Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Rebecca M DuBois"'
Autor:
Anisa Ghosh, Kevin Delgado-Cunningham, Tomás López, Kassidy Green, Carlos F Arias, Rebecca M DuBois
Publikováno v:
PLoS Pathogens, Vol 20, Iss 2, p e1012028 (2024)
Human astrovirus (HAstV) is a known cause of viral gastroenteritis in children worldwide, but HAstV can cause also severe and systemic infections in immunocompromised patients. There are three clades of HAstV: classical, MLB, and VA/HMO. While all th
Externí odkaz:
https://doaj.org/article/2a9fa5ec51c945f39836c21f7305fa5d
Autor:
Lena Meyer, Tomás López, Rafaela Espinosa, Carlos F Arias, Christopher Vollmers, Rebecca M DuBois
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0218717 (2019)
The diversity of antibody variable regions makes cDNA sequencing challenging, and conventional monoclonal antibody cDNA amplification requires the use of degenerate primers. Here, we describe a simplified workflow for amplification of IgG antibody va
Externí odkaz:
https://doaj.org/article/8cdc2efb582f495086d9231fb4962c99
Autor:
Rebecca M DuBois, P Jake Slavish, Brandi M Baughman, Mi-Kyung Yun, Ju Bao, Richard J Webby, Thomas R Webb, Stephen W White
Publikováno v:
PLoS Pathogens, Vol 8, Iss 8, p e1002830 (2012)
Emerging influenza viruses are a serious threat to human health because of their pandemic potential. A promising target for the development of novel anti-influenza therapeutics is the PA protein, whose endonuclease activity is essential for viral rep
Externí odkaz:
https://doaj.org/article/30fcbdf37e594ae99327103b81eb13cd
Autor:
Rebecca M DuBois, Hassan Zaraket, Muralidhar Reddivari, Richard J Heath, Stephen W White, Charles J Russell
Publikováno v:
PLoS Pathogens, Vol 7, Iss 12, p e1002398 (2011)
Highly pathogenic avian influenza viruses of the H5N1 subtype continue to threaten agriculture and human health. Here, we use biochemistry and x-ray crystallography to reveal how amino-acid variations in the hemagglutinin (HA) protein contribute to t
Externí odkaz:
https://doaj.org/article/e09d4bebb97d49c48a30c6137ade9502
Autor:
José M Aguilar-Yáñez, Roberto Portillo-Lara, Gonzalo I Mendoza-Ochoa, Sergio A García-Echauri, Felipe López-Pacheco, David Bulnes-Abundis, Johari Salgado-Gallegos, Itzel M Lara-Mayorga, Yenny Webb-Vargas, Felipe O León-Angel, Ramón E Rivero-Aranda, Yuriana Oropeza-Almazán, Guillermo M Ruiz-Palacios, Manuel I Zertuche-Guerra, Rebecca M DuBois, Stephen W White, Stacey Schultz-Cherry, Charles J Russell, Mario M Alvarez
Publikováno v:
PLoS ONE, Vol 5, Iss 7, p e11694 (2010)
The A/H1N1/2009 influenza pandemic made evident the need for faster and higher-yield methods for the production of influenza vaccines. Platforms based on virus culture in mammalian or insect cells are currently under investigation. Alternatively, exp
Externí odkaz:
https://doaj.org/article/92879a1591914b66b9e8aa1c5572aabf
Autor:
Harrison C. Bergeron, Jackelyn Murray, Aakash Arora, Ana M. Nuñez Castrejon, Rebecca M. DuBois, Larry J. Anderson, Lawrence M. Kauvar, Ralph A. Tripp
Publikováno v:
Viruses; Volume 15; Issue 5; Pages: 1067
The respiratory syncytial virus (RSV) causes significant respiratory disease in young infants and the elderly. Immune prophylaxis in infants is currently limited to palivizumab, an anti-RSV fusion (F) protein monoclonal antibody (mAb). While anti-F p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70f4db9bffacd021e07434a137400f63
Autor:
John V. Dzimianski, Julianna Han, Giuseppe A. Sautto, Sara M. O’Rourke, Joseph M. Cruz, Spencer R. Pierce, Jeffrey W. Ecker, Michael A. Carlock, Kaito A. Nagashima, Jarrod J. Mousa, Ted M. Ross, Andrew B. Ward, Rebecca M. DuBois
Publikováno v:
Communications biology, vol 6, iss 1
Influenza virus poses an ongoing human health threat with pandemic potential. Due to mutations in circulating strains, formulating effective vaccines remains a challenge. The use of computationally optimized broadly reactive antigen (COBRA) hemagglut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a544b30147b4a53ae49440d6eecf4c42
https://escholarship.org/uc/item/8bk4r8vf
https://escholarship.org/uc/item/8bk4r8vf
Autor:
Peter J. Slavish, Maxime G. Cuypers, Mary Ashley Rimmer, Alireza Abdolvahabi, Trushar Jeevan, Gyanendra Kumar, Jamie A. Jarusiewicz, Sivaraja Vaithiyalingam, Jeremy C. Jones, John J. Bowling, Jeanine E. Price, Rebecca M. DuBois, Jaeki Min, Richard J. Webby, Zoran Rankovic, Stephen W. White
Publikováno v:
European journal of medicinal chemistry. 247
Influenza is one of the leading causes of disease-related mortalities worldwide. Several strategies have been implemented during the past decades to hinder the replication cycle of influenza viruses, all of which have resulted in the emergence of res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::315458fce671f85ad413483c62860fde
https://pubmed.ncbi.nlm.nih.gov/36603507
https://pubmed.ncbi.nlm.nih.gov/36603507
Autor:
Kaito Nagashima, John V. Dzimianski, Julianna Han, Nada Abbadi, Aaron D. Gingerich, Fredejah Royer, Sara O’Rourke, Giuseppe A. Sautto, Ted M. Ross, Andrew B. Ward, Rebecca M. DuBois, Jarrod J. Mousa
Publikováno v:
J Immunol
Journal of immunology (Baltimore, Md. : 1950), vol 209, iss 1
Journal of immunology (Baltimore, Md. : 1950), vol 209, iss 1
Computationally optimized broadly reactive Ag (COBRA) hemagglutinin (HA) immunogens have previously been generated for several influenza subtypes to improve vaccine-elicited Ab breadth. As nearly all individuals have pre-existing immunity to influenz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2e5a3fe153aabe76bc322650a3b1303
https://europepmc.org/articles/PMC9246865/
https://europepmc.org/articles/PMC9246865/
Publikováno v:
Structure (London, England : 1993). 30(12)
Despite their worldwide prevalence and association with human disease, the molecular bases of human astrovirus (HAstV) infection and evolution remain poorly characterized. Here, we report the structure of the capsid protein spike of the divergent HAs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b86d1dfa21e24f160bd86d91466317d
https://pubmed.ncbi.nlm.nih.gov/36417907
https://pubmed.ncbi.nlm.nih.gov/36417907