Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Rebecca Merica"'
Autor:
Lydia Navarrete-Galvan, Michael Guglielmo, Judith Cruz Amaya, Julie Smith-Gagen, Vincent C. Lombardi, Rebecca Merica, Dorothy Hudig
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-13 (2022)
Abstract Background The NK cell line NK-92 and its genetically modified variants are receiving attention as immunotherapies to treat a range of malignancies. However, since NK-92 cells are themselves tumors, they require irradiation prior to transfer
Externí odkaz:
https://doaj.org/article/08b208ea7b0644029d4d0450d419a938
Autor:
Lydia T Navarrete-Galvan, Michael Guglielmo, Judith Cruz Amaya, Julie Smith-Gagen, Vincent C. Lombardi, Rebecca Merica, Dorothy Hudig
Publikováno v:
Journal of translational medicine. 20(1)
BackgroundThe NK cell line NK-92 and its genetically modified variants are receiving attention as immunotherapies to treat a range of malignancies. However, since NK-92 cells are themselves tumors, they require irradiation prior to transfer and are p
Autor:
Lydia T Navarrete-Galvan, Michael Guglielmo, Judith Cruz Amaya, Rebecca Merica, Julie Smith-Gagen, Vincent C Lombardi, Dorothy Hudig
Publikováno v:
The Journal of Immunology. 208:62.03-62.03
Adoptively transferred NK-92 cells and genetically modified variants must undergo irradiation to prevent proliferation, since NK-92 cells are themselves tumors. This malignant quality also makes NK-92 cells susceptible to attack by patients’ NK cel
Autor:
Lydia T Navarrete-Galvan, Michael Guglielmo, Alexander Sung, Julie Smith-Gagen, Vincent Lombardi, Rebecca Merica, Dorothy Hudig
Publikováno v:
The Journal of Immunology. 206:57.09-57.09
The NK cell line NK-92 and transgenic variants are receiving attention as adoptive transfer immunotherapies to treat a range of malignancies. However, since NK-92s are themselves tumors, they require irradiation prior to transfer and are potentially
Autor:
Alexander P Sung, Lydia T Navarrete-Galvan, Michael Guglielmo, Julie Smith-Gagen, Douglas D Redelman, Rebecca Merica, Dorothy Hudig
Publikováno v:
The Journal of Immunology. 204:148.44-148.44
Serial killers are more desirable than single-hit attackers when it comes to treating cancer. Antibody-dependent cell-mediated cytotoxicity (ADCC) mediated by NK lymphocytes is a significant component of many monoclonal antibody anti-cancer immunothe
Autor:
Lydia T Navarrete-Galvan, Michael Guglielmo, Julie Smith-Gagen, Rebecca Merica, Vincent C Lombardi, Dorothy Hudig
Publikováno v:
The Journal of Immunology. 204:88.5-88.5
Serial killers are much more productive than one-hit wonders, especially when it comes to killing cancer. Natural killer lymphocytes are significant cells in many anti-cancer immunotherapies, such as monoclonal antibody based- and adoptive cell trans
Autor:
Dorothy Hudig, Keli Tokunaga, Alexander P Sung, Michael J Guglielmo, Julie Smith-Gagen, Rebecca Merica, Doug Redelman
Publikováno v:
The Journal of Immunology. 202:182.50-182.50
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is characterized by fatigue that does not improve with rest and worsens with exertion. ME/CFS may involve inflammation in the brain and/or be associated with viral infections. Increased numb
Publikováno v:
Experimental Neurology. 164:362-370
Allogeneic or xenogenic tissues exhibit prolonged survival when grafted into the brain parenchyma in comparison to grafting into peripheral sites. The brain, therefore, has long been considered an immunologically privileged site. However, the immunol
Publikováno v:
Scopus-Elsevier
It is thought that protective immunity is mediated in part by Ag-experienced T cells that respond more quickly and vigorously than naive T cells. Using adoptive transfer of OVA-specific CD4 T cells from TCR transgenic mice as a model system, we show
Autor:
Randolph J. Noelle, Elizabeth Ingulli, Julia G. Johnson, Paul Garside, Rebecca Merica, Marc K. Jenkins
Publikováno v:
Science. 281:96-99
Early events in the humoral immune response were visualized in lymph nodes by simultaneous tracking of antigen-specific CD4 T and B cells after immunization. The T cells were initially activated in the T cell areas when the B cells were still randoml