Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Rebecca Olin"'
Autor:
Courtney D. DiNardo, Rebecca Olin, Eunice S. Wang, Barry Skikne, Joseph Rosenthal, Prasanna Kumar, Hiroyuki Sumi, Yoshiyuki Hizukuri, Ying Hong, Parul Patel, Takahiko Seki, Tao Duan, Arnaud Lesegretain, Michael Andreeff
Publikováno v:
Cancer Medicine, Vol 13, Iss 14, Pp n/a-n/a (2024)
Abstract Background Mouse double minute‐2 homolog (MDM2) plays a key role in downregulating p53 activity in hematologic malignancies, and its overexpression is associated with poor outcomes. Methods This phase 1 study assessed the safety and effica
Externí odkaz:
https://doaj.org/article/e364b932b764470888635e68d3510be6
Autor:
Daniel A. Pollyea, Jessica K. Altman, Rita Assi, Dale Bixby, Amir T. Fathi, James M. Foran, Ivana Gojo, Aric C. Hall, Brian A. Jonas, Ashwin Kishtagari, Jeffrey Lancet, Lori Maness, James Mangan, Gabriel Mannis, Guido Marcucci, Alice Mims, Kelsey Moriarty, Moaath Mustafa Ali, Jadee Neff, Reza Nejati, Rebecca Olin, Mary-Elizabeth Percival, Alexander Perl, Amanda Przespolewski, Dinesh Rao, Farhad Ravandi, Rory Shallis, Paul J. Shami, Eytan Stein, Richard M. Stone, Kendra Sweet, Swapna Thota, Geoffrey Uy, Pankit Vachhani, Carly J. Cassara, Deborah A. Freedman-Cass, Katie Stehman
Publikováno v:
Journal of the National Comprehensive Cancer Network. 21:503-513
Acute myeloid leukemia (AML) is a heterogeneous hematologic malignancy characterized by the clonal expansion of myeloid blasts in the peripheral blood, bone marrow, and/or other tissues. It is the most common form of acute leukemia among adults and a
Autor:
Naveen Pemmaraju, Hagop Kantarjian, Kendra Sweet, Eunice Wang, Jayastu Senapati, Nathaniel R. Wilson, Marina Konopleva, Arthur E. Frankel, Vikas Gupta, Ruben Mesa, Matthew Ulrickson, Edward Gorak, Sumeet Bhatia, Tulin Budak-Alpdogan, James Mason, Maria Teresa Garcia-Romero, Norma Lopez-Santiago, Gabriela Cesarman-Maus, Pankit Vachhani, Sangmin Lee, Vijaya Raj Bhatt, William Blum, Roland B. Walter, Dale Bixby, Ivana Gojo, Madeleine Duvic, Raajit K. Rampal, Marcos de Lima, James Foran, Amir T. Fathi, Aric Cameron Hall, Meagan A. Jacoby, Jeffrey Lancet, Gabriel Mannis, Anthony S. Stein, Alice Mims, David Rizzieri, Rebecca Olin, Alexander Perl, Gary Schiller, Paul Shami, Richard M. Stone, Stephen Strickland, Matthew J. Wieduwilt, Naval Daver, Farhad Ravandi, Sumithira Vasu, Monica Guzman, Gail J. Roboz, Joseph Khoury, Muzaffar Qazilbash, Phyu P. Aung, Branko Cuglievan, Yazan Madanat, Mohamed A. Kharfan-Dabaja, Anna Pawlowska, Justin Taylor, Martin Tallman, Prajwal Dhakal, Andrew A. Lane
Publikováno v:
Blood. 141:567-578
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematologic malignancy with historically poor outcomes and no worldwide consensus treatment approach. Unique among most hematologic malignancies for its frequent cutaneous involvement, BP
Autor:
Sarah A. Wall, Rebecca Olin, Vijaya Bhatt, Saurabh Chhabra, Pashna Munshi, Eileen Hacker, Shahrukh Hashmi, Hailey Hassel, Dianna Howard, Reena Jayani, Richard Lin, Shannon McCurdy, Asmita Mishra, Hemant Murthy, Uday Popat, William Wood, Ashley E. Rosko, Andrew Artz
Publikováno v:
Transplantation and Cellular Therapy.
