions physiologically as a locally generated (paracrine) factor, we used hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bb15a45871691a6e00e4f1dfab2a7aa
https://doi.org/10.1124/jpet.103.057893
https://doi.org/10.1124/jpet.103.057893
Autor:
James P. Sluka, Rachelle J. Sells Galvin, L. Ma, L. V. Hale, Jude E. Onyia, J.M. Hock, David L. Halladay, S.R. Patanjali, R. F. Santerre, Rebecca R. Miles, L. Bloem
Publikováno v:
Journal of Cellular Biochemistry. 85:229-242
Parathyroid hormone (PTH) stimulates bone formation in both animals and humans, and the expression of a number of genes has been implicated in the mediation of this effect. To discover new bone factors that initiate and support this phenomenon, we us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::457bb5ee5dc27d54c442ced1108855b4
https://doi.org/10.1002/jcb.10129
https://doi.org/10.1002/jcb.10129
Analysis of regulator of G-protein signaling-2 (RGS-2) expression and function in osteoblastic cells
Autor:
Rebecca R. Miles, Chad D. Geringer, David L. Halladay, Jude E. Onyia, Kannan Thirunavukkarasu
Publikováno v:
Journal of Cellular Biochemistry. 85:837-850
Regulator of G-protein signaling-2 (RGS-2) belongs to a novel family of GTPase-activating proteins that rapidly turn-off G-protein coupled receptor signaling. RGS proteins contain a characteristic RGS domain by which they interact with the α-subunit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e201c185f768545f02cc48d2d719f9c
https://doi.org/10.1002/jcb.10176
https://doi.org/10.1002/jcb.10176
Autor:
R. L. Cain, Jude E. Onyia, David L. Halladay, Srinivasan Chandrasekhar, Yanfei L. Ma, T J Martin, Qingqiang Zeng, Xuhao Yang, Rebecca R. Miles
Publikováno v:
Endocrinology. 142:4047-4054
Continuous infusion of PTH in vivo results in active bone resorption. To investigate the molecular basis of the catabolic effect of PTH in vivo, we evaluated the role of OPG and RANKL, which are known to influence osteoclast formation and function. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f7257c4e6438fcb5681b313a530b973
https://doi.org/10.1210/endo.142.9.8356
https://doi.org/10.1210/endo.142.9.8356