Výsledky vyhledávání - "Rebecca M. Coleman"

A cluster of tetrodotoxin poisoning in Oman

Autor: Sultan Al Lawatia, Jerry D. Thomas, Vikas Kapil, Seif Al-Abri, Rebecca M. Coleman, Rudolph C. Johnson, Elizabeth I. Hamelin, Ziad Kazzi, Faryal Khamis, Badria Alhatali, Sandeep Kantur

Publikováno v: Clinical Toxicology. 60:262-266

Tetrodotoxin (TTX) is a potent sodium channel blocker, with significant neurotoxicity, found in marine animals like pufferfish and blue-ringed octopus. The severity of toxicity depends on the amount of toxin ingested and the outcome depends on the ti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25016ede667e36abdd8aac5584cb0b85
https://doi.org/10.1080/15563650.2021.1917595

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Detection of Brevetoxin in Human Plasma by ELISA

Autor: Elizabeth I. Hamelin, Rebecca M. Coleman, Rudolph C. Johnson, Adam M. Schaefer, Brady R. Cunningham

Publikováno v: Journal of analytical toxicology. 46(3)

Florida red tides have become more common and persistent in and around the Gulf of Mexico. When in bloom, red tides can produce brevetoxins in high concentrations, leading to human exposures primarily through contaminated food and ocean spray. The re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d71d274f04f02e3bac6b29f76f7177af
https://pubmed.ncbi.nlm.nih.gov/33515246

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Investigation of dried blood sampling with liquid chromatography tandem mass spectrometry to confirm human exposure to nerve agents

Autor: Jonas W. Perez, Ashli A. Brown, Rebecca M. Coleman, Nicholas D. Schulze, Rudolph C. Johnson, Craig Seymour, Rebecca L. Shaner, Elizabeth I. Hamelin, Kelsey Platanitis, Pearl Kaplan

Publikováno v: Analytica chimica acta. 1033

A method was developed to detect and quantify organophosphate nerve agent (OPNA) metabolites in dried blood samples. Dried blood spots (DBS) and microsampling devices are alternatives to traditional blood draws, allowing for safe handling, extended s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08583c69eb03c034d29e57ef885b98f4
https://pubmed.ncbi.nlm.nih.gov/30172315

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Quantitation of saxitoxin in human urine using immunocapture extraction and LC-MS

Autor: Christopher T. Elliott, Rudolph C. Johnson, Elizabeth I. Hamelin, Rebecca M. Coleman, William Bragg, Alaine Garrett, Katrina Campbell

Publikováno v: Bragg, W A, Garrett, A, Hamelin, E I, Coleman, R M, Campbell, K, Elliott, C T & Johnson, R C 2018, ' Quantitation of saxitoxin in human urine using immunocapture extraction and LC-MS ', Bioanalysis, vol. 10, no. 4, pp. 229-239 . https://doi.org/10.4155/bio-2017-0156

Aim: An immunomagnetic capture protocol for use with LC–MS was developed for the quantitation of saxitoxin (STX) in human urine. Materials & methods: This method uses monoclonal antibodies coupled to magnetic beads. STX was certified reference mate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f829419faef65d40991f6e4c3709fa6
https://pubmed.ncbi.nlm.nih.gov/29333869

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Detection of human exposure to saxitoxin and neosaxitoxin in urine by online-solid phase extraction-liquid chromatography–tandem mass spectrometry

Autor: Elizabeth I. Hamelin, Rudolph C. Johnson, Rebecca M. Coleman, Sharon W. Lemire, William Bragg

Publikováno v: Toxicon. 99:118-124

Saxitoxin (STX) and neosaxitoxin (NEO) are potent neurotoxins that cause paralytic shellfish poisoning (PSP). PSP typically occurs through the ingestion of bivalve shellfish that have consumed toxin producing dinoflagellates. Due to initial presentat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6615d7a2b2c4a00541ba4f1bf5ed845e
https://doi.org/10.1016/j.toxicon.2015.03.017

