Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Rebecca Pastrana-Mena"'
Autor:
Brian B. Tarimo, Bernadette A. Hritzo, Henry Chun Hin Law, Dingyin Tao, Rebecca Pastrana-Mena, Stefan M. Kanzok, Joram J. Buza, Rhoel R. Dinglasan
Publikováno v:
BMC Research Notes, Vol 12, Iss 1, Pp 1-8 (2019)
Abstract Objective A fundamental understanding of redox homeostasis in Anopheles gambiae midgut cells under different oxidative conditions is missing. Such knowledge can aid in the development of new malaria transmission-blocking strategies aimed at
Externí odkaz:
https://doaj.org/article/d0d3e8ccdaf6478886791192068c385c
Autor:
Brian B. Tarimo, Henry Chun Hin Law, Dingyin Tao, Rebecca Pastrana-Mena, Stefan M. Kanzok, Joram J. Buza, Rhoel R. Dinglasan
Publikováno v:
Proteomes, Vol 6, Iss 4, p 47 (2018)
Paraquat is a potent superoxide (O2−)-inducing agent that is capable of inducing an oxidative imbalance in the mosquito midgut. This oxidative imbalance can super-stress the malaria parasite, leading to arrested development in the mosquito midgut a
Externí odkaz:
https://doaj.org/article/78e2821877884ec6a0a17a468082073e
Autor:
Joel Vega-Rodríguez, Rebecca Pastrana-Mena, Keila N Crespo-Lladó, José G Ortiz, Iván Ferrer-Rodríguez, Adelfa E Serrano
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0128212 (2015)
Malaria is one of the most devastating parasitic diseases worldwide. Plasmodium drug resistance remains a major challenge to malaria control and has led to the re-emergence of the disease. Chloroquine (CQ) and artemisinin (ART) are thought to exert t
Externí odkaz:
https://doaj.org/article/f7eb486b4c66480788295d76f55c2d1b
Autor:
Derrick K Mathias, Rebecca Pastrana-Mena, Elisabetta Ranucci, Dingyin Tao, Paolo Ferruti, Corrie Ortega, Gregory O Staples, Joseph Zaia, Eizo Takashima, Takafumi Tsuboi, Natalie A Borg, Luisella Verotta, Rhoel R Dinglasan
Publikováno v:
PLoS Pathogens, Vol 9, Iss 11, p e1003757 (2013)
Malaria transmission-blocking (T-B) interventions are essential for malaria elimination. Small molecules that inhibit the Plasmodium ookinete-to-oocyst transition in the midgut of Anopheles mosquitoes, thereby blocking sporogony, represent one approa
Externí odkaz:
https://doaj.org/article/f0829bc3f99e45feb075814ea5c92d22
Autor:
Joel Vega-Rodríguez, Blandine Franke-Fayard, Rhoel R. Dinglasan, Chris J. Janse, Rebecca Pastrana-Mena, Andrew P. Waters, Isabelle Coppens, José F. Rodríguez-Orengo, Prakash Srinivasan, Marcelo Jacobs-Lorena, Adelfa E. Serrano
Publikováno v:
PLoS Pathogens, Vol 5, Iss 6 (2009)
Externí odkaz:
https://doaj.org/article/155fcef139394074a0d71ad8b8022101
Autor:
Joel Vega-Rodríguez, Blandine Franke-Fayard, Rhoel R Dinglasan, Chris J Janse, Rebecca Pastrana-Mena, Andrew P Waters, Isabelle Coppens, José F Rodríguez-Orengo, Prakash Srinivasan, Marcelo Jacobs-Lorena, Adelfa E Serrano
Publikováno v:
PLoS Pathogens, Vol 5, Iss 2, p e1000302 (2009)
Infection of red blood cells (RBC) subjects the malaria parasite to oxidative stress. Therefore, efficient antioxidant and redox systems are required to prevent damage by reactive oxygen species. Plasmodium spp. have thioredoxin and glutathione (GSH)
Externí odkaz:
https://doaj.org/article/425bfba860d9447ba5c84dcefa36255b
Autor:
Stefan M. Kanzok, Brian B. Tarimo, Rhoel R. Dinglasan, Joram Buza, Dingyin Tao, Henry Chun Hin Law, Rebecca Pastrana-Mena, Bernadette Hritzo
Publikováno v:
BMC Research Notes, Vol 12, Iss 1, Pp 1-8 (2019)
BMC Research Notes
BMC Research Notes
Objective A fundamental understanding of redox homeostasis in Anopheles gambiae midgut cells under different oxidative conditions is missing. Such knowledge can aid in the development of new malaria transmission-blocking strategies aimed at disruptin
Autor:
Joram J. Buza, Rebecca Pastrana-Mena, Dingyin Tao, Stefan M. Kanzok, Brian B. Tarimo, Rhoel R. Dinglasan, Henry Chun Hin Law
Publikováno v:
Proteomes, Vol 6, Iss 4, p 47 (2018)
Proteomes
Volume 6
Issue 4
Proteomes
Volume 6
Issue 4
Paraquat is a potent superoxide (O2&minus
)-inducing agent that is capable of inducing an oxidative imbalance in the mosquito midgut. This oxidative imbalance can super-stress the malaria parasite, leading to arrested development in the mosquito
)-inducing agent that is capable of inducing an oxidative imbalance in the mosquito midgut. This oxidative imbalance can super-stress the malaria parasite, leading to arrested development in the mosquito
Autor:
Derrick K. Mathias, Beatrice Trucchi, Krithika Rajaram, Jonas G. King, Rebecca Pastrana-Mena, Luisella Verotta, Rhoel R. Dinglasan, Michael J. Delves, Rebecca Yee
The evolution of drug resistance is a recurrent problem that has plagued efforts to treat and control malaria. Recent emergence of artemisinin resistance in Southeast Asia underscores the need to develop novel antimalarials and identify new targetabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93c2bf6dc598845def313684501501ad
https://europepmc.org/articles/PMC6503959/
https://europepmc.org/articles/PMC6503959/
Autor:
Rhoel R. Dinglasan, Yuan C. Lee, Jennifer Hou, Juliette G. Jardim, Rebecca Pastrana-Mena, Noboru Tomiya
Publikováno v:
Bioorganic & Medicinal Chemistry. 21:5275-5281
We have synthesized poly-γ-glutamic acid (PGA) modified with a synthetic trivalent glyco-ligand (TriGalNAc) for the hepatocyte asialoglycoprotein receptor (ASGP-R). We investigated in vivo distribution of unmodified PGA and TriGalNAc-modified PGA (T