Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Rebecca P Hughey"'
Autor:
Xiaoqian eQian, Xuechen eLi, Titilayo O Ilori, Janet D. Klein, Rebecca P Hughey, Cong-jun eLi, Abdel A Alli, Zhengyu eGuo, Peng eYu, Xiang eSong, Guangping eChen
Publikováno v:
Frontiers in Physiology, Vol 6 (2015)
The UT-A1 urea transporter is crucial to the kidney’s ability to generate concentrated urine. Native UT-A1 from kidney inner medulla (IM) is a heavily glycosylated protein with two glycosylation forms of 97 and 117 kDa. In diabetes, UT-A1 protein a
Externí odkaz:
https://doaj.org/article/653c6cd45f3d4297b5fb33925d6fb5dc
Autor:
Andrew J. Nickerson, Stephanie M. Mutchler, Shaohu Sheng, Natalie A. Cox, Evan C. Ray, Ossama B. Kashlan, Marcelo D. Carattino, Allison L. Marciszyn, Aaliyah Winfrey, Sebastien Gingras, Annet Kirabo, Rebecca P. Hughey, Thomas R. Kleyman
Publikováno v:
JCI Insight, Vol 8, Iss 21 (2023)
Epithelial Na+ channels (ENaCs) control extracellular fluid volume by facilitating Na+ absorption across transporting epithelia. In vitro studies showed that Cys-palmitoylation of the γENaC subunit is a major regulator of channel activity. We tested
Externí odkaz:
https://doaj.org/article/87119383c71c4777963a46201899f61f
Autor:
Corry D. Bondi, Brittney M. Rush, Hannah L. Hartman, Jiaxuan Wang, Mohammad M. Al-Bataineh, Rebecca P. Hughey, Roderick J. Tan
Publikováno v:
Antioxidants, Vol 11, Iss 9, p 1810 (2022)
Acute kidney injury (AKI) is a rapid decline in renal function and can occur after ischemia/reperfusion injury (IRI) to the tubular epithelia. The nuclear factor erythroid-2-related factor 2 (NRF2) pathway protects against AKI and AKI-to-chronic kidn
Externí odkaz:
https://doaj.org/article/4cb02811a4ee47ee935911835864e619
Autor:
Zaichuan Mi, Rebecca P. Hughey, Carol L. Kinlough, Stephanie M. Mutchler, David R. Emlet, Mohammad M. Al-bataineh, Edwin K. Jackson, John A. Kellum
Publikováno v:
Am J Physiol Renal Physiol
Cell-associated kidney injury molecule-1 (KIM-1) exerts an anti-inflammatory role following kidney injury by mediating efferocytosis and downregulating the NF-κB pathway. KIM-1 cleavage blunts its anti-inflammatory activities. We reported that Mucin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9a900ae47ec8af43e40a0a87eb15135
https://doi.org/10.1152/ajprenal.00127.2021
https://doi.org/10.1152/ajprenal.00127.2021
Autor:
Mohammad M. Al-bataineh, Carol L. Kinlough, Allison Marciszyn, Tracey Lam, Lorena Ye, Kendrah Kidd, Joseph C. Maggiore, Paul A. Poland, Anthony Bleyer, Daniel J. Bain, Thomas R. Kleyman, Rebecca P. Hughey, Evan C. Ray
SUMMARYPolymorphism of the gene encoding mucin 1 (MUC1) is associated with skeletal and dental phenotypes in human genomic studies. Animals lacking MUC1 exhibit mild reduction in bone density. These phenotypes could be a consequence of modulation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::131409c414b8e99712c2ad42c9d0eb75
https://doi.org/10.1101/2022.10.22.513333
https://doi.org/10.1101/2022.10.22.513333
Autor:
Evan C. Ray, Mohammad Al‐Bataineh, Tracey Lam, Carol C. Kinlough, Allison L. Marciszyn, Jenna Barbour, Irina Tourkova, Harry C. Blair, Thomas R. Kleyman, Rebecca P. Hughey
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::339369954dc9cfcef0ebcb5ffcc63533
https://doi.org/10.1096/fasebj.2022.36.s1.r3809
https://doi.org/10.1096/fasebj.2022.36.s1.r3809
Autor:
Seth L. Alper, Rebecca P. Hughey, Hannah C. Ainsworth, Victoria Robins, Petr Vylet'al, Tomáš Zima, Alena Vrbacká, Kateřina Hodaňová, Hana Hartmannová, Anthony J. Bleyer, Kendrah Kidd, Martina Živná, Carl D. Langefeld, Abbigail Taylor, Drahomira Springer, Katrice Howard, Maegan Harden, Anna Přistoupilová, Stanislav Kmoch, Ibrahim Bitar, Steven M. Harrison, Niall J. Lennon, Lauren Martin, Veronika Baresova
Publikováno v:
American Journal of Nephrology. 52:378-387
Introduction: Patients with ADTKD-MUC1 have one allele producing normal mucin-1 (MUC1) and one allele producing mutant MUC1, which remains intracellular. We hypothesized that ADTKD-MUC1 patients, who have only 1 secretory-competent wild-type MUC1 all
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2cd96461c335888b322fa024cce5a37c
https://doi.org/10.1159/000515810
https://doi.org/10.1159/000515810
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2442
Galectins are best known for their ability to bind glycoconjugates containing β-galactose, but classification of these small proteins within the galectin family is also defined by amino acid homology within structural domains and exon/intron junctio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b5eee448aa43a430d5b5531810666642
https://pubmed.ncbi.nlm.nih.gov/35320518
https://pubmed.ncbi.nlm.nih.gov/35320518
Autor:
Mohammad M. Al-bataineh, Carol L. Kinlough, Allison Marciszyn, Tracey Lam, Lorena Ye, Kendrah Kidd, Joseph C. Maggiore, Paul A. Poland, Stanislav Kmoch, Anthony Bleyer, Daniel J. Bain, Nicolas Montalbetti, Thomas R. Kleyman, Rebecca P. Hughey, Evan C. Ray
Publikováno v:
Journal of Biological Chemistry. 299:102925
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f71f795101809f10ef4c93d74651c706
https://doi.org/10.1016/j.jbc.2023.102925
https://doi.org/10.1016/j.jbc.2023.102925
Autor:
John A. Kellum, Zaichuan Mi, Carol L. Kinlough, Mohammad M. Al-bataineh, David R. Emlet, Edwin K. Jackson, Rebecca P. Hughey
Publikováno v:
The FASEB Journal. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc09b3bd162350abd862a84d03180b8b
https://doi.org/10.1096/fasebj.2021.35.s1.04311
https://doi.org/10.1096/fasebj.2021.35.s1.04311