Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Rebecca P. Wu"'
Autor:
Steven D. Levin, Lawrence S. Evans, Susan Bort, Erika Rickel, Katherine E. Lewis, Rebecca P. Wu, Joseph Hoover, Sean MacNeil, David La, Martin F. Wolfson, Mark W. Rixon, Stacey R. Dillon, Michael G. Kornacker, Ryan Swanson, Stanford L. Peng
Publikováno v:
Frontiers in Immunology, Vol 10 (2020)
Immunoglobulin superfamily member (IgSF) proteins play a significant role in regulating immune responses with surface expression on all immune cell subsets, making the IgSF an attractive family of proteins for therapeutic targeting in human diseases.
Externí odkaz:
https://doaj.org/article/bed901c0bf43422ba8dc0a6914b60717
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 13, Iss 3, Pp 676-679 (2017)
Background: The human papillomavirus (HPV) vaccine is recommended for male and female recipients aged 9–26 years, and is effective in preventing HPV infection and cancer precursors. However, there is variability in immunogenicity among recipients a
Externí odkaz:
https://doaj.org/article/b162d31df82b4a0083f702e08f7a5cbd
Autor:
Rebecca P. Wu, Jane H. Buckner, Heather Shilling, Megan Tatum, Paul L. Bollyky, Mary Rieck, Isabelle Muller, S. Alice Long, Jhon Chun Ho
Publikováno v:
The Journal of Immunology. 187:3511-3520
Low Ag dose promotes induction and persistence of regulatory T cells (Tregs) in mice, yet few studies have addressed the role of Ag dose in the induction of adaptive CD4+FOXP3+ Tregs in humans. To this end, we examined the level of FOXP3 expression i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec150772b9ba0a8031d229333eb91967
https://doi.org/10.4049/jimmunol.1003880
https://doi.org/10.4049/jimmunol.1003880
Autor:
S. Alice Long, Paul L. Bollyky, Gregory E. Holt, Anton Preisinger, Ben A. Falk, Brandon Teng, Nathan Standifer, Cindy Fang Xie, Gerald T. Nepom, John A. Gebe, Kathleen R. Braun, Robert B. Vernon, Peter L. Samuels, Rebecca P. Wu, James D. Lord, Thomas N. Wight
Publikováno v:
Proceedings of the National Academy of Sciences. 108:7938-7943
We describe a role for ECM as a biosensor for inflammatory microenvironments that plays a critical role in peripheral immune tolerance. We show that hyaluronan (HA) promotes induction of Foxp3- IL-10–producing regulatory T cells (TR1) from conventi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20da92284fef53c7c711f25eb44927aa
https://doi.org/10.1073/pnas.1017360108
https://doi.org/10.1073/pnas.1017360108
Autor:
Christina K. Chan, Brian Kinsella, Rebecca P. Wu, Stephen P. Evanko, Paul L. Bollyky, Thomas N. Wight, Brandon Teng, Helena Reijonen, Kathy R. Braun, John A. Gebe, Kelly Guebtner, Gerald T. Nepom, S. Alice Long, Susan Potter-Perigo
Publikováno v:
Cellular & Molecular Immunology. 7:211-220
Hyaluronan (HA) production by dendritic cells (DCs) is known to promote antigen presentation and to augment T-cell activation and proliferation. We hypothesized that pericellular HA can function as intercellular 'glue' directly mediating T cell-DC bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3c9f5673bc1de9a4d66fcbcf6b70a3c
https://doi.org/10.1038/cmi.2010.9
https://doi.org/10.1038/cmi.2010.9
Autor:
Paul L. Bollyky, Jane H. Buckner, Ben A. Falk, Stephen P. Evanko, Thomas N. Wight, Kathy R. Braun, S. Alice Long, Anton Preisinger, Rebecca P. Wu, Gerald T. Nepom
Publikováno v:
The Journal of Immunology. 183:2232-2241
Work by our group and others has demonstrated a role for the extracellular matrix receptor CD44 and its ligand hyaluronan in CD4+CD25+ regulatory T cell (Treg) function. Herein, we explore the mechanistic basis for this observation. Using mouse FoxP3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0aa4397e6853aa5775a2afdebb78ed7
https://doi.org/10.4049/jimmunol.0900191
https://doi.org/10.4049/jimmunol.0900191
Autor:
Rebecca P. Wu, Derek S. Youngblood, Candace E. Lovejoy, Hong M. Moulton, Jed N. Hassinger, Michelle H. Nelson, Patrick L. Iversen
Publikováno v:
Nucleic Acids Research
Arginine-rich cell-penetrating peptides (CPPs) are promising transporters for intracellular delivery of antisense morpholino oligomers (PMO). Here, we determined the effect of L-arginine, D-arginine and non-alpha amino acids on cellular uptake, splic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e16ee897677a355b7a7ac59ca8559965
http://europepmc.org/articles/PMC1976451
http://europepmc.org/articles/PMC1976451
Autor:
Derek S. Youngblood, Bernard Lebleu, Hong M. Moulton, Paul Prevot, Philippe Clair, Rebecca P. Wu, Saïd Abes, Patrick L. Iversen
Publikováno v:
Journal of Controlled Release. 116:304-313
The efficient and non-toxic nuclear delivery of steric-block oligonucleotides (ON) is a prerequisite for therapeutic strategies involving splice correction or exon skipping. Cationic cell penetrating peptides (CPPs) have given rise to much interest f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d92639ad41ad384c5aaa6fb3da5fe5c5
https://doi.org/10.1016/j.jconrel.2006.09.011
https://doi.org/10.1016/j.jconrel.2006.09.011
Autor:
Chester Ni, Carla J. Greenbaum, Jerill Thorpe, Vivian H. Gersuk, Srinath Sanda, Ivana Durinovic-Belló, Nicholas Jospe, Rebecca P. Wu, Gerald T. Nepom
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 5, p e98074 (2014)
PLoS ONE, Vol 9, Iss 5, p e98074 (2014)
Fate determination for autoreactive T cells relies on a series of avidity-dependent interactions during T cell selection, represented by two general types of signals, one based on antigen expression and density during T cell development, and one base
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00e5371d4ba6e8fae817e7022fe52117
https://pubmed.ncbi.nlm.nih.gov/24844227
https://pubmed.ncbi.nlm.nih.gov/24844227
Autor:
Rebecca P. Wu, Paul L. Bollyky, Jane H. Buckner, Thomas N. Wight, Ben A. Falk, Gerald T. Nepom
The authors describe the immunoregulatory contributions of intact versus fragmented hyaluronan, a prominent component of the extracellular matrix. The composition of the ECM provides contextual cues to leukocytes in inflamed and healing tissues. One
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62a0e6129b7411062ad25f780d327ea2
https://europepmc.org/articles/PMC2735281/
https://europepmc.org/articles/PMC2735281/