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Saxitoxin Exposure Confirmed by Human Urine and Food Analysis

Autor: Elizabeth I. Hamelin, M Cooper, Geovannie Ojeda-Torres, Donna A. Fearey, Rebecca M. Coleman, Jerry D. Thomas, Rudolph C. Johnson, William Bragg, P McKinney, Louisa Castrodale, D Verbrugge, K Stryker, E DeHart

Publikováno v: Journal of analytical toxicology. 42(7)

A case of an elderly female with suspected paralytic shellfish poisoning (PSP) is presented. The patient shared a meal of recreationally-harvested shellfish with her family and soon began to experience nausea and weakness. She was taken to the local

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d56641c6baeda1519e2ff14fdb7d1caf
https://pubmed.ncbi.nlm.nih.gov/29800291

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Quantitation of five organophosphorus nerve agent metabolites in serum using hydrophilic interaction liquid chromatography and tandem mass spectrometry

Autor: Edward M. Jakubowski, Nicholas D. Schulze, Brian S. Crow, Rebecca L. Shaner, Rebecca M. Coleman, Rudolph C. Johnson, Elizabeth I. Hamelin, Richard J. Lawrence

Publikováno v: Analytical and Bioanalytical Chemistry. 406:5195-5202

Although nerve agent use is prohibited, concerns remain for human exposure to nerve agents during decommissioning, research, and warfare. Exposure can be detected through the analysis of hydrolysis products in urine as well as blood. An analytical me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aac691a746da07ed1e60aa70e3418bb8
https://doi.org/10.1007/s00216-014-7702-2

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Development and validation of a high-throughput online solid-phase extraction-liquid chromatography-tandem mass spectrometry method for the detection of gonyautoxins 14 and gonyautoxins 23 in human urine

Autor: Geovannie Ojeda-Torres, Elizabeth I. Hamelin, Rebekah Wharton, Rebecca M. Coleman, Alaine Garrett, William Bragg, Rudolph C. Johnson, Jerry D. Thomas, Sharon W. Lemire

Publikováno v: Biomedical chromatography : BMC. 31(9)

Paralytic shellfish toxins (PSTs), including gonyautoxins and saxitoxins, are produced by multiple species of microalgae and dinoflagellates, and are bioaccumulated by shellfish and other animals. Human exposure to PSTs typically occurs through inges

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21685135c899c84a6b4025bd2b9db3a8
https://pubmed.ncbi.nlm.nih.gov/28186342

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Bridging the gap between sample collection and laboratory analysis: using dried blood spots to identify human exposure to chemical agents

Autor: Jonas W. Perez, Elizabeth I. Hamelin, Rebecca L. Shaner, Rudolph C. Johnson, Brian S. Crow, Thomas A. Blake, Rebecca M. Coleman

Publikováno v: SPIE Proceedings.

Public health response to large scale chemical emergencies presents logistical challenges for sample collection, transport, and analysis. Diagnostic methods used to identify and determine exposure to chemical warfare agents, toxins, and poisons tradi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65b60ff3b1f2879d2832cb3c409eed25
https://doi.org/10.1117/12.2223796

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Development and validation of a high-throughput online solid phase extraction - Liquid chromatography - Tandem mass spectrometry method for the detection of tetrodotoxin in human urine

Autor: Jerry D. Thomas, Sharon W. Lemire, Rebecca M. Coleman, Geovannie Ojeda-Torres, William Bragg, Rudolph C. Johnson, Alaine Garrett, Elizabeth I. Hamelin

Publikováno v: Toxicon : official journal of the International Society on Toxinology. 119

Tetrodotoxin (TTX) is an extremely potent paralytic toxin responsible for yearly illness and death around the world. A clinical measurement is necessary to confirm exposure because symptoms of TTX intoxication cannot be distinguished from other paral

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e79d02a2c7c9f5dc05131bbf496b2e8
https://pubmed.ncbi.nlm.nih.gov/27951505

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