Autor:
Charalambos Andreadis, Frank McCormick, Gabriela K. Fragiadakis, Pamela N. Munster, David P. Carbone, Chun J. Ye, Vivian Weinberg, Michael Flanders, Emma McMahon, Karin M. Gaensler, Peter H. Sayre, Thomas G. Martin, Lloyd E. Damon, Rebecca Olin, Gabriel N. Mannis, Matthew Settles, Aaron C. Logan, Tommy Jiang, Blythe Durbin-Johnson, Arjun A. Rao, Gregory K. Behbehani, Ravi K. Patel, Bradley W. Blaser, Victoria E. Wang
Supplementary Data from Inhibition of MET Signaling with Ficlatuzumab in Combination with Chemotherapy in Refractory AML: Clinical Outcomes and High-Dimensional Analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e9274c477d2ab2f5535764c6f7ffb71
https://doi.org/10.1158/2643-3230.22543692
https://doi.org/10.1158/2643-3230.22543692
Autor:
Charalambos Andreadis, Frank McCormick, Gabriela K. Fragiadakis, Pamela N. Munster, David P. Carbone, Chun J. Ye, Vivian Weinberg, Michael Flanders, Emma McMahon, Karin M. Gaensler, Peter H. Sayre, Thomas G. Martin, Lloyd E. Damon, Rebecca Olin, Gabriel N. Mannis, Matthew Settles, Aaron C. Logan, Tommy Jiang, Blythe Durbin-Johnson, Arjun A. Rao, Gregory K. Behbehani, Ravi K. Patel, Bradley W. Blaser, Victoria E. Wang
Acute myeloid leukemia (AML) patients refractory to induction therapy or relapsed within 1 year have poor outcomes. Autocrine production of hepatocyte growth factor by myeloid blasts drives leukemogenesis in preclinical models. A phase Ib trial evalu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c6723e49382eda7eadaaae9301736b6
https://doi.org/10.1158/2643-3230.c.6550365.v1
https://doi.org/10.1158/2643-3230.c.6550365.v1
Autor:
Daniel A, Pollyea, Dale, Bixby, Alexander, Perl, Vijaya Raj, Bhatt, Jessica K, Altman, Frederick R, Appelbaum, Marcos, de Lima, Amir T, Fathi, James M, Foran, Ivana, Gojo, Aric C, Hall, Meagan, Jacoby, Jeffrey, Lancet, Gabriel, Mannis, Guido, Marcucci, Michael G, Martin, Alice, Mims, Jadee, Neff, Reza, Nejati, Rebecca, Olin, Mary-Elizabeth, Percival, Thomas, Prebet, Amanda, Przespolewski, Dinesh, Rao, Farhad, Ravandi-Kashani, Paul J, Shami, Richard M, Stone, Stephen A, Strickland, Kendra, Sweet, Pankit, Vachhani, Matthew, Wieduwilt, Kristina M, Gregory, Ndiya, Ogba, Martin S, Tallman
Publikováno v:
Journal of the National Comprehensive Cancer Network : JNCCN. 19(1)
The NCCN Guidelines for Acute Myeloid Leukemia (AML) provide recommendations for the diagnosis and treatment of adults with AML based on clinical trials that have led to significant improvements in treatment, or have yielded new information regarding
Autor:
Alexander E, Perl, Giovanni, Martinelli, Jorge E, Cortes, Andreas, Neubauer, Ellin, Berman, Stefania, Paolini, Pau, Montesinos, Maria R, Baer, Richard A, Larson, Celalettin, Ustun, Francesco, Fabbiano, Harry P, Erba, Antonio, Di Stasi, Robert, Stuart, Rebecca, Olin, Margaret, Kasner, Fabio, Ciceri, Wen-Chien, Chou, Nikolai, Podoltsev, Christian, Recher, Hisayuki, Yokoyama, Naoko, Hosono, Sung-Soo, Yoon, Je-Hwan, Lee, Timothy, Pardee, Amir T, Fathi, Chaofeng, Liu, Nahla, Hasabou, Xuan, Liu, Erkut, Bahceci, Mark J, Levis
Publikováno v:
The New England journal of medicine. 381(18)
Patients with relapsed or refractory acute myeloid leukemia (AML) with mutations in the FMS-like tyrosine kinase 3 gene (In a phase 3 trial, we randomly assigned adults with relapsed or refractoryOf 371 eligible patients, 247 were randomly assigned t
Autor:
Gautam, Borthakur, Leslie, Popplewell, Michael, Boyiadzis, James, Foran, Uwe, Platzbecker, Norbert, Vey, Roland B, Walter, Rebecca, Olin, Azra, Raza, Aristoteles, Giagounidis, Aref, Al-Kali, Elias, Jabbour, Tapan, Kadia, Guillermo, Garcia-Manero, John W, Bauman, Yuehui, Wu, Yuan, Liu, Dan, Schramek, Donna S, Cox, Paul, Wissel, Hagop, Kantarjian
Publikováno v:
Cancer. 122(12)
RAS/RAF/mitogen-activated protein kinase activation is common in myeloid malignancies. Trametinib, a mitogen-activated protein kinase kinase 1 (MEK1)/MEK2 inhibitor with activity against multiple myeloid cell lines at low nanomolar concentrations, wa