Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Rebecca N Marnane"'
Autor:
William R. Wilson, Kathleen G. Mountjoy, Ralph J. Stevenson, Moana Tercel, Stephen Mark Stribbling, Rebecca N. Marnane, Guo-Liang Lu, William A. Denny, Michele A. Tatnell
Publikováno v:
Bioorganic & Medicinal Chemistry. 20:734-749
Quaternary salt analogues based on the DNA minor groove binder and adenine N3 alkylating agent 5-amino-1-(chloromethyl)-1,2-dihydro-3H-benz[e]indole (aminoCBI) show remarkable effects on the body weight of mice (a long-term failure to gain weight rel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7a59b56860dad57bad5eeb71bf4b9d8
https://doi.org/10.1016/j.bmc.2011.12.007
https://doi.org/10.1016/j.bmc.2011.12.007
Autor:
Hua Yao, Rebecca N. Marnane, Nicholas B. Sorensen, Joseph W. Scott, Christine G. Joseph, Carrie Haskell-Luevano, Kathleen G. Mountjoy
Publikováno v:
Peptides. 31:2304-2313
The melanocortin system has been implicated in a multitude of physiological pathways including obesity, satiety, energy homeostasis, sexual behavior, pigmentation, sodium regulation, hypertension, and many others. Based upon studies of the endogenous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19e88312bb856fb7a49ae70e3a7c74bd
https://doi.org/10.1016/j.peptides.2010.08.025
https://doi.org/10.1016/j.peptides.2010.08.025
Autor:
Robert B. Elliott, Cécile E. Duchesnes, Rebecca N. Marnane, Jéssica Rodrigues, Michele A. Tatnell, George L. Wolff, Kathleen G. Mountjoy, Nikki Beckman, Beau Pontre, Jürgen K. Naggert, Angela Halim, Alistair W. Stewart
Publikováno v:
Physiological Genomics. 37:164-174
The study of spontaneous mutations in mice over the last century has been fundamental to our understanding of normal physiology and mechanisms of disease. Here we studied the phenotype and genotype of a novel mouse model we have called the New Zealan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9a43f10baa91d4692fe4a3c59ef195d
https://doi.org/10.1152/physiolgenomics.90336.2008
https://doi.org/10.1152/physiolgenomics.90336.2008
Autor:
Kathleen G. Mountjoy, Ric Broadhurst, C.-S. Jenny Wu, Philip B. Daniel, Chathurini Fernando, Rebecca N. Marnane
Publikováno v:
Molecular and Cellular Endocrinology. 239:63-71
The melanocortin 4 receptor (MC4R) plays a critical role in the regulation of energy homeostasis, and the MC4R knockout mouse and humans with MC4R defective mutations in only one allele indicate that there is a gene dosage effect. Alterations in gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f14b52bae15255d9b57abe4811e41f7c
https://doi.org/10.1016/j.mce.2005.03.013
https://doi.org/10.1016/j.mce.2005.03.013
Autor:
William R. Wilson, Angela Halim, Cécile E. Duchesnes, Guo-Liang Lu, Rebecca N. Marnane, Kathleen G. Mountjoy, Moana Tercel, Truong M, Michele A. Tatnell, William A. Denny, Ralph J. Stevenson
Publikováno v:
International journal of obesity (2005). 37(5)
We describe how a single intraperitoneal injection of an indoline-derived drug (SN 28127) reduced mouse body weight (25–45% loss) and adipose tissue mass (∼75%). The reductions in body weight peaked at ∼21–28 days post drug injection and were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2130485c9d6c5c1d2822a8b86bb7479
https://pubmed.ncbi.nlm.nih.gov/22732909
https://pubmed.ncbi.nlm.nih.gov/22732909
