Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Rebecca R Pasquarelli"'
Publikováno v:
PLoS Pathogens, Vol 20, Iss 7, p e1012411 (2024)
Toxoplasma gondii divides by endodyogeny, in which two daughter buds are formed within the cytoplasm of the maternal cell using the inner membrane complex (IMC) as a scaffold. During endodyogeny, components of the IMC are synthesized and added sequen
Externí odkaz:
https://doaj.org/article/ba983fdfa58d4acfba2671fe31539b06
Publikováno v:
PLoS Pathogens, Vol 19, Iss 10, p e1011707 (2023)
The inner membrane complex (IMC) of Toxoplasma gondii is essential for all phases of the parasite's life cycle. One of its most critical roles is to act as a scaffold for the assembly of daughter buds during replication by endodyogeny. While many dau
Externí odkaz:
https://doaj.org/article/380e8c347a2944668f3873a8e132e05c
Autor:
Jessica H. Chern, Rebecca R. Pasquarelli, Andy S. Moon, Allan L. Chen, Jihui Sha, James A. Wohlschlegel, Peter J. Bradley
Publikováno v:
mBio, Vol 12, Iss 5 (2021)
The inner membrane complex (IMC) is a peripheral membrane and cytoskeletal system that is organized into intriguing rectangular plates at the periphery of the parasite. The IMC plates are delimited by an array of IMC suture proteins that are tethered
Externí odkaz:
https://doaj.org/article/e8f95de681b742e3b129449f93965b2a
Publikováno v:
mBio, Vol 12, Iss 1 (2021)
The IMC is an important organelle that apicomplexan parasites use to maintain their intracellular lifestyle. While many IMC proteins have been identified, only a few central players that are essential for internal budding have been described and even
Externí odkaz:
https://doaj.org/article/82149a155c5143a0bb944984b336794c
Autor:
Peter S. Back, Andy S. Moon, Rebecca R. Pasquarelli, Hannah N. Bell, Juan A. Torres, Allan L. Chen, Jihui Sha, Ajay A. Vashisht, James A. Wohlschlegel, Peter J. Bradley
Publikováno v:
mBio. 14
The inner membrane complex (IMC) is a conserved structure across the Apicomplexa phylum, which includes obligate intracellular parasites that cause toxoplasmosis, malaria, and cryptosporidiosis. The IMC is critical for the parasite to maintain its in
Autor:
Andy S. Moon, Jihui Sha, Peter J. Bradley, Allan L. Chen, Rebecca R. Pasquarelli, Jessica H Chern, James A. Wohlschlegel
Publikováno v:
mBio, Vol 12, Iss 5 (2021)
mBio
mBio
The cytoskeleton of Toxoplasma gondii is composed of the inner membrane complex (IMC) and an array of underlying microtubules that provide support at the periphery of the parasite. Specific subregions of the IMC carry out distinct roles in replicatio
Autor:
Rebecca R. Pasquarelli, Justin J. Quan, Emily S. Cheng, Vivian Yang, Timmie A. Britton, Jihui Sha, James A. Wohlschlegel, Peter J. Bradley
Publikováno v:
mBio, Vol 15, Iss 11 (2024)
ABSTRACT Toxoplasma gondii possesses a highly polarized secretory pathway that contains both broadly conserved eukaryotic organelles and unique apicomplexan organelles, which play essential roles in the parasite’s lytic cycle. As in other eukaryote
Externí odkaz:
https://doaj.org/article/bd70e26450dd4669976e1a1d2699ae14