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pro vyhledávání: '"Rebecca Orha"'
Autor:
Sarah L Ash, Rebecca Orha, Holly Mole, Meg Dinesh-Kumar, Steven P Lee, Frances K Turrell, Clare M Isacke
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 2 (2024)
Background Targeting of solid cancers with chimeric antigen receptor (CAR)-T cells is limited by the lack of suitable tumor-specific antigens and the immunosuppressive, desmoplastic tumor microenvironment that impedes CAR-T cell infiltration, activit
Externí odkaz:
https://doaj.org/article/050b5733a92d4347b81bd4fe65768fbc
Autor:
Frances K. Turrell, Rebecca Orha, Naomi J. Guppy, Andrea Gillespie, Matthew Guelbert, Chris Starling, Syed Haider, Clare M. Isacke
Publikováno v:
Nature Cancer. 4:468-484
Patients with estrogen receptor (ER)-positive breast cancer are at risk of metastatic relapse for decades after primary tumor resection and treatment, a consequence of dormant disseminated tumor cells (DTCs) reawakening at secondary sites. Here we us