Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Rebecca Pratt"'
Autor:
Komal Sodhi, Rebecca Pratt, Xiaoliang Wang, Hari Vishal Lakhani, Sneha S. Pillai, Mishghan Zehra, Jiayan Wang, Lawrence Grover, Brandon Henderson, James Denvir, Jiang Liu, Sandrine Pierre, Thomas Nelson, Joseph I. Shapiro
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108438- (2023)
Externí odkaz:
https://doaj.org/article/07230521f1774019ad70438bd53bf348
Autor:
Komal Sodhi, Rebecca Pratt, Xiaoliang Wang, Hari Vishal Lakhani, Sneha S. Pillai, Mishghan Zehra, Jiayan Wang, Lawrence Grover, Brandon Henderson, James Denvir, Jiang Liu, Sandrine Pierre, Thomas Nelson, Joseph I. Shapiro
Publikováno v:
iScience, Vol 24, Iss 11, Pp 103262- (2021)
Summary: Recent studies suggest that a western diet may contribute to clinical neurodegeneration and dementia. Adipocyte-specific expression of the Na,K-ATPase signaling antagonist, NaKtide, ameliorates the pathophysiological consequences of murine e
Externí odkaz:
https://doaj.org/article/2616f0730c0a41648e1183cee566289c
Autor:
Komal Sodhi, Alexandra Nichols, Amrita Mallick, Rebecca L. Klug, Jiang Liu, Xiaoliang Wang, Krithika Srikanthan, Perrine Goguet-Rubio, Athar Nawab, Rebecca Pratt, Megan N. Lilly, Juan R. Sanabria, Zijian Xie, Nader G.Abraham, Joseph I. Shapiro
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/c1f2e92999da458e8a3e51890b71f75e
Autor:
Tatiyana Harris, Raluca Bugescu, Jaylyn Kelly, Anna Makela, Morgan Sotzen, Cheryl Sisk, Graham Atkin, Rebecca Pratt, Elahé Crockett, Gina Leinninger
Publikováno v:
Brain Sciences, Vol 10, Iss 12, p 975 (2020)
Lateral hypothalamic area (LHA) neurons expressing the neuropeptide orexin (OX) are implicated in obesity and anxio-depression. However, these neurons release OX as well as a host of other proteins that might contribute to normal physiology and disea
Externí odkaz:
https://doaj.org/article/c30a1adc6cc34bb0b6c252dc4fd4e619
Autor:
Athar Nawab, Xiaoliang Wang, Brian Snoad, Muhammad A. Chaudhry, Rebecca Pratt, Zijian Xie, Nader G. Abraham, Mishghan Zehra, Komal Sodhi, Jiang Liu, Hari Vishal Lakhani, Fang Bai, Cameron L. Cottrill, James Denvir, Joseph I. Shapiro, Juan Sanabria
Publikováno v:
J Am Soc Nephrol
Background Oxidative stress in adipocyte plays a central role in the pathogenesis of obesity as well as in the associated cardiovascular complications. The putative uremic toxin indoxyl sulfate induces oxidative stress and dramatically alters adipocy
Autor:
Rebecca Pratt, Thomas Nelson, James Denvir, Mishghan Zehra, Jiayan Wang, Sandrine V. Pierre, Hari Vishal Lakhani, Joseph I. Shapiro, Brandon J. Henderson, Lawrence M. Grover, Sneha S. Pillai, Jiang Liu, Xiaoliang Wang, Komal Sodhi
Publikováno v:
iScience
iScience, Vol 24, Iss 11, Pp 103262-(2021)
iScience, Vol 24, Iss 11, Pp 103262-(2021)
Summary Recent studies suggest that a western diet may contribute to clinical neurodegeneration and dementia. Adipocyte-specific expression of the Na,K-ATPase signaling antagonist, NaKtide, ameliorates the pathophysiological consequences of murine ex
Autor:
Brian Snoad, Nader G. Abraham, Cameron L. Cottrill, Jiang Liu, Austin S. Jelcick, Komal Sodhi, Athar Nawab, Niharika Bhardwaj, Zijian Xie, Cameron Brickman, Brandon J. Henderson, Juan Sanabria, Hari Vishal Lakhani, Rebecca Pratt, Joseph I. Shapiro
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-1 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
The protein-protein interactions amongst the Na/K-ATPase α1 subunit, c-Src, and caveolin-1 (cav-1) are essential for the Na/K-ATPase signaling functions. However, there are arguments concerning the interaction model. The present study aims to clarif
Autor:
Cameron Brickman, Jung Han Kim, Muhammad A. Chaudhry, Yanling Yan, Deepak Malhotra, Rebecca Pratt, Jiang Liu, Sandrine V. Pierre, Jiayan Wang, Gary O. Rankin, Fang Bai, Zijian Xie, Shuyan Sun, Ying Nie, Joseph I. Shapiro, Jazmin Carmon, Preeya T. Shah, Komal Sodhi
Publikováno v:
International Journal of Molecular Sciences
Volume 20
Issue 14
International Journal of Molecular Sciences, Vol 20, Iss 14, p 3495 (2019)
Volume 20
Issue 14
International Journal of Molecular Sciences, Vol 20, Iss 14, p 3495 (2019)
We have demonstrated that Na/K-ATPase acts as a receptor for reactive oxygen species (ROS), regulating renal Na+ handling and blood pressure. TALLYHO/JngJ (TH) mice are believed to mimic the state of obesity in humans with a polygenic background of t
Autor:
Rebecca Pratt, Hari Vishal Lakhani, Athar Nawab, Niharika Bhardwaj, Joseph I. Shapiro, Cameron L. Cottrill, Nader G. Abraham, Zijian Xie, Brian Snoad, Austin S. Jelcick, Cameron Brickman, Jiang Liu, Juan Sanabria, Brandon J. Henderson, Komal Sodhi
Publikováno v:
Scientific Reports. 9
Obesity has become a worldwide epidemic. We have previously reported that systemic administration of pNaKtide which targets the Na/K-ATPase oxidant amplification loop (NKAL) was able to decrease systemic oxidative stress and adiposity in mice fed a h